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Deleted in Liver Cancer 1 (DLC1) ELISA Kits

DLC1 contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Additionally we are shipping DLC1 Antibodies (56) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DLC1 10395 Q96QB1
Anti-Mouse DLC1 DLC1 50768 Q9R0Z9
Anti-Rat DLC1 DLC1 58834  
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Top DLC1 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details

More ELISA Kits for DLC1 Interaction Partners

Human Deleted in Liver Cancer 1 (DLC1) interaction partners

  1. Low expression of DLC1 (show DYNLL1 ELISA Kits) is predictive of poor therapeutic efficiency of fluoropyrimidine and oxaliplatin as adjuvant chemotherapy in gastric cancer.

  2. No significant association of DLC1 (show DYNLL1 ELISA Kits) SNPs with the patients' prognosis was found.

  3. A phosphorylation-mediated molecular switch comprising DLC), TNS3 (show TNS3 ELISA Kits), PTEN and PI3K (show PIK3CA ELISA Kits) controls the spatiotemporal activation of Rac1 and RhoA (show RHOA ELISA Kits), thereby initiating directional cell migration induced by growth factors.

  4. Data suggest BCL2-like 1 (show BCL2L1 ELISA Kits) protein (BCL2L1 (show BCL2L1 ELISA Kits)) and deleted in liver cancer 1 protein (DLC1) as potential druggable targets for specific subsets of gastric cancer (GC) cases.

  5. DLEC1 (show DLEC1 ELISA Kits) mediates tumor-suppressive activities through NF-kappaB (show NFKB1 ELISA Kits) signaling.

  6. Low DLC1 (show DYNLL1 ELISA Kits) expression is associated with cancer.

  7. During early cell spreading, DLC1 (show DYNLL1 ELISA Kits) is preferentially localized at the inner/mature adhesions whereas phosphorylated paxillin (show PXN ELISA Kits) occupies the outer/nascent focal adhesions. In addition, DLC1 (show DYNLL1 ELISA Kits) downregulates paxillin (show PXN ELISA Kits) turnover

  8. Cooperation of DLC1 (show DYNLL1 ELISA Kits) and CDK6 (show CDK6 ELISA Kits) affects breast cancer clinical outcome

  9. DLEC1 (show DLEC1 ELISA Kits) methylation was not associated with the clinicopathological variables of gastric cancer.

  10. Studies indicate that deleted in liver cancer-1 (DLC1) contributes to growth and migratory suppressive effects through GAP-dependent and GAP-independent mechanisms.

Mouse (Murine) Deleted in Liver Cancer 1 (DLC1) interaction partners

  1. studies demonstrate that TNS1 (show TNS1 ELISA Kits) binds to DLC1 and fine-tunes its RhoGAP (show ARHGAP1 ELISA Kits) activity toward RhoA (show RHOA ELISA Kits) and that the TNS1 (show TNS1 ELISA Kits)-DLC1-RhoA (show RHOA ELISA Kits) signaling axis is critical in regulating cellular functions that lead to angiogenesis

  2. Loss of expression of only Dlc1 isoform 2 may be sufficient for the development of thymic tumors and metastasis.

  3. Several genes and biochemical activities collaborate with the inactivation of DLC1 to give rise to cell transformation in MEFs, and the identified genes are relevant to human tumors with low DLC1 expression.

  4. The Dlc1 deficient cells showed altered cytoskeleton structure, increased RhoA (show RHOA ELISA Kits) activity and cellular migration.

  5. DLC-1-/- embryos had defects in the neural tube, brain, heart, and placenta

  6. Our data validate DLC1 as a potent tumor suppressor gene and suggest that its loss creates a dependence on the RhoA (show RHOA ELISA Kits) pathway that may be targeted therapeutically.

DLC1 Antigen Profile

Antigen Summary

This gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins. Aberrant transcription of this gene may be involved in carcinogenesis of the lung, esophagus, and kidney.

Gene names and symbols associated with DLC1

  • deleted in liver cancer 1 (dlc1) antibody
  • deleted in liver cancer 1 (DLC1) antibody
  • deleted in liver cancer 1 (Dlc1) antibody
  • deleted in lung and esophageal cancer 1 (DLEC1) antibody
  • A730069N07Rik antibody
  • Arhgap7 antibody
  • Dlc-1 antibody
  • DLC1 antibody
  • F56 antibody
  • HP antibody
  • p122-RhoGAP antibody
  • RhoGAP antibody
  • rhogap7 antibody
  • StARD12 antibody

Protein level used designations for DLC1

deleted in liver cancer 1 , rho GTPase-activating protein 7-like , Rho-GTPase-activating protein 7 , START domain-containing protein 12 , StAR-related lipid transfer (START) domain containing 12 , deleted in liver cancer 1 protein , deleted in liver cancer 1 variant 2 , rho GTPase-activating protein 7 , rho-type GTPase-activating protein 7 , p122-RhoGAP , stAR-related lipid transfer protein 12 , deleted in liver cancer 1 protein homolog , dlc-1 , rho GTPase activating protein 7 , stARD12 , Deleted in liver cancer 1 protein homolog , Rho-type GTPase-activating protein 7 , DLC-1 , deleted in lung and esophageal cancer 1 transcript varient 2 , deleted in lung and esophageal cancer protein 1

GENE ID SPECIES
431800 Xenopus laevis
422740 Gallus gallus
464001 Pan troglodytes
700630 Macaca mulatta
100022416 Monodelphis domestica
100052317 Equus caballus
100352546 Oryctolagus cuniculus
100470350 Ailuropoda melanoleuca
100488460 Xenopus (Silurana) tropicalis
100456847 Pongo abelii
100553915 Anolis carolinensis
100598737 Nomascus leucogenys
10395 Homo sapiens
50768 Mus musculus
58834 Rattus norvegicus
511433 Bos taurus
475607 Canis lupus familiaris
9940 Homo sapiens
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