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The protein encoded by DOK5 is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. Additionally we are shipping Docking Protein 5 Antibodies (111) and many more products for this protein.
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IGFBP-5 (show IGFBP5 Proteins) induces its pro-fibrotic effects, at least in part, via DOK5. IGFBP-5 (show IGFBP5 Proteins) and DOK5 are both increased in systemic sclerosis fibroblasts and tissues and may thus be acting in concert to promote fibrosis.
Although preliminary, these data suggest that DOK5 and perhaps several other genes influence the magnitude of amygdala activation during face processing, particularly in those with BD.
identified DOK5 as a novel susceptibility gene for obesity and type 2 diabetes in North Indian subjects
DOK5 expression in human T cells, its genomic structure characterized, and its regulation upon T cell activation has been demonstrated.
IRS5/DOK4 (show DOK4 Proteins) and IRS6/DOK5 represent two new signaling proteins with potential roles in insulin (show INS Proteins) and IGF-1 (show IGF1 Proteins) action
Dok5 is necessary for NT-3 (show NTF3 Proteins) signaling to block TrkC (show NTRK3 Proteins)-induced apoptosis
FOXO3a (show FOXO3 Proteins), the PI3K/PKB (show AKT2 Proteins) downstream substrate, acts as a transcriptional repressor to inhibit the expression of Dok-5.
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.
docking protein 5
, Docking protein 5
, downstream of tyrosine kinase 5
, insulin receptor substrate 6