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anti-Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1) Antibodies

CYP46A1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 Kits (8) and Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP46A1 10858 Q9Y6A2
CYP46A1 13116 Q9WVK8
CYP46A1 362782  
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Top anti-Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CYP46A1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated EIA, WB   0.1 mL Log in to see 6 to 8 Days
$467.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged CYP46A1 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB CYP46A1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated IP, ELISA, WB Detection limit for recombinant GST tagged CYP46A1 is 0.03 ng/ml as a capture antibody. Immunoprecipitation of CYP46A1 transfected lysate using anti-CYP46A1 monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with CYP46A1 MaxPab rabbit polyclonal antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged CYP46A1 is approximately 0.03ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 9 Days
$430.00
Details

CYP46A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 Antibodies

  1. Human Polyclonal CYP46A1 Primary Antibody for EIA, WB - ABIN318821 : Pikuleva: Cytochrome P450s and cholesterol homeostasis. in Pharmacology & therapeutics 2006 (PubMed)
    Show all 3 references for ABIN318821

  2. Cow (Bovine) Polyclonal CYP46A1 Primary Antibody for WB - ABIN2773829 : Galluzzi, Geroldi, Benussi, Ghidoni, Testa, Borsci, Bonetti, Manfellotto, Romanelli, Zulli, Binetti, Frisoni: Association of blood pressure and genetic background with white matter lesions in patients with mild cognitive impairment. in The journals of gerontology. Series A, Biological sciences and medical sciences 2008 (PubMed)

More Antibodies against Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 Interaction Partners

Human Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1) interaction partners

  1. hippocampal CYP46A1 protein and 24S-hydroxycholesterol levels were reduced in a mouse model of Alzheimer's Disease-like Tau neuropathology

  2. under conditions of membrane cholesterol reduction by increased CYP46A1 expression, neurons increase isoprenoid synthesis and sGTPase prenylation. This leads to a reduction in liver X receptor activity

  3. Human CYP46A1 oxidizes 7-dehydrocholesterol to 24-hydroxy-7-dehydrocholesterol and 25-hydroxy-7-dehydrocholesterol.

  4. While there were no differences in cognitive performance between participants with and those without metabolic syndrome, ApoE (show APOE Antibodies) and CYP46 genotypes did correlate with mental manipulation scores.

  5. results of meta-analysis suggested that CYP46A1 rs754203 is a minor risk factor for Alzheimer's disease

  6. An meta-analysis has successfully proved that CC genotype of the CYP46A1 T/C polymorphism could increase the risk of Alzheimer's disease.

  7. A meta-analysis indicates that the CYP46 gene SNP rs754203 is not significantly associated with sporadic Alzheimer's disease susceptibility in Chinese Han populations.

  8. To identify the determinants of tight azole binding to CYP46A1.

  9. analysis of binding of the cyano- and fluoro-containing drug bicalutamide to cytochrome P450 46A1

  10. The intronic polymorphism in CYP46A1 is associated with Alzheimer disease in a Chinese Han population, and the CYP46A1 T allele might be a risk factor.

Cow (Bovine) Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1) interaction partners

  1. EFV enhanced CYP46A1 activity and cerebral cholesterol turnover in animals with no effect on the levels of brain cholesterol.

  2. analysis of binding of the cyano- and fluoro-containing drug bicalutamide to cytochrome P450 46A1

Mouse (Murine) Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1) interaction partners

  1. Increased expression of CYP46A1 in the striatum decreased neuronal atrophy in a Huntington's disease model.

  2. under conditions of membrane cholesterol reduction by increased CYP46A1 expression, neurons increase isoprenoid synthesis and sGTPase prenylation. This leads to a reduction in liver X receptor activity

  3. EFV enhanced CYP46A1 activity and cerebral cholesterol turnover in animals with no effect on the levels of brain cholesterol.

  4. the CYP46 gene locus may predispose to Alzheimer's disease by increasing the 24S-hydroxycholesterol/cholesterol ratio in the brain.

  5. The expression of CYP46A1, as well as other cytochrome P450s involved in cholesterol homeostasis, are potently regulated by histone acetylation status.

Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1) Antigen Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

Gene names and symbols associated with CYP46A1

  • cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1) antibody
  • cytochrome P450, family 46, subfamily A, polypeptide 1 (cyp46a1) antibody
  • cytochrome P450, family 46 (cyp46a1) antibody
  • cytochrome P450 46A1 (PTRG_08343) antibody
  • cytochrome P450 46A1 (PTRG_09667) antibody
  • cholesterol 24-hydroxylase (Sgly_1093) antibody
  • cytochrome P450, family 46, subfamily a, polypeptide 1 (Cyp46a1) antibody
  • CP46 antibody
  • Cyp46 antibody
  • CYP46A1 antibody
  • MGC147389 antibody
  • zgc:109896 antibody

Protein level used designations for CYP46A1

cholesterol 24-hydroxylase , cytochrome P450, family 46, subfamily A, polypeptide 1 , cytochrome P450, family 46 , cytochrome P450 46A1 , CH24H , cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase) , cholesterol-24S-hydroxylase , cholestrol 24-hydroxylase , cytochrome P450, 46 (cholesterol 24-hydroxylase) , cytochrome P450, 46a1 (cholesterol 24-hydroxylase)

GENE ID SPECIES
423450 Gallus gallus
453154 Pan troglodytes
553543 Danio rerio
780005 Xenopus (Silurana) tropicalis
100145328 Xenopus (Silurana) tropicalis
6346625 Pyrenophora tritici-repentis Pt-1C-BFP
6347960 Pyrenophora tritici-repentis Pt-1C-BFP
10248273 Syntrophobotulus glycolicus DSM 8271
10858 Homo sapiens
379470 Xenopus laevis
506438 Bos taurus
13116 Mus musculus
362782 Rattus norvegicus
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