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DRD3 encodes the D3 subtype of the five (D1-D5) dopamine receptors. Additionally we are shipping Dopamine Receptor D3 Antibodies (65) and Dopamine Receptor D3 Kits (35) and many more products for this protein.
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The combination of MTHFR (show MTHFR Proteins), DRD3 and MDR1 polymorphisms associated with a slow ATV (show NBN Proteins) metabolizer phenotype
The DRD3 (rs6280) polymorphism influences younger Parkinson disease age of onset in the US Caucasian population.
A significant positive correlation was found between the DRD3 mRNA level and the score of the excited factor in patients with schizophrenia/schizophreniform disorder.
Ammonia induced autophagy by MTOR (show FRAP1 Proteins) is mediated by DRD3.
Drd3 palmitoylation acts as a molecular switch for Drd3-biased signaling via a GIPC1 (show GIPC1 Proteins)-dependent route, which is likely to affect the mode of action of antipsychotic drugs.
used site-directed mutagenesis to identify key residues involved in D3 receptor signaling function
Review concludes that striatum abnormalities in autism are associated with repetitive and stereotyped behavior in autism and may be related to DRD3 polymorphisms
Study found a significant association with disordered gambling and rs167771 (DRD3) and with rs381572 (CAMK2D (show CAMK2D Proteins)) in humans
We did not find evidence of association between the other four SNPs (rs167771 and rs324029 in DRD3, rs8076005 and rs2066713 in SCL6A4) and Type 2 Diabetes Mellitus.
Combined genetic polymorphisms related to dopamine neurotransmission, COMT (show COMT Proteins) Val158Met and DRD3 Ser9Gly, might influence executive function in schizophrenia.
Alcohol enhances the psychostimulant and conditioning effects of mephedrone in adolescent mice; postulation of unique roles of D3 receptors and BDNF (show BDNF Proteins) in place preference acquisition
Results suggest that the dopamine D3 receptor is centrally involved in the etiology of adult anxiety- and depression-related behaviors that arise from repeated stressful experiences during childhood.
D3R modulates GABAA receptors function in striatum: chronic blockade of D3R increases alpha6 subunit expression and induces insensitivity to the anxiolytic effect of diazepam
The dopamine receptor D1 (show DRD1 Proteins) but not the D3 is also critical for morphine-induced BDNF (show BDNF Proteins) expression.
Study identified a unique role for Npas2 (show NPAS2 Proteins) in the regulation of cocaine reward and dopamine Drd3 receptor expression
D5 regulate CD4 (show CD4 Proteins)(+)T-cell activation and differentiation by modulating ERK (show EPHB2 Proteins) activation and cAMP production.
This study demonstrated that Low dose pramipexole causes D3 receptor-independent reduction of locomotion and responding for a conditioned reinforce/
D3R deficiency results in anxiety-like and depressive-like symptoms that cannot be attributed to motor dysfunction.
This study demonstrated that dopamine D3 receptor is necessary for ethanol consumption in mice.
Our data suggest that the D3 receptor modulates the mu opioid receptor (show OPRM1 Proteins) system in the spinal cord, and that a dysfunction of the D3 receptor can induce a morphine-resistant state.
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
D(3) dopamine receptor
, dopamine receptor D3
, dopamine receptor 3
, dopamine D3 receptor
, dopaminergic receptor D3
, essential tremor 1
, D3 receptor