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anti-Developmental Pluripotency Associated 3 (DPPA3) Antibodies

DPPA3 encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. Additionally we are shipping DPPA3 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DPPA3 359787 Q6W0C5
DPPA3 73708 Q8QZY3
DPPA3 297576 Q6IMK0
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Top anti-DPPA3 Antibodies at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-Stella/DPPA3 Polyclonal Antibody, Unconjugated (ABIN1713577) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 14 to 21 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p) 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 3 to 4 Days
$186.35
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 11 to 16 Days
$264.29
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 6 to 11 Days
$535.71
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 6 Days
$359.70
Details

DPPA3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
, ,

Mouse (Murine)
,

Rat (Rattus)


Top referenced anti-DPPA3 Antibodies

  1. Human Polyclonal DPPA3 Primary Antibody for WB - ABIN2476603 : Bowles, Teasdale, James, Koopman: Dppa3 is a marker of pluripotency and has a human homologue that is expressed in germ cell tumours. in Cytogenetic and genome research 2003 (PubMed)

More Antibodies against DPPA3 Interaction Partners

Cow (Bovine) Developmental Pluripotency Associated 3 (DPPA3) interaction partners

  1. DPPA3 is a maternal factor (show ZAR1 Antibodies) important for correct epigenetic remodeling and normal embryonic development in cattle, indicating that the role of DPPA3 during early development is conserved between species.

Human Developmental Pluripotency Associated 3 (DPPA3) interaction partners

  1. Data suggest enforced expression of Stella into normal cells induces not only global DNA demethylation but also neoplastic transformation and increases metastatic ability; these changes involve altered regulation of neoplastic gene expression.

  2. Considering that impaired DNA methylation (show HELLS Antibodies) profiles are associated with various developmental or disease phenomena, Stella may be a powerful tool with which to study the biological effects of global DNA hypomethylation

  3. a role for STELLA in facilitating germline and endodermal differentiation of human ES cells

  4. human adult tissue-specific transcripts originate via retrotransposition of the pluripotent cell-specific gene, Dppa3

  5. These results demonstrate that PGC7/Stella is indispensable for the maintenance of methylation involved in epigenetic reprogramming after fertilization.

  6. In mice, a targeted mutation results in reduced female fertility and (show MTA2 Antibodies)may function as a mammalian maternal effect gene.

  7. In mice, knockout experiments show this gene may be a maternal factor (show ZAR1 Antibodies) in cleavage stage embryogenesis.

Mouse (Murine) Developmental Pluripotency Associated 3 (DPPA3) interaction partners

  1. In-depth transcriptome analysis of this mESC state reveals Dppa3 as a direct downstream target of Tbx3 (show TBX3 Antibodies).We show that Tbx3 (show TBX3 Antibodies), a downstream target of Wnt (show WNT2 Antibodies) signaling, fine tunes these divergent roles of Wnt (show WNT2 Antibodies) signaling in mESCs

  2. Dppa3 has a critical role in generation of fully reprogrammed iPS (show SLC27A4 Antibodies) cells and maintenance of Dlk1 (show DLK1 Antibodies)-Dio3 (show DIO3 Antibodies) imprinting

  3. Stella protects maternal chromosomes from aberrant epigenetic modifications to ensure early embryogenesis.

  4. Chromocenter formation is impaired in Stella-null embryos.

  5. we propose that Dppa3 is involved in the Tet-mediated active demethylation process during reprogramming of primordial germ cells.

  6. PGC7 protects 5mC from Tet3 (show TET3 Antibodies)-mediated conversion to 5hmC by binding to maternal chromatin containing dimethylated histone H3 (show HIST3H3 Antibodies) lysine 9 (H3K9me2) in mice

  7. These Dppa3-MCM strains offer valuable opportunities to explore gene function in both loss-of-function and gain-of-function experiments at a variety of time points during germ cell development.

  8. DPPA3 is an essential factor for the production of functional oocytes through transcriptional repression and chromatin condensation.

  9. Data show that STELLA was found in both the nucleus and cytoplasm in a variety of cell types, both within and outside of the putative primordial germ cells (PGCs)trajectory.

  10. Data show that Stella is specifically expressed in preimplantation embryos and in the germline.

DPPA3 Antigen Profile

Protein Summary

This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance of cell pluripotentiality. In humans, related intronless loci are located on chromosomes 14 and X.

Gene names and symbols associated with DPPA3

  • developmental pluripotency associated 3 (DPPA3) antibody
  • developmental pluripotency-associated 3 (Dppa3) antibody
  • 2410075G02Rik antibody
  • PCG7 antibody
  • PGC7 antibody
  • Stella antibody

Protein level used designations for DPPA3

developmental pluripotency-associated protein 3 , stella , stella-related protein , developmental pluripotency associated 3 , compaction-associated protein 1 , primordial germ cell 7 , primordial germ cell protein 7

GENE ID SPECIES
616433 Bos taurus
748273 Pan troglodytes
359787 Homo sapiens
73708 Mus musculus
297576 Rattus norvegicus
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