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anti-Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) Antibodies

CYP24A1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP24A1 Kits (12) and CYP24A1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP24A1 1591 Q07973
CYP24A1 13081 Q64441
CYP24A1 25279 Q09128
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Top anti-CYP24A1 Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated EIA, WB AP22432PU-N CYP24A1 antibody staining of Human Liver lysate at 0.1 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Western blot analysis of CYP24A1 Antibody (C-term) in mouse spleen tissue lysates (35ug/lane). CYP24A1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from JurKat cells, using Cytochrome P450 24A1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-CYP24A1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: MCF7 cell lysate WB Suggested Anti-CYP24A1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged CYP24A1 is approximately 1ng/ml as a capture antibody. Western Blot analysis of CYP24A1 expression in transfected 293T cell line by CYP24A1 monoclonal antibody (M02), clone 1E1.Lane 1: CYP24A1 transfected lysate (Predicted MW: 11.11 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- CYP24A1 Picoband antibody, IHC(P) IHC(P): Human Pancreatic Cancer Tissue Anti- CYP24A1 Picoband antibody, IHC(P) IHC(P): Mouse Kidney Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image CYP24A1 antibody detects CYP24A1 protein at cytosol on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. CYP24A1 antibody , dilution: 1:500. WB Image Sample(30μg whole cell lysate) A: 293T B: A431 , C: H1299 D: HeLa S3 , E: Hep G2 , F: MOLT4 , G: Raji , 7.5% SDS PAGE antibody diluted at 1:3000 100 μL Log in to see 2 to 3 Days
$358.60
Details

CYP24A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CYP24A1 Antibodies

  1. Human Polyclonal CYP24A1 Primary Antibody for ELISA, WB - ABIN560551 : Peng, Jhaveri, Hussain-Hakimjee, Mehta: Overexpression of ER and VDR is not sufficient to make ER-negative MDA-MB231 breast cancer cells responsive to 1alpha-hydroxyvitamin D5. in Carcinogenesis 2007 (PubMed)
    Show all 2 references for ABIN560551

  2. Human Polyclonal CYP24A1 Primary Antibody for EIA, WB - ABIN569640 : Shen, Bielak, Ferguson, Streeten, Yerges-Armstrong, Liu, Post, OConnell, Hixson, Kardia, Sun, Jhun, Wang, Mehta, Li, Koller, Hakonarson, Keating, Rader, Shuldiner, Peyser, Reilly, Mitchell: Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification. in Arteriosclerosis, thrombosis, and vascular biology 2010 (PubMed)

  3. Human Polyclonal CYP24A1 Primary Antibody for ELISA, WB - ABIN1534377 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)

  4. Human Polyclonal CYP24A1 Primary Antibody for EIA, IHC (p) - ABIN453594 : Okuda, Usui, Ohyama: Recent progress in enzymology and molecular biology of enzymes involved in vitamin D metabolism. in Journal of lipid research 1995 (PubMed)

  5. Human Monoclonal CYP24A1 Primary Antibody for ELISA, WB - ABIN514852 : Helvig, Cuerrier, Hosfield, Ireland, Kharebov, Kim, Ramjit, Ryder, Tabash, Herzenberg, Epps, Petkovich: Dysregulation of renal vitamin D metabolism in the uremic rat. in Kidney international 2010 (PubMed)

More Antibodies against CYP24A1 Interaction Partners

Human Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) interaction partners

  1. most heterozygous CYP24A1 mutation carriers have a normal 25OHD/24,25(OH)2D ratio, are usually asymptomatic and have a normal skeletal status but may possibly be at increased risk of nephrocalcinosis

  2. CYP24A1 expression is closely associated with colorectal cancer progression, and it might be a novel prognostic biomarker for CRC (show CALR Antibodies).

  3. The CYP24A1 SNP rs927650 may be related to both circulating blood concentrations of 25-hydroxyvitamin D as well as to odds of recurrent colorectal neoplasia.

  4. A definite alteration was seen in vitamin D3-inactivating CYP24A1 gene activity in papillary thyroid carcinoma compared to their normal tissues on a relatively large patient population.

  5. Vitamin D-binding protein (show GC Antibodies) SNPs are associated with prostate cancer; low 25(OH)D metabolism score and CYP24A1 and CYP27B1 (show CYP27B1 Antibodies) variants are associated with grade

  6. Breast cancer risk may be associated with specific vitamin D-related polymorphisms, particularly CYP24A1 and VDR (show CYP27B1 Antibodies).

