Eukaryotic Translation Elongation Factor 1 alpha 1 Proteins (EEF1A1)

EEF1A1 encodes a protein which participates in protein translation in mitochondria. Additionally we are shipping eEF1A1 Antibodies (74) and eEF1A1 Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EEF1A1 1915 P68104
EEF1A1 13627 P10126
EEF1A1 171361 P62630
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Top eEF1A1 Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$205.80
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Yeast Toxoplasma gondii His tag   1 mg Log in to see 60 to 71 Days
$3,111.17
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Yeast Cyanophora paradoxa His tag   1 mg Log in to see 60 to 71 Days
$3,135.00
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Yeast Plasmodium falciparum His tag   1 mg Log in to see 60 to 71 Days
$3,138.67
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Yeast Theileria parva His tag   1 mg Log in to see 60 to 71 Days
$3,142.33
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Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
$3,300.00
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Yeast Zebrafish His tag   1 mg Log in to see 60 to 71 Days
$3,300.00
Details

EEF1A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine)

Rat (Rattus)

Top referenced eEF1A1 Proteins

  1. Human eEF1A1 Protein expressed in HEK-293 Cells - ABIN2719940 : Koo, Chae, Kim, Kang, Kim, Kwak, Jung, Cho, Choi, Park, Shin, Jang, Shin, Hwang, Yi, Park: Identification of novel autoantibodies in type 1 diabetic patients using a high-density protein microarray. in Diabetes 2014 (PubMed)
    Show all 2 Pubmed References

  2. Human eEF1A1 Protein expressed in Wheat germ - ABIN1352341 : Fan, Cui, Wei, Liu, Li, He, Ye, Zhu, Wei: eEF1A1 binds and enriches protoporphyrin IX in cancer cells in 5-aminolevulinic acid based photodynamic therapy. in Scientific reports 2016 (PubMed)

More Proteins for Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) Interaction Partners

Rabbit Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) interaction partners

  1. Data (including data from studies using purified proteins/hepatocyte lysates) suggest eEF1A1/Sgt1a interact as multimer; D2/D3 domains of eEF1A1 and TPR domain of Sgt1 (show SUGT1 Proteins) are involved in multimer formation; Sgt1 (show SUGT1 Proteins) competes with viral RNA to bind to eEF1A.

  2. The A,A( *),A' helices region did not interact with actin; however, its removal eliminates the actin bundling activity of eEF1A, probably due to the destruction of a dimeric structure of eEF1A.

Human Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) interaction partners

  1. The present study identifies METTL21B (show METTL21B Proteins) as the enzyme responsible for methylation of eEF1A on Lys (show LYZ Proteins)-165 and shows that this modification is dynamic, inducible and likely of regulatory importance.

  2. we identify a novel signaling hub centering on the NLRX1 TUFM (show Tufm Proteins) protein complex, promoting autophagic flux. Defects in the expression of either NLRX1 or TUFM (show Tufm Proteins) result in compromised autophagy when treated with EGFR (show EGFR Proteins) inhibitors.These findings expand our understanding of the components involved in head and neck squamous cell carcinoma autophagy machinery that responds to EGFR (show EGFR Proteins) inhibitors.

  3. EEF1A1 is somatically mutated in 9% of follicular lymphoma tumors.

  4. we show how FAT10 (show UBD Proteins) stabilizes the translation elongation factor (show TSFM Proteins) eEF1A1, which contributes to cancer cell proliferation

  5. The expression of RPL13A (show RPL13A Proteins) and EEF1A1 was not affected by differentiation, thus being these genes the most stable candidates as reference genes for RT-PCR.

  6. Study demonstrated that PAK4 (show PAK4 Proteins) interacted with eEF1A1 to promote migration and invasion of gastric cancer cells, thereby providing new insights into the function of PAK4 (show PAK4 Proteins) and eEF1A1 in the progression of gastric cancer.

  7. this study demonstrates that eEF1A1 regulates the subcellular location of expanded poly(A) proteins and is therefore a potential therapeutic target for combating the pathogenesis of poly(A) diseases.

  8. analysis of eEF1A1 oligomerization reveals that specific cysteine residues are required for this oligomerization activity

  9. Data (including data from studies using purified proteins/hepatocyte lysates) suggest eEF1A1/Sgt1a interact as multimer; D2/D3 domains of eEF1A1 and TPR domain of Sgt1 (show SUGT1 Proteins) are involved in multimer formation; Sgt1 (show SUGT1 Proteins) competes with viral RNA to bind to eEF1A.

  10. Data indicate that the methylation of lysine (Lys (show LYZ Proteins)) in elongation factor 1A (eEF1A) by methyltransferase is conserved from yeast to human.

Pig (Porcine) Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) interaction partners

  1. Genomic organization, polymorphism, chromosomal assignment and spatial and temporal expressions of EEF1A1 gene was presented.

  2. Collectively, these results suggest that eEF1A interacts with viral NS5A and negatively regulates the growth of classical swine fever virus.

  3. Promoter analysis revealed porcine TEF1 was regulated, in a TATA-independent manner, by a specific intact initiator element, and numerous binding motifs of multiple transcription factors, including SP1, CREB/ATF and AREB6.

