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anti-DBF4 Homolog (S. Cerevisiae) (DBF4) Antibodies

Regulatory subunit for cdc7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Additionally we are shipping DBF4 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DBF4 10926 Q9UBU7
DBF4 27214 Q9QZ41
DBF4 312046  
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Top anti-DBF4 Antibodies at antibodies-online.com

Showing 10 out of 61 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IF, ELISA, WB Detection limit for recombinant GST tagged DBF4 is approximately 0.1ng... Immunofluorescence of monoclonal antibody to DBF4 on HeLa cell. [antib... 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, treated with H2O... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Mouse Goat Un-conjugated EIA, WB AP31104PU-N DBF4 antibody staining of Mouse Testis lysate at 1 µg/ml (... 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Cow Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of DBF4 staining in HepG2 cells. Formalin-f... Immunohistochemical analysis of DBF4 staining in human brain formalin ... 200 μL Log in to see 9 Days
$487.50
Details
Mouse Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot (WB) analysis of Dbf4 antibody in extracts from NIH-3T3 t... 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated DB 50 μg Log in to see 7 to 9 Days
$285.71
Details

DBF4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,
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Top referenced anti-DBF4 Antibodies

  1. Human Monoclonal DBF4 Primary Antibody for IF, ELISA - ABIN564742 : Hughes, Jenkins, Dar, Engelman, Cherepanov: Transcriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activity. in The Journal of biological chemistry 2009 (PubMed)

More Antibodies against DBF4 Interaction Partners

Human DBF4 Homolog (S. Cerevisiae) (DBF4) interaction partners

  1. The anti-invasive and cell cycle arrest-inducing effects of nitrogen-containing bisphosphonates are not DBF4 mediated in human breast cancer cells.

  2. Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.

  3. bipartite interaction between Cdc7 (show CDC7 Antibodies) and Dbf4/ASK subunits facilitates ATP binding and substrate recognition by the Cdc7 (show CDC7 Antibodies) kinase.

  4. Dbf4 regulates the Cdc5 (show CDC5L Antibodies) Polo-like kinase (show PLK1 Antibodies) through a distinct non-canonical binding interaction

  5. Data document the role of DBF4 as a key player in nitrogen-containing bisphosphonate-induced cytotoxicity, thus explaining the effects on the cell-cycle.

  6. The interaction with LEDGF (show PSIP1 Antibodies) relieves autoinhibition of Cdc7 (show CDC7 Antibodies)-ASK kinase, imposed by the C terminus of ASK.

  7. results suggest that E2F (show E2F1 Antibodies) regulates the ASK promoter through an atypical mode of recognition of the target site

  8. The HuDbf4 gene has of 12 exons over a 33-kb region. The MluI cell-cycle box is needed for core promoter activation. The Sp1 upregulator & HES-1 repressor coordinately determine promoter efficiency. Transcription initiations occur at -220, -235 and -245.

  9. Results demonstrate a DNA damage checkpoint that targets Cdc7/Dbf4 protein kinase.

  10. Cdc7 (show CDC7 Antibodies)-Dbf4 kinase efficiently phosphorylates p150 (show ABL1 Antibodies).

DBF4 Antigen Profile

Protein Summary

Regulatory subunit for cdc7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Not required during the initiation of DNA replication in egg and during early embryonic development but is required later and throughout development. The complex cdc7-dbf4a phosphorylates mcm2 subunit.

Gene names and symbols associated with DBF4

  • DBF4 homolog (S. cerevisiae) (DBF4) antibody
  • DBF4 homolog B (S. cerevisiae) (DBF4B) antibody
  • DBF4 homolog (S. cerevisiae) (dbf4) antibody
  • DBF4 homolog (S. cerevisiae) (LOC100229596) antibody
  • DBF4 homolog (dbf4) antibody
  • DBF4 homolog (S. cerevisiae) (Dbf4) antibody
  • AA545217 antibody
  • Ask antibody
  • ChDBF4 antibody
  • CHIF antibody
  • DBF4 antibody
  • DBF4A antibody
  • DBF4B antibody
  • LOC100229596 antibody
  • RGD1305854 antibody
  • xdbf4 antibody
  • ZDBF1 antibody

Protein level used designations for DBF4

DBF4 homolog (S. cerevisiae) , DBF4 homolog B (S. cerevisiae) , activator of S phase kinase , protein DBF4 homolog A , protein DBF4 homolog A-like , DBF4-type zinc finger-containing protein 1 , chiffon homolog A , zinc finger, DBF-type containing 1

GENE ID SPECIES
420536 Gallus gallus
454734 Pan troglodytes
472668 Pan troglodytes
475219 Canis lupus familiaris
480497 Canis lupus familiaris
510916 Bos taurus
705468 Macaca mulatta
771128 Gallus gallus
790361 Bos taurus
799015 Danio rerio
100050313 Equus caballus
100192446 Sus scrofa
100229596 Taeniopygia guttata
100027385 Monodelphis domestica
100339152 Oryctolagus cuniculus
100396428 Callithrix jacchus
100451466 Pongo abelii
100476446 Ailuropoda melanoleuca
100579391 Nomascus leucogenys
398599 Xenopus laevis
10926 Homo sapiens
27214 Mus musculus
312046 Rattus norvegicus
100689339 Cricetulus griseus
Selected quality suppliers for anti-DBF4 (DBF4) Antibodies
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