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anti-Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) (DACT2) Antibodies

Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors (By similarity).. Additionally we are shipping Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DACT2 240025 Q7TN08
DACT2 168002 Q5SW24
DACT2 308212  
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Top anti-Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) Antibodies at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of Dact2 in human brain tissue with Dact2 antibody at 2.5 μg/ml. Western blot analysis of Dact2 in SK-N-SH cell lysate with AP30269PU-N Dact2 antibody at 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 6 to 11 Days
$535.71
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   0.1 mg Log in to see 2 to 6 Days
$416.90
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μL Log in to see 2 to 3 Days
$429.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   100 μg Log in to see 11 to 16 Days
$499.71
Details

DACT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human


Rat (Rattus)


Top referenced anti-Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) Antibodies

  1. Human Polyclonal DACT2 Primary Antibody for EIA, IHC (p) - ABIN499702 : Shimogori, VanSant, Paik, Grove: Members of the Wnt, Fz, and Frp gene families expressed in postnatal mouse cerebral cortex. in The Journal of comparative neurology 2004 (PubMed)
    Show all 4 references for ABIN499702

  2. Human Polyclonal DACT2 Primary Antibody for IHC, ELISA - ABIN1031341 : Zhang, Yang, Liu, Herman, Brock, Licchesi, Yue, Pei, Guo: Epigenetic regulation of the Wnt signaling inhibitor DACT2 in human hepatocellular carcinoma. in Epigenetics : official journal of the DNA Methylation Society 2013 (PubMed)

More Antibodies against Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) Interaction Partners

Mouse (Murine) Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) (DACT2) interaction partners

  1. we have identified a novel role for Dact2 as an inhibitor of the canonical Wnt (show WNT2 Antibodies) pathway in embryonic tooth development through its regulation of cell proliferation and differentiation.

  2. conserved role for Dact2 protein in kinase-regulated biochemistry involving Vangl and Dvl (show DVL1 Antibodies).

  3. Dact2 plays a role in regulating morphogenesis by renal collecting duct cells, probably by protecting cells from overly strong TGF-beta (show TGFB1 Antibodies) pathway activation.

  4. Dact2 may play important signal-modulating roles in the adjacent epithelial cells including the enamel knot (show KCNK7 Antibodies) signaling centers and pre-ameloblasts.

  5. Dact2 expression is most prominent during organogenesis of the thymus, kidneys, and salivary glands, with much lower levels in the somites and in the developing CNS.

  6. Dpr2 plays an inhibitory role in the re-epithelialization of adult skin wounds by attenuating TGFbeta (show TGFB1 Antibodies) signaling.

Human Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) (DACT2) interaction partners

  1. This study demonstrated that Genes overexpressed in Pilomyxoid Astrocytoma vs. Pilocytic Astrocytoma, ranked according to fold-change, included developmental genes H19 (show NCKAP1 Antibodies), DACT2,COL2A1 (show COL2A1 Antibodies); COL1A1 (show COL1A1 Antibodies) and IMP3 (show IGF2BP3 Antibodies).

  2. DACT2 suppresses papillary thyroid cancer proliferation and metastasis by inhibiting Wnt (show WNT2 Antibodies) signaling.

  3. There was no statistical difference between groups concerning DACT1 (show DACT1 Antibodies) and DACT2 either in promoter hypermethylation or transcript levels. Age was associated with DACT2 promoter hypermethylation, especially over 56 years old.

  4. DACT2 acts as a functional tumor suppressor in colon cancer through inhibiting Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling. Its methylation at early stages of colon carcinogenesis is an independent prognostic factor.

  5. DACT2 suppresses hepatocellular carcinoma by inhibiting Wnt (show WNT2 Antibodies) signaling in human hepatocellular carcinoma cells.

  6. Loss of DACT2 expression is associated with esophageal squamous cell carcinoma.

  7. Reduced expression of DACT2 due to methylation-mediated gene silencing promotes hepatocellular carcinoma progression

  8. Epigenetic regulation of DACT2 is a key component of the Wnt (show WNT2 Antibodies) signalling pathway in human lung cancer.

  9. Hypermethylation of Dact1 (show DACT1 Antibodies) gene is associated with transitional cell carcinomas.

  10. Nuclear beta-catenin (show CTNNB1 Antibodies) was more frequently expressed in non-polypoid growth low grade colorectal neoplasms than in polypoid growth neoplasms.

Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) (DACT2) Antigen Profile

Protein Summary

Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors (By similarity).

Gene names and symbols associated with DACT2

  • dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis) (DACT2) antibody
  • dapper homolog 2, antagonist of beta-catenin (xenopus) (Dact2) antibody
  • dishevelled-binding antagonist of beta-catenin 2 (DACT2) antibody
  • dishevelled-binding antagonist of beta-catenin 2 (Dact2) antibody
  • 2900084M21Rik antibody
  • A630024E20 antibody
  • bA503C24.7 antibody
  • C6orf116 antibody
  • DAPPER2 antibody
  • DPR2 antibody
  • Frd2 antibody
  • RP11-503C24.7 antibody

Protein level used designations for DACT2

dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis) , dapper homolog 2-like , dapper antagonist of catenin 2 , dapper homolog 2 , dapper, antagonist of beta-catenin, homolog 2 , mDpr2 , dapper homolog 2, antagonist of beta-catenin

GENE ID SPECIES
742130 Pan troglodytes
100462224 Pongo abelii
240025 Mus musculus
421561 Gallus gallus
168002 Homo sapiens
308212 Rattus norvegicus
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