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The protein encoded by EPDR1 is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. Additionally we are shipping EPDR1 Proteins (8) and many more products for this protein.
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Study results suggest functional involvement of EPDR1 in the etiology of Dupuytren's Disease.
EPDR1 exhibits a pattern of isoform abundance dependent on KRAS G13D and G12D mutations.
Results of this study suggest that EPDR1 gene can be added to a growing list of genes associated with Dupuytren's disease development.
Shows that the mouse ortholog is a lysosomal protein.
A novel density shift method was used to demonstrate that EPDR resides in the lysosome.
The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
ependymin related protein 1 (zebrafish)
, ependymin related protein 1
, mammalian ependymin related protein 1
, mammalian ependymin-related protein 1
, upregulated in colorectal cancer gene 1 protein
, ependymin 2
, ependymin related protein 2
, upregulated in colorectal cancer gene 1