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anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) Antibodies

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Additionally we are shipping Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) Kits (28) and Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) Proteins (21) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DDC 13195 O88533
DDC 1644 P20711
DDC 24311 P14173
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Top anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) Antibodies at antibodies-online.com

Showing 10 out of 117 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-DDC Antibody Titration: 5.0ug/mlPositive Control: He... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB DDC Antibody (N-term) (ABIN651727) western blot analysis in mouse live... DDC Antibody (N-term) (ABIN651727) immunohistochemistry analysis in fo... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185393 (0.03µg/ml) staining of Human Kidney lysate (35µg protein i... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit ... Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Ant... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Cow Rabbit Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Cow Rabbit Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 16 Days
$218.90
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details

DDC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,

Human , , , ,
, , , ,
Rat (Rattus) , , , ,

Top referenced anti-Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) Antibodies

  1. Human Monoclonal DDC Primary Antibody for ELISA - ABIN1997115 : Scherer, McPherson, Wasmuth, Marsh: Human dopa decarboxylase: localization to human chromosome 7p11 and characterization of hepatic cDNAs. in Genomics 1992 (PubMed)
    Show all 4 references for ABIN1997115

  2. Human Polyclonal DDC Primary Antibody for WB - ABIN374555 : Voeller: Attention-deficit hyperactivity disorder (ADHD). in Journal of child neurology 2004 (PubMed)

  3. Cow (Bovine) Polyclonal DDC Primary Antibody for WB - ABIN372608 : Berry, Juorio, Li, Boulton: Aromatic L-amino acid decarboxylase: a neglected and misunderstood enzyme. in Neurochemical research 1997 (PubMed)

  4. Human Polyclonal DDC Primary Antibody for IF (p), IHC (p) - ABIN725945 : Hiramoto, Yamate, Kawanishi: Detection of Dopa-positive cells in mouse ovaries in response to ocular exposure to ultraviolet B rays. in Photodermatology, photoimmunology & photomedicine 2014 (PubMed)

  5. Cow (Bovine) Polyclonal DDC Primary Antibody for IHC, WB - ABIN2776802 : Ma, Beuten, Payne, Dupont, Elston, Li: Haplotype analysis indicates an association between the DOPA decarboxylase (DDC) gene and nicotine dependence. in Human molecular genetics 2005 (PubMed)

  6. Human Polyclonal DDC Primary Antibody for WB - ABIN2776803 : Giegling, Moreno-De-Luca, Rujescu, Schneider, Hartmann, Schnabel, Maurer, Möller, Serretti: Dopa decarboxylase and tyrosine hydroxylase gene variants in suicidal behavior. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008 (PubMed)

  7. Human Polyclonal DDC Primary Antibody for FACS, IF - ABIN651727 : Treviño, Yang, French, Hunger, Carroll, Devidas, Willman, Neale, Downing, Raimondi, Pui, Evans, Relling: Germline genomic variants associated with childhood acute lymphoblastic leukemia. in Nature genetics 2009 (PubMed)

More Antibodies against Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) Interaction Partners

Fruit Fly (Drosophila melanogaster) Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) interaction partners

  1. epidermal Ddc induction at pupariation is under the control of an extended genomic region that contains both positive and negative regulatory elements

  2. Broad-Complex protein is required for Ddc activation at eclosion in Drosophila

  3. evidence for a wound response pathway that senses aseptic breaks in the barrier epidermis of Drosophila embryos; a minimal 472-bp Ddc wound response enhancer requires a Grh (show GNRH1 Antibodies) protein binding site and the function of the grh (show GNRH1 Antibodies) gene

  4. The Ddc locus exhibits a complicated pattern of variation apparently due to several evolutionary forces.

  5. The involvement of DDC in a new pathway involved in Drosophila immunity increases the levels of dopamine, which is metabolized to produce reactive quinones that exert an antimicrobial effect on invading bacteria.

Rhesus Monkey Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) interaction partners

  1. Combinatorial expression of tyrosine hydroxylase (TH (show TH Antibodies)), aromatic acid acid decarboxylase (AADC), and the brain-specific (show CALY Antibodies) isoform of the vesicular monoamine transporter (show Slc18a2 Antibodies), VMAT2 (show Slc18a2 Antibodies).

Zebrafish Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) interaction partners

  1. Loss of Ddc appears to result in similar phenotypes as that of ADCC deficiency, thus zebrafish could be a good model for investigating pathogenetic mechanisms of AADC deficiency in children.

Mouse (Murine) Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) interaction partners

  1. The data show that endothelial AADC plays an important role in cardiac synthesis of 5-HT and possibly in 5-HT-dependent regulation of nitric oxide generation.

  2. Mash1 (show ASCL1 Antibodies) plays an important role in regulating the expression of AADC in type III cells in taste buds.

  3. evidence for PKGIalpha-dependent phosphorylation and activation of neuronal AAAD (show AADAC Antibodies) in vitro, and introduce AAAD (show AADAC Antibodies) as a putative PKGIalpha substrate.

  4. Data suggest a possible participation of aromatic L-amino acid decarboxylase (AADC) in the regulation of catecholamine biosynthesis in stellate ganglia of repeatedly stressed mice.

  5. Results suggest that AADC expression begins at early stages of taste bud cell differentiation, and biogenic amines may act on taste bud differentiation of tongue epithelial cells, and further may regulate innervation of taste bud progenitor cells.

