Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) ELISA Kits

CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. Additionally we are shipping CTLA4 Antibodies (452) and CTLA4 Proteins (85) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CTLA4 12477 P09793
CTLA4 1493 P16410
CTLA4 63835  
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Top CTLA4 ELISA Kits at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.055 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 15 to 17 Days
$762.82
Details
Mouse 10pg/mL 156-10000 pg/mL Mouse CTLA4 PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
$369.00
Details
Rat 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$638.00
Details
Human 0.33 ng/mL 0.78-50 ng/mL   96 Tests Log in to see 2 to 3 Days
$691.90
Details
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Rabbit 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Chicken 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Guinea Pig 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Cow
  96 Tests Log in to see 15 to 18 Days
$707.14
Details
Monkey
  96 Tests Log in to see 15 to 18 Days
$707.14
Details

More ELISA Kits for CTLA4 Interaction Partners

Rhesus Monkey Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. Data show that CTLA-4(+)PD-1 (show PDCD1 ELISA Kits)(-) memory CD4 (show CD4 ELISA Kits)(+) T cells, which share phenotypic markers with regulatory T cells, were enriched in SIV DNA in blood, lymph nodes (LN), spleen, and gut (show GUSB ELISA Kits), and contained replication-competent and infectious virus.

Mouse (Murine) Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. data suggest that increased expression of checkpoint blockade molecules PD-1 (show PDCD1 ELISA Kits) and CTLA-4 on donor T cells is not sufficient to prevent GvHD, and that cooperation between checkpoint blockade signaling by host cells and donor Tregs is necessary to limit GvHD in allo-HSCT recipients

  2. Treg cells expand in both humans and mice in blood-stage malaria and interfere with conventional T helper cell responses and follicular T helper (TFH)-B cell interactions in germinal centers. Mechanistically, Treg cells function in a critical temporal window to impede protective immunity through cytotoxic-T-lymphocyte-associated protein-4 (CTLA-4).

  3. CTLA-4 expressed by FOXP3 (show FOXP3 ELISA Kits)(+) regulatory T cells prevents inflammatory tissue attack and not T-cell priming in arthritis.

  4. results are consistent with a complex pathway in which CD28 (show CD28 ELISA Kits) is the primary driver of Treg proliferation and CTLA-4 functions as the main brake but is also dependent on TCR signals and interactions with CD80 (show CD80 ELISA Kits)/CD86 (show CD86 ELISA Kits)

  5. CTLA-4(+) microvesicles can competitively bind B7 costimulatory molecules on bystander dendritic cells, resulting in downregulation of B7 surface expression.

  6. this study shows that miR (show MLXIP ELISA Kits)-155 is modulated by a major dust mite allergen, Dermatophagoides farinae (Df1), and increases CD4 (show CD4 ELISA Kits)+ T cell proliferation through the downregulation of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expression

  7. CTLA-4 regulates atherosclerosis by suppressing proatherogenic immune responses.

  8. Data suggest enhanced clinical benefit from combining CTLA-4 antigen blockade with poxvirus-based active immunotherapy.

  9. up-regulated expression correlates with the tolerogenic effect of syngeneic hematopoietic stem cell transplantation

  10. Induced Treg Cells Augment the Th17-Mediated Intestinal Inflammatory Response in a CTLA4-Dependent Manner

Human Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. CTLA-4 expressing Th17 cells may present regulatory activities in pancreatic cancer patients.

  2. Data show there was an independent negative prognostic impact of cytotoxic T lymphocyte associated antigen 4 (T-CTLA-4) expression in metastatic lymph nodes.

  3. High CTLA4 expression is associated with B-cell lymphoma.

  4. In this discovery cohort, the combination of PD-1 (show PDCD1 ELISA Kits) and CTLA-4 emerged as the best predictor of response. Patients whose tumors had at least 20% of CD8 (show CD8A ELISA Kits)+ T cells expressing these two markers had a median progression-free survival of 31.6 months, versus 9.6 months for patients with less than 20% of this subtype among their tumor CD8 (show CD8A ELISA Kits)+ cells

  5. Review/Meta-analysis: CTLA-4 may not be a major susceptibility locus in humans with ankylosing spondylitis.

  6. Treg cells expand in both humans and mice in blood-stage malaria and interfere with conventional T helper cell responses and follicular T helper (TFH)-B cell interactions in germinal centers. Mechanistically, Treg cells function in a critical temporal window to impede protective immunity through cytotoxic-T-lymphocyte-associated protein-4 (CTLA-4).

