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Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) Proteins (DPAGT1)

The protein encoded by DPAGT1 is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. Additionally we are shipping Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) Antibodies (51) and Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DPAGT1 13478 P42867
DPAGT1 1798 Q9H3H5
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Top Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
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Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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DPAGT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1) Interaction Partners

Human Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1) interaction partners

  1. Studies show that cells coordinate DPAGT1 expression and protein N-glycosylation with canonical Wnt (show WNT2 Proteins) signaling and E-cadherin (show CDH1 Proteins) adhesion via positive and negative feedback mechanisms.

  2. prominent limb-girdle weakness and minimal craniobulbar symptoms who harbour a novel mutation in DPAGT1

  3. Patients with DPAGT1 CMS (show Cd2ap Proteins) share similar clinical features with patients who have CMS (show Cd2ap Proteins) caused by mutations in GFPT1 (show GFPT1 Proteins), another recently identified CMS (show Cd2ap Proteins) subtype.

  4. Results indicate that the clinical spectrum of dolichyl-phosphate alpha-N-acetylglucosaminyltransferase (DPAGT1)-congenital disorders of glycosylation (CDG) is much broader than appreciated so far.

  5. Data suggest that in oral squamous cell carcinoma (OSCC), dysregulation of canonical Wnt (show WNT2 Proteins) signaling and DPAGT1-dependent N-glycosylation induces CTHRC1 (show CTHRC1 Proteins), thereby driving OSCC cell migration and tumor spread.

  6. suggest that the primary pathogenic mechanism of DPAGT1-associated CMS (show Cd2ap Proteins) is reduced levels of AChRs at the endplate region. This finding demonstrates that impairment of the N-linked glycosylation pathway can lead to the development of CMS (show Cd2ap Proteins)

  7. Overexpression of DPAGT1 in human oral squamous cell carcinoma specimens is linked to aberrant activation of canonical Wnt (show WNT2 Proteins) signaling.

  8. We identify DPAGT1 as a gene in which mutations cause a congenital myasthenic syndrome.

  9. Mutations in DPAGT1 gene is associated with Congenital disorder of glycosylation type Ij.

  10. up-regulation of DPAGT1 transcripts by Wnt3a (show WNT3A Proteins) led to altered N-glycosylation of E-cadherin (show CDH1 Proteins).

Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1) Protein Profile

Protein Summary

The protein encoded by this gene is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. This enzyme belongs to the glycosyltransferase family 4. This protein is an integral membrane protein of the endoplasmic reticulum. The congenital disorder of glycosylation type Ij is caused by mutation in the gene encoding this enzyme.

Gene names and symbols associated with DPAGT1

  • dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (Dpagt1)
  • dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (DPAGT1)
  • ALG7 protein
  • AU021132 protein
  • CDG-Ij protein
  • CDG1J protein
  • CMSTA2 protein
  • D11S366 protein
  • DGPT protein
  • DPAGT protein
  • DPAGT2 protein
  • G1PT protein
  • GNPTA protein
  • GPT protein
  • GTR2 protein
  • UAGT protein
  • UGAT protein

Protein level used designations for DPAGT1

G1PT , N-acetylglucosamine-1-phosphate transferase , UDP-N-acetylglucosamine lysosomal enzyme N-acetylglucosamine phosphotransferase , UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase , dolichyl-phosphate alpha-N-acetylglucosaminephosphotransferase 2 , glcNAc-1-P transferase , GlcNAc-1-P transferase , uridine diphosphate N-acetyl D-glucosamine dolichol phosphate N-acetyl-glucosamine-1 phosphate transferase , UDP-GlcNAc:dolichyl-phosphate N-acetylglucosaminephosphotransferase , dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P tra , dolichyl-phosphate alpha-N-acetylglucosaminyltransferase , GPT , UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase

GENE ID SPECIES
13478 Mus musculus
100689054 Cricetulus griseus
1798 Homo sapiens
537812 Bos taurus
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