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anti-Echinoderm Microtubule Associated Protein Like 4 (EML4) Antibodies

May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity). Additionally we are shipping EML4 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EML4 313861  
EML4 27436 Q9HC35
EML4 78798 Q3UMY5
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Top anti-EML4 Antibodies at antibodies-online.com

Showing 10 out of 29 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to EML4 on formalin-fixed paraffin-embedded human prostate cancer. [antibody concentration 10 ug/ml] Western Blot detection against Immunogen (32.56 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to EML4 on formalin-fixed paraffin-embedded human prostate cancer (antibody concentration 10 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged EML4 is 0.1 ng/ml as a capture antibody. Western Blot detection against Immunogen (32.56 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

EML4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-EML4 Antibodies

  1. Human Monoclonal EML4 Primary Antibody for IHC (p), ELISA - ABIN565390 : Radtke, Rezaie, Kugler, Zabel, Schultz, Vollmer, Goldmann, Lang: Expression analysis of EML4 in normal lung tissue and non-small cell lung cancer (NSCLC) in the absence and presence of chemotherapeutics. in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2010 (PubMed)

More Antibodies against EML4 Interaction Partners

Human Echinoderm Microtubule Associated Protein Like 4 (EML4) interaction partners

  1. Data show that inhibition of echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK (show ALK Antibodies))-mediated stem-like properties enhances the anti-tumor effect.

  2. This review describes the biology of EML4 and ALK (show ALK Antibodies), explains the main features of EML4-ALK (show ALK Antibodies) fusion proteins and outline the therapies that target EML4-ALK (show ALK Antibodies) in cancer. [review]

  3. We further showed that both EML4-ALK (show ALK Antibodies) and mutant forms of EGFR (show EGFR Antibodies) modulate PD-L1 (show CD274 Antibodies) expression via common downstream pathways mediated by MEK (show MAP2K1 Antibodies)-ERK (show EPHB2 Antibodies) and by PI3K (show PIK3CA Antibodies)-AKT (show AKT1 Antibodies).

  4. EGFR (show EGFR Antibodies) gene mutations and the EML4-ALK (show ALK Antibodies) fusion gene were detected in 92 lung adenocarcinoma patients in China.

  5. In the absence of EML4, NUDC was no longer able to localize to the mitotic spindle, whereas NUDC was dispensable for EML4 localization.

  6. It was revealed that the EML4-ALK (show ALK Antibodies) fusion gene was observed predominantly in adenocarcinoma, non-smoking and non-small-cell lung cancers (NSCLC) patients, especially those diagnosed in the advanced clinical stage of NSCLC.

  7. Results suggested that chromothripsis may be a mechanism of oncogenic rearrangement of EML4-ALK (show ALK Antibodies).

  8. The FISH-based method of detecting EML4-ALK (show ALK Antibodies) rearrangement in lung cancer may miss a significant number of patients who could benefit from targeted ALK (show ALK Antibodies) therapy. IHC should be strongly considered, and NGS is recommended in borderline cases.

  9. H1299 NSCLC cells stably expressing EML4-ALK (show ALK Antibodies) acquire epithelial-mesenchymal transition (EMT (show ITK Antibodies)) phenotype, associated with enhanced invasive migration and increased expression of EMT (show ITK Antibodies)-inducing transcription factors.

  10. We have determined crystal structures of the coiled-coils from EML2 (show EML2 Antibodies) and EML4, which describe the structural basis of both EML self-association and oncogenic EML4-ALK (show ALK Antibodies) activation.

EML4 Antigen Profile

Protein Summary

May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity).

Gene names and symbols associated with EML4

  • echinoderm microtubule associated protein like 4 (Eml4) antibody
  • echinoderm microtubule associated protein like 4 (EML4) antibody
  • echinoderm microtubule associated protein like 4 (eml4) antibody
  • 4930443C24Rik antibody
  • AI644019 antibody
  • C2orf2 antibody
  • ELP120 antibody
  • EMAP-4 antibody
  • EMAPL4 antibody
  • EML4 antibody
  • MGC89332 antibody
  • ROPP120 antibody

Protein level used designations for EML4

echinoderm microtubule-associated protein-like 4 , echinoderm microtubule associated protein like 4 , echinoderm microtubule-associated protein-like 4-like , restrictedly overexpressed proliferation-associated protein , ropp 120 , EMAP-4

GENE ID SPECIES
313861 Rattus norvegicus
483048 Canis lupus familiaris
540187 Bos taurus
100515021 Sus scrofa
448764 Xenopus (Silurana) tropicalis
459180 Pan troglodytes
715091 Macaca mulatta
771345 Gallus gallus
100053784 Equus caballus
100453034 Pongo abelii
27436 Homo sapiens
78798 Mus musculus
735022 Xenopus laevis
Selected quality suppliers for anti-EML4 (EML4) Antibodies
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