  6. analysis of Ddc redefines the imprinted Grb10 (show GRB10 Antibodies) domain on mouse proximal chromosome 11 and identifies Ddc_exon1a as the first example of a heart-specific imprinted gene

  7. the fact that renal DDC inversely correlated with renal sodium reabsorption suggest that renal and intestinal gender dimorphism in DDC could be related to sex-related differences in sodium balance observed between males and females

Human Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) interaction partners

  1. The data showed that L-DOPA decarboxylase constitutes a highly promising molecular marker for renal cell carcinoma (show MOK Antibodies).

  2. gene study of 987 BPD (show MOD(MDG4) Antibodies) cases and 1110 healthy controls found an association between BPD (show MOD(MDG4) Antibodies) [ borderline personality disorder ]and single nucleotide polymorphism rs12718541 in the dopa decarboxylase gene

  3. Results revealed the general picture of structural and/or functional effects of each DDC mutation linked to AADC deficiency mutations and help to guide therapeutic decision and prevent inappropriate use of treatment regiments.

  4. A novel homozygous DDC variant in syndromic intellectual disability patients, c.1123C>T, resulting in p.Arg375Cys missense substitution.

  5. Results indicate that miR (show MLXIP Antibodies)-145 has the ability to regulate DDC mRNA expression and potentially this occurs by recognizing its mRNA as a target.

  6. Our results suggest that DDC may be a genetic modifier of the l-dopa response in Parkinson's disease

  7. assessed variants in four genes, DDC (rs3837091 and rs3735273), DRD2 (show DRD2 Antibodies) (rs1800496, rs1801028, and rs1799732), DRD4 (show DRD4 Antibodies) (rs4646984 and rs4646983), and COMT (show COMT Antibodies) (rs165599 and rs740603) in Indian ADHD subjects with comorbid attributes

  8. 8 SNPs in DDC gene showed significant associations with MaxDrinks.

  9. Common allelic variants in the DDC gene may be involved in autism susceptibility.

  10. The data of this study confirm histidine decarboxylase (show HDC Antibodies) deficiency as a rare cause of TS and identify HA-DA interactions in the basal ganglia as an important locus of pathology.

Pig (Porcine) Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) interaction partners

  1. The unusual oxygen-consuming oxidative deamination reaction catalyzed by the pyridoxal 5'-phosphate (PLP (show PLP1 Antibodies)) enzyme DOPA decarboxylase (DDC) was here investigated.

Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) Antigen Profile

Protein Summary

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with DDC

  • Dopa decarboxylase (Ddc) antibody
  • alpha methyl dopa-resistant (amd) antibody
  • dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC) antibody
  • dopa decarboxylase (aromatic L-amino acid decarboxylase) (ddc) antibody
  • dopa decarboxylase (Ddc) antibody
  • Dopa-decarboxylase (Dvir\\Ddc) antibody
  • dopa decarboxylase (ddc) antibody
  • dopa decarboxylase (aromatic L-amino acid decarboxylase) (Ddc) antibody
  • 5-HT antibody
  • Aadc antibody
  • AMD-r antibody
  • CG10501 antibody
  • CG10697 antibody
  • CG17345 antibody
  • Ddc antibody
  • DdcDm antibody
  • DdcDv antibody
  • Dmel\\CG10501 antibody
  • Dmel\\CG10697 antibody
  • Dvir\\GJ17995 antibody
  • dvir_GLEANR_2561 antibody
  • fAMD antibody
  • fDDC antibody
  • GJ17995 antibody
  • l(2)37Bk antibody
  • l(2)37Bl antibody
  • l(2)37Ch antibody
  • l(2)amd antibody
  • l(2)amd alpha-methyldopa hypersensitive antibody
  • l(2)amd[H] antibody
  • l(2)k02104 antibody
  • wu:fa56d05 antibody
  • wu:fd59h03 antibody
  • wu:fk20h01 antibody
  • X04695 antibody
  • zgc:65801 antibody
  • zgc:76929 antibody

Protein level used designations for DDC

3,4-Dihydroxyphenylalanine decarboxylase , CG10697-PB , CG10697-PC , CG10697-PD , Ddc-PB , Ddc-PC , Ddc-PD , aromatic L-amino acid decarboxylase , dopa decarboxylase , dopa-decarboxylase , dopadecarboxylase , dopamine decarboxylase , transcription unit No. 3 , CG10501-PA , CG10501-PB , DHPAA synthase , alpha methyl dopa , alpha-methotrexate deficient , alpha-methyl dopa resistant , amd-PA , amd-PB , transcription unit No. 1 , dopa decarboxylase (aromatic L-amino acid decarboxylase) , aromatic-L-amino-acid decarboxylase , Aromatic-L-amino-acid decarboxylase , Ddc-PA , Dvir\\Ddc-PA , Dvir\\GJ17995-PA , GJ17995-PA , aromatic-L-amino-acid decarboxylase-like , aromatic-L-amino acid decarboxylase , aromatic amino acid decarboxylase , AADC , L-aromatic dopa decarboxylase , L-Dopa decarboxylase

GENE ID SPECIES
35190 Drosophila melanogaster
35188 Drosophila melanogaster
420947 Gallus gallus
463409 Pan troglodytes
496742 Xenopus (Silurana) tropicalis
662962 Tribolium castaneum
693677 Macaca mulatta
750094 Pan troglodytes
6634251 Drosophila virilis
100301599 Oryzias latipes
100402255 Callithrix jacchus
100475392 Ailuropoda melanoleuca
100542576 Meleagris gallopavo
100564794 Anolis carolinensis
100597933 Nomascus leucogenys
100135516 Cavia porcellus
406651 Danio rerio
13195 Mus musculus
280762 Bos taurus
1644 Homo sapiens
396857 Sus scrofa
24311 Rattus norvegicus
100126640 Xenopus laevis
606852 Canis lupus familiaris
101106765 Ovis aries
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