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anti-Dopachrome Tautomerase (DCT) Antibodies

Involved in regulating eumelanin and phaeomelanin levels. Additionally we are shipping DCT Kits (36) and DCT Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCT 1638 P40126
DCT 13190 P29812
DCT 290484  
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Top anti-DCT Antibodies at antibodies-online.com

Showing 10 out of 98 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of DCT Antibody (N-term) (ABIN653914) in A375 cell line lysates (35 µg/lane). DCT (arrow) was detected using the purified polyclonal antibody. DCT Antibody (N-term) (ABIN653914) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of DCT Antibody (N-term) (ABIN652717) in K562, A375, Ramos cell line lysates (35 µg/lane). DCT (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with DCT Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Formalin fixed, paraffin embedded breast carcinoma stained with DCT Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of DCT Antibody (N-term) in A375 cell line lysates (35ug/lane). DCT (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of DCT Antibody  in NCI-H460 cell line lysates (35ug/lane). This demonstrates the DCT antibody detected the DCT protein (arrow) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of DCT Antibody (N-term) in A375 cell line lysates (35ug/lane). DCT (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from K562 cells, using DCT Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using DCT Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-Dct  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Mouse Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB Anti-DCT antibody IHC staining of human skin, melanocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959307 concentration 5 ug/ml. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

DCT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , ,
Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-DCT Antibodies

  1. Human Polyclonal DCT Primary Antibody for EIA, WB - ABIN955410 : Sendoel, Kohler, Fellmann, Lowe, Hengartner: HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase. in Nature 2010 (PubMed)
    Show all 5 references for ABIN955410

  2. Human Polyclonal DCT Primary Antibody for FACS, IHC (p) - ABIN652717 : Nishihira, Fujinaga, Kuriyama, Suzuki, Sugimoto, Nakagawa, Tanaka, Sakai: Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation. in Biochemical and biophysical research communications 1998 (PubMed)

  3. Human Polyclonal DCT Primary Antibody for IHC (p), WB - ABIN653914 : Sugimoto, Taniguchi, Nakagawa, Tanaka, Suzuki, Nishihira: Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 A resolution. in Biochemistry 1999 (PubMed)

  4. Human Polyclonal DCT Primary Antibody for IF, ELISA - ABIN1534998 : Cassady, Sturm: Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA. in Gene 1994 (PubMed)

More Antibodies against DCT Interaction Partners

Human Dopachrome Tautomerase (DCT) interaction partners

  1. The effect of DCT on UVR DNA damage responses and survival pathways in melanocytes was examined by knockdown experiments using melanoma cells, neonatal melanoblasts in monoculture and in co-culture with keratinocytes.

  2. Report dopachrome tautomerase expression in mealanocytic tumors.

  3. The results suggested that the miRNAs may be involved in MITF (show MITF Antibodies) regulation of TYR (show TYR Antibodies), TYRP1 (show TYRP1 Antibodies) and TYRP2, which provides a new clue for understanding the role of miRNAs in melanocyte dysfunctional disease.

  4. Data suggest that macrophage migration inhibitory factor (MIF (show MIF Antibodies)) and d-dopachrome tautomerase (show DDT Antibodies) (d-DT) act cooperatively to inhibit steady-state phosphorylation and activation of AMPK (show PRKAA1 Antibodies) in LKB1 (show STK11 Antibodies) wild type and LKB1 (show STK11 Antibodies) mutant non-small cell lung carcinomas cells.

  5. human TRP2 counteracts apoptotic cell death induction, possibly by means of its L-dopachrome tautomerase activity, and negatively affects the p53 (show TP53 Antibodies) pathway

  6. Trp2 SNP2 allele is a risk factor for the development and severity of degenerative disc disease in a Chinese Han population.

  7. Data suggest that OTX2 (show OTX2 Antibodies) may regulate retinal pigment epithelium (RPE (show RPE Antibodies))-specific target genes, such as DOPAchrome tautomerase (DCT), thereby maintaining the homeostasis of RPE (show RPE Antibodies).

  8. Because TRP-2(181-190) overlaps with the known HLA-A*0201-presented epitope TRP-2(180-188), an 11mer peptide encompassing both epitopes might be of specific value for vaccination of a broad population of melanoma patients.

