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DBF4 Products

(DBF4 Homolog (DBF4))

Categories

Regulatory subunit for cdc7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Not required during the initiation of DNA replication in egg and during early embryonic development but is required later and throughout development. The complex cdc7-dbf4a phosphorylates mcm2 subunit.

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Featured DBF4 Categories

DBF4 Antibodies

High quality antibodies with extensive validation data.

DBF4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DBF4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (4)
Cat. No. ABIN564742
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7165242
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6257125
Quantity 100 μL
Datasheet Datasheet

Recommended DBF4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6203693
Quantity 96 tests
Datasheet Datasheet

Recommended DBF4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351145
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351144
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3092050
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DBF4 products

Hughes, Jenkins, Dar, Engelman, Cherepanov: "Transcriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activity." in: The Journal of biological chemistry, Vol. 285, Issue 1, pp. 541-54, (2009) (PubMed).

Tsuji, Lau, Chiang, Jiang: "The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control." in: Molecular cell, Vol. 32, Issue 6, pp. 862-9, (2008) (PubMed).

Nambiar, Mirmohammadsadegh, Hassan, Mota, Marini, Alaoui, Tannapfel, Hegemann, Hengge: "Identification and functional characterization of ASK/Dbf4, a novel cell survival gene in cutaneous melanoma with prognostic relevance." in: Carcinogenesis, Vol. 28, Issue 12, pp. 2501-10, (2007) (PubMed).

Tsuji, Ficarro, Jiang: "Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells." in: Molecular biology of the cell, Vol. 17, Issue 10, pp. 4459-72, (2006) (PubMed).

Synonyms and alternative names related to DBF4

DBF4 zinc finger (DBF4), DBF4 zinc finger (dbf4), DBF4 zinc finger (Dbf4), DBF4 zinc finger L homeolog (dbf4.L), AA545217, ASK, Ask, ChDBF4, CHIF, DBF4, DBF4A, dbf4a, LOC100229596, RGD1305854, xdbf4, ZDBF1

Protein level used designations for DBF4

  • DBF4-type zinc finger-containing protein 1
  • activator of S phase kinase
  • chiffon homolog A
  • protein DBF4 homolog A
  • zinc finger, DBF-type containing 1
  • DBF4 homolog (S. cerevisiae)
  • protein DBF4 homolog A-like
  • DBF4 homolog
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