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Activates the Jnk signaling pathway. Additionally we are shipping DUSP22 Proteins (8) and many more products for this protein.
Showing 10 out of 81 products:
Human Monoclonal DUSP22 Primary Antibody for RNAi, ELISA - ABIN566057
Li, Fu, Chen, Tan: JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration. in The Journal of biological chemistry 2010
Show all 2 Pubmed References
findings connect NOTCH1 (show NOTCH1 Antibodies), DUSP22, and CCL19 (show CCL19 Antibodies)-driven chemotaxis within a single functional network, suggesting that modulation of the homing process may provide a relevant contribution to the unfavorable prognosis associated with NOTCH1 (show NOTCH1 Antibodies) mutations in CLL.
findings suggest that CCR8 (show CCR8 Antibodies) expression in ALCL is more closely related to the presence of DUSP22 rearrangements than to cutaneous involvement and that the function of CCR8 (show CCR8 Antibodies) may extend beyond its skin-homing properties in this disease
Studies suggest that the presence of dual specificity phosphatase 22 (DUSP22) and p63 (show RPE65 Antibodies) tumor suppressor protein (show TP53 Antibodies) (TP63 (show TP63 Antibodies)) rearrangements might be useful to support a diagnosis of anaplastic lymphoma kinase (ALK (show ALK Antibodies))-negative anaplastic large cell lymphoma (ALCL).
Report morphologic features of ALK (show ALK Antibodies)-negative anaplastic large cell lymphomas with DUSP22 gene rearrangements.
Reduced DUSP22 expression was found in colorectal cancer specimens. Low expression level of DUSP22 in stage IV patients had a poor survival outcome
The structure illuminates the molecular basis for substrate binding and may also facilitate the structure-assisted development of DUSP22 inhibitors.
study identified presence of promoter hypermethylation of the DUSP22 gene in Alzheimer's disease(AD); DUSP22 is a likely candidate gene for involvement in the pathogenesis of AD since it inhibits PKA activity and thereby determines TAU phosphorylation status and CREB (show CREB1 Antibodies) signaling
Biallelic rearrangements of DUSP22 is found in CD30 (show TNFRSF8 Antibodies)-positive T-cell lymphoproliferative disorders.
Firefighters had a higher prevalence of dual specificity phosphatase 22-promoter hypomethylation in blood DNA (P = 0.03) and the extent of hypomethylation correlated with duration of firefighting service (P = 0.04) but not with age.
Data show that t(6;7)(p25.3;q32.3) was associated with down-regulation of DUSP22 and up-regulation of MIR29 microRNAs on 7q32.3.
cloning and characterization of JKAP, a positive regulator of the JNK (show MAPK8 Antibodies) pathway
DSP2 acts as a negative regulator of the IL-6 (show IL6 Antibodies)/LIF (show LIF Antibodies)/STAT3 (show STAT3 Antibodies)-mediated signaling pathway.
Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK) (By similarity).
dual specificity phosphatase 22
, dual specificity protein phosphatase 22-A
, dual specificity protein phosphatase 22
, dual specificity phosphatase 22 like
, dual specificity protein phosphatase 22-B
, JNK-stimulating phosphatase 1
, JNK-stimulatory phosphatase-1
, MAP kinase phosphatase x
, homolog of mouse dual specificity phosphatase LMW-DSP2
, low molecular weight dual specificity phosphatase 2
, mitogen-activated protein kinase phosphatase x