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anti-Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) Antibodies

EIF2B1 encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Additionally we are shipping Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EIF2B1 209354 Q99LC8
EIF2B1 64514 Q64270
EIF2B1 1967 Q14232
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Top anti-Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-EIF2B1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate WB Suggested Anti-EIF2B1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Jurkat cell lysate  EIF2B1 is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB EIF2B1 Antibody (Center)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the EIF2B1 antibody detected the EIF2B1 protein (arrow). EIF2B1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF2B1 Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB EIF2B1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF2B1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. EIF2B1 Antibody (Center) western blot analysis in 293 cell line lysates (35µg/lane).This demonstrates the EIF2B1 antibody detected the EIF2B1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated FACS, IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit PE FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IF, ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details

EIF2B1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


Rat (Rattus) ,


Human ,
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Top referenced anti-Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Antibodies

  1. Human Polyclonal EIF2B1 Primary Antibody for EIA, IHC (p) - ABIN952043 : Hiyama, Ito, Imataka, Yokoyama: Crystal structure of the alpha subunit of human translation initiation factor 2B. in Journal of molecular biology 2009 (PubMed)
    Show all 3 references for ABIN952043

  2. Cow (Bovine) Polyclonal EIF2B1 Primary Antibody for WB - ABIN2784713 : Maletkovic, Schiffmann, Gorospe, Gordon, Mintz, Hoffman, Alper, Lynch, Singhal, Harding, Amartino, Brown, Chan, Renaud, Geraghty, Jensen, Senbil, Kadom, Nazarian, Yuanjian Feng, Zuyi Wang, Hartka, Morizono, Vanderver: Genetic and clinical heterogeneity in eIF2B-related disorder. in Journal of child neurology 2008 (PubMed)

More Antibodies against Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Interaction Partners

Mouse (Murine) Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) interaction partners

  1. These are the first data that mechanistically link eIF2Bepsilon (show EIF2B5 Antibodies) abundance to skeletal myofibre hypertrophy.

  2. A point mutation in translation initiation factor eIF2B (show EIF2B4 Antibodies) leads to Vanishing White Matter disease.

  3. Inhibition of pancreatic protein synthesis in this model of acute pancreatitis most likely results from inhibition of translation initiation from increased eIF2alpha (show EIF2A Antibodies) phosphorylation, reduction of eIF2B (show EIF2B4 Antibodies) activity, and inhibition of eIF4F (show EIF4A2 Antibodies) complex formation.

Human Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) interaction partners

  1. Oligodendrocytes with truncated or deletion mutants eIF2B showed less tolerable to endoplasmic reticulum stress

  2. These data emphasize the importance of eIF2Balpha in mediating the eIF2 (show EIF2S1 Antibodies) kinase translation-inhibitory activity and may provide insight into the complex nature of vesiculovirus oncolysis.

  3. mutational analysis of the eIF2B genes of patients with an antenatal- or early-infantile-onset encephalopathy and an early demise

  4. Biochemical analyses indicate that mutations analyzed in eIF2Balpha and -epsilon reduce the steady-state level of the affected subunit, while the most severe mutant tested, eIF2Bbeta(V341D), forms complexes with reduced stability and lower eIF2B activity.

  5. analysis of novel mutations in patients with eIF2B-related disorders

  6. Study reports 9 novel mutations in EIF2B genes in 8 patients, increasing number of known mutations to more than 120. Using homology modeling, analyzed the impact of novel mutations on the 5 subunits of eIF2B protein (alpha, beta, gamma, delta, epsilon)

  7. The authors suspected VWM and sequenced the genes EIF2B1-5, which revealed one heterozygous mutation in EIF2B4 (show EIF2B4 Antibodies).

  8. Crystal structure of the alpha subunit of human translation initiation factor 2B.

Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) Antigen Profile

Protein Summary

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

Gene names and symbols associated with EIF2B1

  • translation initiation factor eIF-2B alpha subunit (eIF2b1) antibody
  • translation initiation factor eIF-2B subunit alpha (PGTG_05021) antibody
  • Translation initiation factor eIF-2B subunit alpha (ei2ba) antibody
  • translation initiation factor eif-2b subunit alpha (ei2ba) antibody
  • eukaryotic translation initiation factor 2B, subunit 1 (alpha) (Eif2b1) antibody
  • eukaryotic translation initiation factor 2B, subunit 1 alpha (Eif2b1) antibody
  • eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa (EIF2B1) antibody
  • 26kDa antibody
  • D5Ertd406e antibody
  • DDBDRAFT_0219393 antibody
  • DDBDRAFT_0231375 antibody
  • DDB_0219393 antibody
  • DDB_0231375 antibody
  • eIF-2a antibody
  • EIF2B antibody
  • EIF2BA antibody

Protein level used designations for EIF2B1

translation initiation factor eIF-2B subunit alpha , Translation initiation factor eIF-2B subunit alpha , translation initiation factor eif-2b subunit alpha , eIF-2B GDP-GTP exchange factor subunit alpha , eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kDa) , GTP-exchange protein , eIF-2Balpha

GENE ID SPECIES
8626881 Dictyostelium discoideum AX4
10530886 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100305173 Oncorhynchus mykiss
100528837 Ictalurus punctatus
209354 Mus musculus
64514 Rattus norvegicus
1967 Homo sapiens
516670 Bos taurus
100172592 Pongo abelii
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