  7. This review focuses on the pathogenesis, clinical manifestations and management of immune-related toxicity of anti-CTLA-4 and anti-PD-1 (show PDCD1 ELISA Kits) antibodies

  8. The CTLA-4 blockade may restore Th1 (show TH1L ELISA Kits) function in patients with COPD (show ARCN1 ELISA Kits) and so aid the clearance of bacterial pathogens responsible for acute exacerbations of chronic obstructive pulmonary disease.

  9. High CTLA4 expression is associated with head-and-neck squamous cell carcinoma.

  10. AUthors observed a significant correlation between the proportion of Tregs and (in)CTLA-4+ Tregs with IL-17A (show IL17A ELISA Kits) concentration in clBALF. Data confirmed significant differences in the proportion of regulatory elements between cancerous lung and healthy lung and PB and the usefulness of BALF analysis in evaluation of immune response regulation in local lung cancer environment.

Pig (Porcine) Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. Suggest a truncated diphtheria toxin based recombinant porcine CTLA-4 fusion toxin as a novel approach for in vivo depletion of CD80 (show CD80 ELISA Kits)-positive cells.

Cow (Bovine) Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. The surface expression of CTLA-4 was increased in subclinical stages of paratuberculosis infection while levels of ZAP-70 (show ZAP70 ELISA Kits) were decreased in CD4 (show CD4 ELISA Kits)+ T cells of both subclinical and clinical animals, indicating a change in T cell phenotype with disease state.

  2. These results suggested that the expression level of CTLA-4 in CD4 (show CD4 ELISA Kits)-positive T cells has a potentially immunosuppressive function in bovine leukemia infection.

  3. Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 (show FOXP3 ELISA Kits) and CTLA4.

CTLA4 Antigen Profile

Antigen Summary

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

Gene names and symbols associated with CTLA4

  • cytotoxic T-lymphocyte-associated protein 4 precursor (CTLA-4) antibody
  • cytotoxic T-lymphocyte-associated protein 4 (CTLA4) antibody
  • cytotoxic T-lymphocyte-associated protein 4 (LOC100222727) antibody
  • cytotoxic T-lymphocyte-associated protein 4 (Ctla4) antibody
  • CD antibody
  • Cd152 antibody
  • CELIAC3 antibody
  • Ctla-4 antibody
  • CTLA4 antibody
  • GRD4 antibody
  • GSE antibody
  • IDDM12 antibody
  • Ly-56 antibody
  • sCTLA4 antibody

Protein level used designations for CTLA4

cytotoxic T-lymphocyte-associated protein 4 precursor , CD152 protein , cytotoxic T-lymphocyte protein 4 , cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM , cytotoxic T-lymphocyte-associated protein 4 , costimulatory molecule B7 receptor , cytotoxic T lymphocyte-associated antigen 4 , CD152 antigen , cytotoxic T-lymphocyte-associated antigen 4 , CD152 isoform , celiac disease 3 , cytotoxic T lymphocyte associated antigen 4 short spliced form , cytotoxic T-lymphocyte antigen 4 , cytotoxic T-lymphocyte-associated serine esterase-4 , ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 , soluble form , transmembrane form , CTLA-4 , cytotoxic T lymphocyte-associated protein 4 , costimulatory molecule B7 receptor CD152

GENE ID SPECIES
443040 Ovis aries
705673 Macaca mulatta
100222727 Taeniopygia guttata
424106 Gallus gallus
470619 Pan troglodytes
493743 Felis catus
100126716 Papio anubis
12477 Mus musculus
1493 Homo sapiens
63835 Rattus norvegicus
100009412 Oryctolagus cuniculus
397286 Sus scrofa
403696 Canis lupus familiaris
281732 Bos taurus
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