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Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. Additionally we are shipping EIF3A Kits (6) and EIF3A Proteins (3) and many more products for this protein.
Showing 10 out of 72 products:
Human Polyclonal EIF3A Primary Antibody for EIA, WB - ABIN952046
Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. in Genomics 2007
Show all 4 references for ABIN952046
Human Polyclonal EIF3A Primary Antibody for ICC, IF - ABIN438727
Chazal, Daguenet, Wendling, Ulryck, Tomasetto, Sargueil, Le Hir: EJC core component MLN51 interacts with eIF3 and activates translation. in Proceedings of the National Academy of Sciences of the United States of America 2013
Show all 3 references for ABIN438727
Human Polyclonal EIF3A Primary Antibody for IHC (p), WB - ABIN656879
Enchev, Schreiber, Beuron, Morris: Structural insights into the COP9 signalosome and its common architecture with the 26S proteasome lid and eIF3. in Structure (London, England : 1993) 2010
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Human Polyclonal EIF3A Primary Antibody for ELISA, WB - ABIN563740
Kroczynska, Kaur, Katsoulidis, Majchrzak-Kita, Sassano, Kozma, Fish, Platanias: Interferon-dependent engagement of eukaryotic initiation factor 4B via S6 kinase (S6K)- and ribosomal protein S6K-mediated signals. in Molecular and cellular biology 2009
eIF3a (show EIF6 Antibodies) may function as a novel regulator to modulate hepatic stellate cell activation, potentially through inhibiting the TGF-beta1 (show TGFB1 Antibodies)/Smad3 (show SMAD3 Antibodies) signaling pathway.
Collybistin (show Arhgef9 Antibodies) forms a complex with mTOR (show FRAP1 Antibodies) and eIF3 and by sequestering these proteins downregulates mTORC1 signaling and protein synthesis potentially contributing to intellectual disability and autism.
eIF3 has a role in controlling cell size independently of S6K1 (show RPS6KB1 Antibodies)-activity
eIF3a (show EIF6 Antibodies) improves ovarian cancer patients' response to cisplatin-based chemotherapy by down regulating XPC (show XPC Antibodies) and p27(Kip1 (show CDKN1B Antibodies)).
eIF3a (show EIF6 Antibodies) SNPs are significantly correlated with platinum-based chemotherapy toxicities in Chinese non-small cell lung carcinoma patients.
Data conclude that eIF3a (show EIF6 Antibodies) expression may have a profound effect on the urinary bladder cancer phenotype and, in addition, may serve as a prognostic marker for low grade UBCs.
Taken together, these results show that Neurospora crassa eIF3 provides a tractable system for probing the structure and function of human-like eIF3 in the context of living cells.
Of the total, the deregulation of several genes (CDK1 (show CDK1 Antibodies), CDK2 (show CDK2 Antibodies), CDK4 (show CDK4 Antibodies), MCM2 (show MCM2 Antibodies), MCM3 (show MCM3 Antibodies), MCM4 (show MCM4 Antibodies), EIF3a (show EIF6 Antibodies) and RPN2 (show PSMD1 Antibodies)) were potentially associated with disease development and progression.
At 37 degrees C, P185(HER2 (show ERBB2 Antibodies)) internalized through coated pits and vesicles and concentrated in the endosomes and multivesicular bodies in the cells of both cell lines, as well as in lysosomes in cells BT-474
findings suggested altered eIF3a (show EIF6 Antibodies) expression closely correlated with p27 (show PAK2 Antibodies) status, and the association was of prognostic value for resected NSCLC
The pleiotropic mouse phenotype extra-toes spotting (show EIF3C Antibodies) is caused by translation initiation factor Eif3c (show EIF3C Antibodies) mutations.
May play some roles in development and differentiation; decreased eIF3a expression may be a pre-requisite of intestinal epithelial cell differentiation.
Stable expression of a truncated eIF3e (show EIF3E Antibodies) in NIH 3T3 cells causes malignant transformation
eIF3a expression oscillated with cell cycle and peaked in S phase. Reducing eIF3a expression also reduced cell proliferation rate by elongating cell cycle but did not change the cell cycle distribution.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa
, eukaryotic translation initiation factor 6
, Eukaryotic translation initiation factor 3 subunit 10
, eukaryotic translation initiation factor 3 subunit 10
, eukaryotic translation initiation factor 3 subunit A
, EIF3, p180 subunit
, centrosomin homolog
, cytoplasmic protein p167
, eIF3 p167
, eIF3 p180
, eIF3 p185
, eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD)
, eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD)
, eukaryotic translation initiation factor 3, subunit 10, 170kD
, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN)
, eukaryotic translation initiation factor 3, subunit 10 (theta)