  7. CYP24A1 biallelic mutations are frequently found in patients presenting with hypercalcemia, low PTH (show PTH Antibodies), and renal disease. Haploinsufficiency is not associated with CYP24A1 deficiency.

  8. Data show that cytochrome P450 (show CYP Antibodies) CYP27B1 (show CYP27B1 Antibodies) and CYP24A1 expression were significantly different between tumor and normal tissues in non-small cell lung cancer (NSCLC).

  9. Data suggest that expression of CYP24A1 and cathelicidin is up-regulated in placental extravillous trophoblasts by vitamin D metabolites 1,23-dihydroxyvitamin D3 and 25-hydroxyvitamin D3.

  10. propose three potential human candidate genes for voluntary physical exercise levels (MC3R (show MC3R Antibodies), CYP24A1, and GRM8 (show GRM8 Antibodies)).

Mouse (Murine) Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) interaction partners

  1. results link CYP24 activity to the pathophysiology of FGF23 (show FGF23 Antibodies)-dependent renal phosphate wasting states and implicate pharmacologic CYP24 inhibition as a therapeutic adjunct for their treatment.

  2. Gsalpha is required in proximal tubules for suppressing renal vitamin D 24-hydroxylase mRNA levels and for maintaining normal serum 1,25(OH)2D.

  3. Data suggest that control of CYP24A1 increase during diabetes has a beneficial effect on senescence induction and caspase-3 (show CASP3 Antibodies) increased expression.

  4. the mechanism through which 1,25(OH)(2)D(3) induces the CYP24A1 enzyme

  5. The expression of vitamin D 24-hydroxylase gene was directly regulated by serum calcium rather than 25-hydroxyvitamin D 1 alpha-hydroxylase.

  6. Results show that Inhibition of 24-OHase activity modulates serum calcitriol PK in normal C3H/HeJ mice.

  7. Cyp24a1 deficiency delays fracture repair and strongly suggest that vitamin D metabolites hydroxylated at position 24, such as 24,25(OH)2D3, play an important role in the mechanisms leading to normal fracture hea (show TTC7A Antibodies)

  8. 1,25(OH)2D is the preferred substrate for CYP24 in murine kidney mitochondria.

  9. findings demonstrate that regulation of both the 25-hydroxyvitamin D-1 alpha-hydroxylase and 25-hydroxyvitamin D-24-hydroxylase genes by phosphorus is disordered in hypophosphatemic mice at the level of renal mRNA expression

  10. the absence of CYP24A1 or vitamin D receptor (show VDR Antibodies) retards catabolism of 1alpha,25(OH)2D3 and 25(OH)D3

CYP24A1 Antigen Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CYP24A1

  • cytochrome P450, family 24, subfamily A, polypeptide 1 (CYP24A1) antibody
  • cytochrome P450, family 24, subfamily a, polypeptide 1 (Cyp24a1) antibody
  • 24-OHase antibody
  • 25-hydroxyvitaminD324-hydroxylase antibody
  • CP24 antibody
  • CP450CC24 antibody
  • Cyp24 antibody
  • HCAI antibody
  • P450-CC24 antibody
  • VITD12 antibody

Protein level used designations for CYP24A1

1,25-@dihydroxyvitamin D3 24-hydroxylase , 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial , 24-OHase , cytochrome P450 24A1 , cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase) , cytochrome P450-CC24 , exo-mitochondrial protein , vitamin D 24-hydroxylase , vitamin D(3) 24-hydroxylase , 25-hydroxyvitamin D-24-hydroxylase , cytochrome P450, 24 , cytochrome P450, 24a1 , 24R-Ohase , 25-hydroxyvitamin D3 24-hydroxylase , Cytochrom P450 (25-hydroxyvitamin D24-hydroxylase) , P450-CC24 , cytochrome P450, subfamily 24 , 25-hydroxyvitamin D3-24-hydroxylase

GENE ID SPECIES
1591 Homo sapiens
13081 Mus musculus
25279 Rattus norvegicus
395827 Gallus gallus
485935 Canis lupus familiaris
397145 Sus scrofa
540080 Bos taurus
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