Mouse (Murine) Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) interaction partners

  1. Hepatic eEF1A-1 was increased in ob/ob mice maintained on AIN-76A diet. Liver eEF1A-1 is induced during severe hepatic steatosis and the onset of hepatic ER stress.

  2. Data show that translation elongation factor (show TSFM Proteins) eEF1A1 coordinates the heat shock response by adjusting transcriptional yield to translational needs.

  3. Identified are several GBX2 (show GBX2 Proteins) candidate target genes including ROBO1 (show ROBO1 Proteins), PLXNA4 (show PLXNA4 Proteins), SLIT3 (show SLIT3 Proteins), NRP1 (show NRP1 Proteins), PCDH15 (show PCDH15 Proteins), USH2A, NOTCH2 (show NOTCH2 Proteins), and EEF1A1 that are likely to contribute many of the developmental defects observed in Gbx2 (show GBX2 Proteins) mutant organisms.

  4. Under some stressful stimulations IFIT1 (show IFIT1 Proteins) may participate in cell death pathways by interaction with eEF1A (show EEF1A2 Proteins).

  5. both eEF1A (show EEF1A2 Proteins) and MYPT1 (show PPP1R12A Proteins) have roles in EGCG signaling for cancer prevention through 67LR (show RPSA Proteins)

  6. The cell death was associated with downregulation of eukaryotic translation elongation factor-1 alpha 1 (eEF1A1/EF-1alpha) expression in conjunction with accumulation of its mRNA in processing bodies (P bodies).

eEF1A1 (EEF1A1) Protein Profile

Protein Summary

This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17.

Gene names and symbols associated with EEF1A1

  • eukaryotic translation elongation factor 1 alpha 1 (EEF1A1)
  • eukaryotic translation elongation factor 1 alpha 1b (eef1a1b)
  • eukaryotic translation elongation factor 1 alpha 1 (LOC100358931)
  • elongation factor 1-alpha (tufA)
  • eukaryotic translation elongation factor 1 alpha 1 (Eef1a1)
  • eukaryotic translation elongation factor 1 alpha 1 (eef1a1)
  • eukaryotic translation elongation factor 1 alpha 1, like 1 (eef1a1l1)
  • Tu translation elongation factor, mitochondrial (TUFM)
  • CCS-3 protein
  • CCS3 protein
  • chunp6927 protein
  • COXPD4 protein
  • EE1A1 protein
  • EEF-1 protein
  • eef1a protein
  • eEF1A-1 protein
  • eef1a-s protein
  • EEF1A1 protein
  • Eef1a2 protein
  • Eef1a2l1 protein
  • eef1as protein
  • EF-1-ALPHA-S protein
  • EF-1A protein
  • EF-Tu protein
  • EF-TuMT protein
  • ef1a protein
  • EF1A1 protein
  • EFL1-alpha protein
  • EFTU protein
  • GRAF-1EF protein
  • HNGC:16303 protein
  • ik:tdsubc_2a3 protein
  • ik:tdsubc_2b3 protein
  • LENG7 protein
  • P43 protein
  • PTI1 protein
  • RABEFLA2 protein
  • SI protein
  • tdsubc_2a3 protein
  • wu:fa91c07 protein
  • wu:fa94b03 protein
  • wu:fi13b09 protein
  • wu:fj34g08 protein
  • xx:tdsubc_2a3 protein
  • xx:tdsubc_2b3 protein
  • zgc:110335 protein

Protein level used designations for EEF1A1

elongation factor 1-alpha 1 , eukaryotic translation elongation factor 1 alpha 1 , elongation factor 1 alpha , elongation factor Tu , EF-1-alpha-1 , EF-Tu , CTCL tumor antigen , EF1a-like protein , cervical cancer suppressor 3 , elongation factor 1 alpha subunit , eukaryotic elongation factor 1 A-1 , eukaryotic translation elongation factor 1 alpha 1-like 14 , glucocorticoid receptor AF-1 specific elongation factor , leukocyte receptor cluster (LRC) member 7 , leukocyte receptor cluster member 7 , prostate tumor-inducing protein 1 , translation elongation factor 1 alpha 1-like 14 , eukaryotic translation elongation factor 1 alpha 2 , eEF1A-1 , elongation factor 1 A-1 , EF-1 alpha2 , eukaryotic translation elongation factor 1 alpha 2 like 1 , Elongation factor 1-alpha 1-like protein , elongation factor 1a , Elongation factor Tu , Eukaryotic elongation factor 1 A-1 , elongation factor EF-1 alpha , EF-1 alpha , elongation factor 1-alpha, somatic form , elongation factor-1 alpha , eukaryotic translation elongation factor 1 alpha, somatic form , EF-1-alpha , ef-1 alpha , elongation factor 1-alpha , elongation factor Tu, mitochondrial

GENE ID SPECIES
716010 Macaca mulatta
100004503 Danio rerio
100303511 Saccoglossus kowalevskii
100358931 Oryctolagus cuniculus
801571 Cyanophora paradoxa
373963 Gallus gallus
1915 Homo sapiens
403506 Canis lupus familiaris
574059 Sus scrofa
13627 Mus musculus
171361 Rattus norvegicus
282220 Bos taurus
493922 Felis catus
100009682 Equus caballus
100009189 Oryctolagus cuniculus
100689276 Cricetulus griseus
386604 Xenopus laevis
30516 Danio rerio
7284 Homo sapiens
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