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Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Additionally we are shipping ETV3 Antibodies (16) and many more products for this protein.
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Frequent copy number gains at 1q21 and 1q32 are associated with overexpression of the ETS (show ETS1 Proteins) transcription factors ETV3 and ELF3 (show ELF3 Proteins) in breast cancer irrespective of molecular subtypes.
PE-1/METS is an antiproliferative Ets (show ETS1 Proteins) repressor factor induced by CREB-1 (show CREB1 Proteins)/CREM (show CREM Proteins)-1 during macrophage differentiation
Differential repression of c-myc (show MYC Proteins) and cdc2 (show CDK1 Proteins) gene expression by ERF and PE-1/METS.
The ETV3 expression was strongly induced by the STAT3 (show STAT3 Proteins) pathway regulated by IL-10 (show IL10 Proteins) but not by STAT3 (show STAT3 Proteins) signaling activated by IL-6 (show IL6 Proteins), which cannot activate the anti-inflammatory signaling pathway.
Data show that ETV3 (a member of the E twenty-six family of transcriptional regulators), was extensively phosphorylated on sites within canonical and noncanonical ERK (show EPHB2 Proteins) motifs.
ETS (show ETS1 Proteins) gene expression is an essential requirement for normal sensory neuron differentiation
Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.
ets variant 3
, ETS translocation variant 3
, ets variant gene 3
, ETS domain transcriptional repressor PE1
, ets variant gene 3, ETS family transcriptional repressor
, mitogenic Ets transcriptional suppressor
, SH2 domain containing phosphatase anchor protein 1
, ETS-domain protein
, ETS-domain transcriptional repressor
, mitogenic Ets transcriptional suppressor METS