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anti-Defensin, alpha 4, Corticostatin (DEFA4) Antibodies

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. Additionally we are shipping Defensin, alpha 4, Corticostatin Kits (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DEFA4 1669 P12838
DEFA4 13238 P28311
DEFA4    
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Top anti-Defensin, alpha 4, Corticostatin Antibodies at antibodies-online.com

Showing 10 out of 29 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry analysis of Defensin alpha 4 Antibody in paraffin-embedded human heart tissue. Western blot analysis of Defensin alpha 4 antibody at a 1/500 dilution. Lane 1: MCF-7 cell lysate. Lane 2: Mouse spleen tissue extract. Lane 3: Rat spleen tissue extract. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
$566.50
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated IHC, ELISA   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB   50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

DEFA4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,


, , , , , , , , , , ,
Mouse (Murine) ,


Rat (Rattus) ,


More Antibodies against Defensin, alpha 4, Corticostatin Interaction Partners

Rhesus Monkey Defensin, alpha 4, Corticostatin (DEFA4) interaction partners

  1. Lys-for-Arg substitutions in rhesus myeloid alpha-defensin improved microbicidal activity against certain bacteria

Human Defensin, alpha 4, Corticostatin (DEFA4) interaction partners

  1. DEFA4 displays antimicrobial activity against E. coli, S. faecalis, and C. albicans.

  2. Results indicate that the gene expression of DEFA 1 (show DEFA1 Antibodies)/3 and 4 was significantly increased in all tumours - except for a significant decrease of DEFA 4 gene expression in pleomorphic adenomas.

  3. DEFA1 (show DEFA1 Antibodies)-3 and DEFA4 mRNA level in peripheral blood cells can be used to identify chronic myeloid leukaemia patients who are at risk of being imatinib-resistant, before initiation of the therapy.

  4. The combination of an increased expression of the antimicrobial peptide (show cAMP Antibodies) DEFA-4, the oncogene (show RAB1A Antibodies) S100-A7, epidermal growth factor (show EGF Antibodies), and tenascin-c (show TNC Antibodies), and a decreased Doc-1 (show CDK2AP1 Antibodies) expression in oral leukoplakia might characterize its potency of malignant transformation.

  5. Crystal structure of HNP-4.

  6. DEFA4 was upregulated in IPF patients with acute exacerbation

Mouse (Murine) Defensin, alpha 4, Corticostatin (DEFA4) interaction partners

  1. MMP-7 (show MMP7 Antibodies)-dependent procryptdin activation in vivo provides mouse Paneth cells with functional peptides for apical secretion into the small intestine lumen

  2. the prosegment of Crp4 inhibits Crp4 bactericidal activity by blocking peptide-mediated perturbation of target cell membranes

  3. Crp4 disulfide arrangement confers essential protection from degradation by this critical activating proteinase, allowing antibacterial action.

  4. cryptdin-1 and cryptdin-4 exhibit circadian oscillation

  5. function of the conserved salt bridge in Crp4 is not linked to bactericidal activity or proteolytic stability of the mature peptide.

  6. CRP4 mediates cGMP/PKG (show PRKG1 Antibodies) stimulation of SM-specific gene expression, and PKG (show PRKG1 Antibodies) plays an important role in regulating the phenotype of VSMCs

  7. Kinetics of Crp4 translocation coupled with peptide-induced vesicle leakage are reported.

  8. Beta-sheet-containing Crp4 induces membrane permeabilization more effectively than disulfide-null Crp4 by translocating and forming transient membrane defects.

  9. Lys-for-Arg replacements in cryptdin 4 attenuated bactericidal activity

Defensin, alpha 4, Corticostatin (DEFA4) Antigen Profile

Protein Summary

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils\; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production.

Gene names and symbols associated with DEFA4

  • defensin, alpha 4, corticostatin (DEFA4) antibody
  • alpha-defensin 2 (MNP2) antibody
  • defensin, alpha, 4 (Defa4) antibody
  • Crp4 antibody
  • DEF4 antibody
  • DEFA4 antibody
  • Defa28 antibody
  • Defcr4 antibody
  • HNP-4 antibody
  • HP-4 antibody
  • HP4 antibody

Protein level used designations for DEFA4

alpha-defensin 4, corticostatin , Paneth cell-specific alpha-defensin 4 , Neutrophil defensin 4 , RMAD-4 , RMAD-6 , neutrophil defensin 6 , corticostatin , defensin, alpha 4, preproprotein , neutrophil defensin 4 , alpha-defensin 4 , alpha-defensin, 28 , defensin related cryptdin 4 , defensin, alpha, 28 , defensin-related cryptdin-4

GENE ID SPECIES
574311 Macaca mulatta
100307026 Equus caballus
574197 Macaca mulatta
1669 Homo sapiens
463971 Pan troglodytes
13238 Mus musculus
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