  9. Transgenic Dct regulates neural progenitor cell proliferation in a mouse model.

  10. No genetic susceptibility or increased risk attributed to the tyrosinase (show TYR Antibodies) gene family in Vogt-Koyanagi-Harada disease in Japanese.

Mouse (Murine) Dopachrome Tautomerase (DCT) interaction partners

  1. the slaty mutant melanocytes seem to be more sensitive to ultraviolet rays and oxidative stress than black melanocytes.

  2. A novel murine model of vitiligo (show MITF Antibodies) is established by sequential prime/boost immunizations into the hind footpad and tail dermis with tyrosinase-related protein 2 (TRP2)-180 (SVYDFFVWL) peptide.

  3. study indicates that tumor antigen (TRP2) expressed in MCMV induces a strong and long-lasting anti-melanoma effect through an antibody-dependent mechanism

  4. Vaccine formulations with synthetic long peptides for treating B16F10 skin melanoma fails to elicit strong CD8 (show CD8A Antibodies) T cell responses to self-differentiation antigens TRP-2 and gp100 (show PMEL Antibodies).

  5. level of gene targeting was not improved by the DSB induction, indicating a limited capacity of I-SceI to mediate homologous recombination at the Dct locus

  6. Recombinant dopachrome tautomerase was expressed and purified, without its carboxy-terminal transmembrane region. Analysis of dopachrome tautomerase tryptic peptides by MALDI-TOF/TOF (show FEZF2 Antibodies) determined N-glycosylation as a primary post-translational modification.

  7. Dopachrome tautomerase inactivation elevates the level of ROS (show ROS1 Antibodies), increases the numbers of sunburn cells and apoptotic cells, and decreases the amount of eumelanin in the epidermis upon exposure to chronic UVA radiation

  8. the TRP-2 polypeptide folds in the endoplasmic reticulum (ER) in the presence of calnexin (show CANX Antibodies), until it reaches a dithiothreitol-resistant conformation enabling its ER exit to the Golgi

  9. Results describe the generation of a knockout of the dopachrome tautomerase gene in mice with effects restricted to pigment production and coat color.

  10. We found that ionophore monensin (Mon (show TRIM33 Antibodies)) and the quaternary amine chloroquine (CQ) discriminate between the traffic routes of TRP-2 and TRP-1 (show TRPC1 Antibodies)

DCT Antigen Profile

Protein Summary

Involved in regulating eumelanin and phaeomelanin levels.

Gene names and symbols associated with DCT

  • dopachrome tautomerase (dct) antibody
  • dopachrome tautomerase (DCT) antibody
  • dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) (dct) antibody
  • dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) (DCT) antibody
  • dopachrome tautomerase (Dct) antibody
  • dopachrome tautomerase-like (LOC100353923) antibody
  • transfer RNA proline 2 (anticodon AGG) (TRNAP2) antibody
  • transient receptor potential cation channel, subfamily C, member 2, pseudogene (Trpc2) antibody
  • DT antibody
  • RGD1564975 antibody
  • slaty antibody
  • slt antibody
  • TRNP1 antibody
  • TRP-2 antibody
  • TRP2 antibody
  • Trrp2 antibody
  • Tyrp-2 antibody
  • Tyrp2 antibody

Protein level used designations for DCT

dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) , L-dopachrome tautomerase-like , DT , L-dopachrome Delta-isomerase , L-dopachrome tautomerase , TRP2 , dopachrome delta-isomerase , tyrosinase-related protein 2 , tyrosine-related protein 2 , SLATY locus protein , tyrosinase-related protein-2 , TRP-2 , dopachrome delta isomerase , tyrosinase related protein 2 , rTrp2 , short transient receptor potential channel 2 , transient receptor protein 2

GENE ID SPECIES
549915 Xenopus (Silurana) tropicalis
694577 Macaca mulatta
100058776 Equus caballus
100230498 Taeniopygia guttata
100381161 Xenopus laevis
100389709 Callithrix jacchus
100438537 Pongo abelii
100595345 Nomascus leucogenys
1638 Homo sapiens
13190 Mus musculus
290484 Rattus norvegicus
574066 Sus scrofa
100718804 Cavia porcellus
280761 Bos taurus
485520 Canis lupus familiaris
100170232 Ovis aries
395775 Gallus gallus
100353923 Oryctolagus cuniculus
7218 Homo sapiens
64573 Rattus norvegicus
Selected quality suppliers for anti-DCT (DCT) Antibodies
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