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anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) Antibodies

Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Additionally we are shipping EF-Hand Calcium Binding Domain 4B Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EFCAB4B 84766 Q9BSW2
EFCAB4B 381812 Q3UP38
EFCAB4B    
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Top anti-EF-Hand Calcium Binding Domain 4B Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-EFCAB4B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-EFCAB4B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of EFCAB4B in mouse kidney tissue lysate with EFCAB4B antibody at 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB EFCAB4B Antibody (N-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the EFCAB4B antibody detected the EFCAB4B protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB EFCAB4B antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

EFCAB4B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
,

, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-EF-Hand Calcium Binding Domain 4B Antibodies

  1. Human Polyclonal EFCAB4B Primary Antibody for EIA, WB - ABIN783785 : Srikanth, Jung, Kim, Souda, Whitelegge, Gwack: A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells. in Nature cell biology 2010 (PubMed)
    Show all 2 references for ABIN783785

  2. Human Polyclonal EFCAB4B Primary Antibody for WB - ABIN2783361 : Lim, Hao, Shaw, Patel, Szabó, Rual, Fisk, Li, Smolyar, Hill, Barabási, Vidal, Zoghbi: A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. in Cell 2006 (PubMed)

More Antibodies against EF-Hand Calcium Binding Domain 4B Interaction Partners

Human EF-Hand Calcium Binding Domain 4B (EFCAB4B) interaction partners

  1. endothelial cells contain a long variant of CRACR2A which is an EF-hand-containing Rab (show HRB Antibodies) protein that lacks impact on CRAC channels

  2. CRACR2A interacts directly with Orai1 (show ORAI1 Antibodies) and STIM1 (show STIM1 Antibodies), forming a ternary complex that dissociates at elevated Ca(2 (show CA2 Antibodies)+) concentrations; is a key regulator of CRAC channel-mediated SOCE

EF-Hand Calcium Binding Domain 4B (EFCAB4B) Antigen Profile

Protein Summary

Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex (By similarity).

Gene names and symbols associated with EFCAB4B

  • EF-hand calcium binding domain 4B (EFCAB4B) antibody
  • EF-hand calcium binding domain 4B (Efcab4b) antibody
  • CRACR2A antibody
  • Gm462 antibody
  • Gm1073 antibody

Protein level used designations for EFCAB4B

CRAC channel regulator 2A , EF-hand calcium-binding domain-containing protein 4B , calcium release-activated calcium channel regulator 2A

GENE ID SPECIES
84766 Homo sapiens
381812 Mus musculus
Selected quality suppliers for anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) Antibodies
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