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anti-Diacylglycerol Kinase, alpha 80kDa (DGKA) Antibodies

The protein encoded by DGKA belongs to the eukaryotic diacylglycerol kinase family. Additionally we are shipping DGKA Proteins (12) and DGKA Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DGKA 13139 O88673
DGKA 140866 P51556
DGKA 1606 P23743
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Top anti-DGKA Antibodies at antibodies-online.com

Showing 10 out of 105 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using DGKA Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-DGKA Antibody (C-term) (ABIN392729) in HL60 cell line lysates (35 µg/lane). DGKA (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-DGKA Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DGKA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DGKA. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DGKA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DGKA. Flow cytometric Analysis of Jurkat cells, using anti-DGKA antibody (ABIN2455378), (Red), compared to a nonspecific negative control antibody, (Blue). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-DGKA mouse monoclonal antibody. (ABIN2455396) HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DGKA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DGKA. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DGKA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DGKA. Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-DGKA mouse monoclonal antibody. (ABIN2455395) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DGKA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DGKA. Flow cytometric Analysis of Jurkat cells, using anti-DGKA antibody (ABIN2455398), (Red), compared to a nonspecific negative control antibody, (Blue). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DGKA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DGKA. 100 μL Log in to see 2 to 3 Days
$423.50
Details

DGKA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


Rat (Rattus)
,
,
Human , , ,
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Top referenced anti-DGKA Antibodies

  1. Human Polyclonal DGKA Primary Antibody for EIA, IHC (p) - ABIN360612 : Hart, Zhou, Champagne, Van Dyke, Rao, Pettenati: Assignment of the human diacylglycerol kinase gene (DAGK) to 12q13.3 using fluorescence in situ hybridization analysis. in Genomics 1994 (PubMed)
    Show all 2 references for ABIN360612

More Antibodies against DGKA Interaction Partners

Mouse (Murine) Diacylglycerol Kinase, alpha 80kDa (DGKA) interaction partners

  1. Our studies demonstrate that PKD1 (show PKD1 Antibodies)/2 is a key regulator of MVB maturation and exosome secretion, and constitutes a mediator of the DGK alpha effect on MVB secretory traffic.

  2. Diacylglycerol kinase alpha establishes T cell polarity by shaping diacylglycerol accumulation at the immunological synapse.

  3. Ovalbumin (show OVA Antibodies)-induced airway inflammation was inhibited after DGKalpha DNA vaccine administation.

  4. Data indicate that combined deletion of dgkzeta (show DGKZ Antibodies) and dgkalpha markedly enhances T-cell responses.

  5. The data strongly supported a role for FoxO (show FOXO3 Antibodies) proteins in promoting high diacylglycerol kinase alpha levels and indicate a mechanism by which diacylglycerol kinase alpha function is downregulated during productive T cell responses.

  6. results suggest that the globular form of adiponectin (show ADIPOQ Antibodies)-induced generation of reactive oxygen species and nitric oxide involves diacylglycerol kinase alpha

  7. DAG kinases (DGKs) alpha and zeta, which terminate DAG-mediated signaling, synergistically inhibit TCR-induced mTOR (show FRAP1 Antibodies) activation by inhibiting the Ras-Mek1 (show MAP2K1 Antibodies)/2-Erk (show EPHB2 Antibodies)/12 pathway

  8. A role for DGK alpha in T cell activation is confirmed by the rapid DGK alpha translocation to the membrane fraction, together with the increase in enzyme activity that follows T cell activation in vivo.

  9. regulated by pi 3 (show PI3 Antibodies)-kinase activation products

  10. Diacylglycerol kinase alpha is an anergy-associated molecule that negatively regulates Ras in anergic T cells.

Human Diacylglycerol Kinase, alpha 80kDa (DGKA) interaction partners

  1. An abandoned compound that also inhibits serotonin receptors may have more translational potential as a DGKa inhibitor, but more potent and specific DGKa inhibitors are sorely needed

  2. Decreased DNA methylation (show HELLS Antibodies) at this enhancer enables recruitment of the profibrotic transcription factor early growth response 1 (EGR1 (show EGR1 Antibodies)) and facilitates radiation-induced DGKA transcription in cells from patients later developing fibrosis.

  3. These data indicates the existence of a SDF-1alpha induced DGKalpha - atypical PKC - beta1 integrin signaling pathway, which is essential for matrix invasion of carcinoma cells.

  4. DGKalpha generates phosphatidic acid to drive its own recruitment to tubular recycling endosomes via its interaction with MICAL-L1 (show MICALL1 Antibodies)

  5. High diacylglycerol kinase alpha expression is associated with glioblastoma.

  6. DGKalpha is involved in hepatocellular carcinoma progression by activation of the MAPK (show MAPK1 Antibodies) pathway.

  7. DGK-alpha was more highly expressed in CD8 (show CD8A Antibodies)-tumor-infiltrating T cellscompared with that in CD8non-tumor kidney-infiltrating lymphocytes.

  8. Antigen-specific CD8 (show CD8A Antibodies)-positive T cells from DGKalpha-deficient transgenic mice show enhanced expansion and increased cytokine production after lymphocytic choriomeningitis virus infection, yet DGK (show DGKB Antibodies)-deficient memory CD8 (show CD8A Antibodies)+ T cells exhibit impaired expansion.

  9. SAP (show APCS Antibodies)-mediated inhibition of DGKalpha sustains diacylglycerol signaling, thereby regulating T cell activation

  10. Diacylglycerol kinase alpha is a key regulator of the polarised secretion of exosomes.

Pig (Porcine) Diacylglycerol Kinase, alpha 80kDa (DGKA) interaction partners

  1. the nucleo-cytoplasmic shuttling of DGKalpha is orchestrated by tyrosine phosphorylation by the Src-activated tyrosine kinase c-Abl

DGKA Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Gene names and symbols associated with DGKA

  • diacylglycerol kinase, alpha 80kDa (DGKA) antibody
  • diacylglycerol kinase, alpha 80kDa (dgka) antibody
  • diacylglycerol kinase, alpha a (dgkaa) antibody
  • diacylglycerol kinase alpha (Tsp_02164) antibody
  • diacylglycerol kinase, alpha (Dgka) antibody
  • 80kDa antibody
  • AW146112 antibody
  • DAGK antibody
  • DAGK1 antibody
  • DGK-alpha antibody
  • dgka antibody
  • zgc:136759 antibody

Protein level used designations for DGKA

diacylglycerol kinase, alpha 80kDa , diacylglycerol kinase alpha , diacylglycerol kinase alpha-like , 80 kDa diacylglycerol kinase , DAG kinase alpha , DGK-alpha , diacylglycerol kinase alpha Flt2-Pr2 , diglyceride kinase alpha , truncated diacylglycerol kinase alpha Flt1-Pr1

GENE ID SPECIES
451976 Pan troglodytes
564739 Danio rerio
710559 Macaca mulatta
724010 Danio rerio
10907457 Trichinella spiralis
100124931 Xenopus (Silurana) tropicalis
100172456 Pongo abelii
100347223 Oryctolagus cuniculus
100380983 Xenopus laevis
100405635 Callithrix jacchus
100593934 Nomascus leucogenys
13139 Mus musculus
140866 Rattus norvegicus
1606 Homo sapiens
506348 Bos taurus
397097 Sus scrofa
474393 Canis lupus familiaris
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