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anti-Dihydropyrimidine Dehydrogenase (DPYD) Antibodies

The protein encoded by DPYD is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Additionally we are shipping DPYD Kits (40) and DPYD Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DPYD 81656 O89000
DPYD 1806 Q12882
DPYD 99586 Q8CHR6
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Top anti-DPYD Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Anti-DPYD antibody, Western blotting WB: MM231 Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to DPYD on HeLa cell (antibody concentration 10 µg/mL). DPYD monoclonal antibody (M01), clone 7D4 Western Blot analysis of DPYD expression in HeLa. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$463.83
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using DPYD antibody. 100 μL Log in to see 9 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Raji B: K562 C: NCI-H929 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image DPYD antibody [N1N2], N-term detects DPYD protein at cytoplasm on H358 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded H358 xenograft. DPYD antibody [N1N2], N-term , dilution: 1:500. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to DPYD on HeLa cell. [antibody concentration 10 ug/ml] DPYD monoclonal antibody (M01), clone 7D4 Western Blot analysis of DPYD expression in HeLa . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (fp), WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details

DPYD Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,


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More Antibodies against DPYD Interaction Partners

Human Dihydropyrimidine Dehydrogenase (DPYD) interaction partners

  1. Results suggest that DPYD c.1129-5923 C>G/hapB3 have limited predictive value for severe toxicity to 5-FU based combination chemotherapy.

  2. oxaliplatin-based chemotherapy increases ERCC1 (show ERCC1 Antibodies) and DPYD expression levels; bevacizumab induces VEGFA (show VEGFA Antibodies) expression in metastatic colorectal cancer

  3. This study demonstrates the clinical validity of combined MIR27A/DPYD screening to identify patients at risk of severe FP-toxicity.

  4. The expression of dihydropyrimidine dehydrogenase and its correlation with survival in stage II/III gastric cancer patients

  5. We propose the gene activity score for translating DPYD genotype into phenotype--{REVIEW}

  6. Demonstrate a correlation between occurrence of DPYD gene variant c.496A>G and KRAS wild type status of colorectal cancer tissue.

  7. Single nucleotide polymorphisms (SNPs) in Dihydropyrimidine Dehydrogenase and UGT1A1 (show UGT1A1 Antibodies) influence fluoropyrimdines and irinotecan adverse events (AEs (show AES Antibodies)).

  8. The relationship between DPD genotype and dihydrouracil/uracil values in the 22 patients of the present study was significant

  9. DPYD variants c.1679T>G and c.1236G>A/HapB3 are clinically relevant predictors of fluoropyrimidine-associated toxicity.

  10. The dihydropyrimidine dehydrogenase and ERCC1 (show ERCC1 Antibodies) expression profile could potentially serve as a useful prognostic biomarker and therapeutic target for surgically resected patients with ampullary carcinoma.

Mouse (Murine) Dihydropyrimidine Dehydrogenase (DPYD) interaction partners

  1. DPD gene expression is regulated first at the mRNA level when the hepatocytes enter the cell cycle. There is little regulation at the translational level. Cell proliferation rate is influences the enzyme activity modification.

Pig (Porcine) Dihydropyrimidine Dehydrogenase (DPYD) interaction partners

  1. Data show that dihydropyrimidine dehydrogenase residue H673 is required for active site closure, while S670 is important for substrate recognition.

DPYD Antigen Profile

Protein Summary

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DPYD

  • dihydropyrimidine dehydrogenase (DPYD) antibody
  • dihydropyrimidine dehydrogenase b (dpydb) antibody
  • dihydropyrimidine dehydrogenase (dpyd) antibody
  • dihydropyrimidine dehydrogenase (EHI_012980) antibody
  • dihydropyrimidine dehydrogenase (AaeL_AAEL014199) antibody
  • dihydropyrimidine dehydrogenase (AaeL_AAEL010204) antibody
  • dihydropyrimidine dehydrogenase (EDI_044620) antibody
  • dihydropyrimidine dehydrogenase (pyd1) antibody
  • dihydropyrimidine dehydrogenase (Dpyd) antibody
  • dihydropyrimidine dehydrogenase (LOC100356889) antibody
  • 14.t00017 antibody
  • AI315208 antibody
  • DDBDRAFT_0189681 antibody
  • DDBDRAFT_0231100 antibody
  • DDB_0189681 antibody
  • DDB_0231100 antibody
  • DHP antibody
  • DHPDHASE antibody
  • DPD antibody
  • dpyd antibody
  • E330028L06Rik antibody
  • zgc:77205 antibody

Protein level used designations for DPYD

DHPDHase , DPD , dihydropyrimidine dehydrogenase [NADP(+)] , dihydrothymine dehydrogenase , dihydrouracil dehydrogenase , dihydropyrimidine dehydrogenase

GENE ID SPECIES
100173131 Pongo abelii
457047 Pan troglodytes
715672 Macaca mulatta
100057177 Equus caballus
405829 Danio rerio
447312 Xenopus laevis
3410647 Entamoeba histolytica HM-1:IMSS
5563876 Aedes aegypti
5573038 Aedes aegypti
5882869 Entamoeba dispar SAW760
8616259 Dictyostelium discoideum AX4
100604410 Nomascus leucogenys
81656 Rattus norvegicus
1806 Homo sapiens
99586 Mus musculus
100727906 Cavia porcellus
397109 Sus scrofa
281124 Bos taurus
479935 Canis lupus familiaris
429083 Gallus gallus
101109311 Ovis aries
100356889 Oryctolagus cuniculus
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