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anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) Antibodies

EYA2 encodes a member of the eyes absent (EYA) family of proteins. Additionally we are shipping EYA2 Proteins (6) and EYA2 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EYA2 14049 O08575
EYA2 2139 O00167
EYA2 156826  
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Top anti-EYA2 Antibodies at antibodies-online.com

Showing 10 out of 76 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB EYA2 Antibody (Center)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EYA2 antibody detected the EYA2 protein (arrow). Western blot analysis of EYA2 (arrow) using rabbit polyclonal EYA2 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the EYA2 gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to EYA2 on HeLa cell (antibody concentration 10 µg/mL). Western Blot analysis of EYA2 expression in transfected 293T cell line by EYA2 monoclonal antibody (M04), clone 2F8. Lane 1: EYA2 transfected lysate(59.2 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Rat Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated WB Western Blot analysis of EYA2 expression in transfected 293T cell line by EYA2 MaxPab polyclonal antibody.Lane 1: EYA2 transfected lysate(59.18 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to EYA2 on HeLa cell. [antibody concentration 10 ug/ml] EYA2 monoclonal antibody (M04), clone 2F8 Western Blot analysis of EYA2 expression in IMR-32 . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB Western Blot showing Eya2 antibody used at a concentration of 1.0 ug/ml against Rat Muscle Lysate 50 μg Log in to see 7 to 9 Days
$473.93
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

EYA2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against EYA2 Interaction Partners

Mouse (Murine) Eyes Absent Homolog 2 (Drosophila) (EYA2) interaction partners

  1. Eya2 in a physical complex with Six1 (show SIX1 Antibodies) plays a critical role in physiological hypertrophy.

  2. Eya2 protein is required for hypaxial somitic myogenesis in the mouse embryo

  3. Eya2 prevents adverse cardiac remodeling under pressure overload partly through altering metabolic gene expression and preserving PI3K/Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway.

Human Eyes Absent Homolog 2 (Drosophila) (EYA2) interaction partners

  1. SIX1 (show SIX1 Antibodies) and EYA are often co-overexpressed in tumors, and the SIX1 (show SIX1 Antibodies)-EYA2 interaction has been shown to be critical for metastasis in a breast cancer model.

  2. Decreased expression of EYA2 is associated with pancreatic adenocarcinomas.

  3. This interaction suggests that CDK6 (show CDK6 Antibodies) regulates EYA2 activity, a mechanism that could be important in development and in cancer.

  4. MIR30A represses Eya2 expression by binding to the 3'-untranslated region of Eya2.The MIR30A/EYA2 axis regulates breast cancer cell proliferation and migration.

  5. Functional roles of candidate genes EYA2 (20q13) and hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-375 (2q35) were studied by siRNA-mediated knock-down and overexpression, respectively, in hrHPV-containing cell lines.

  6. Given that SIX1 (show SIX1 Antibodies) and EYA are overexpressed in many tumor types, our data indicate that targeting the SIX1 (show SIX1 Antibodies)-EYA complex may be a potent approach to inhibit tumor progression in multiple cancer types

  7. Studies indicate that the RNA and protein levels of Eya2 is upregulated in ovarian cancer.

  8. Data implicate Eya2 as a necessary co-factor for many of the metastasis promoting functions of Six1 (show SIX1 Antibodies).

  9. Expression of EYA2 in lung adenocarcinoma is augmented.

  10. Based on observation that the dachshund-binding site is located between the catalytic core & Sine Oculis binding sites within ED-Eya2, we propose that catalytic activity can be translated to SO binding through DAC (show AADAC Antibodies), which acts as a transcriptional switch.

EYA2 Antigen Profile

Protein Summary

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may be post-translationally modified and may play a role in eye development. A similar protein in mice can act as a transcriptional activator. Alternative splicing results in multiple transcript variants, but the full-length natures of all of these variants have not yet been determined.

Gene names and symbols associated with EYA2

  • eyes absent homolog 2 (Drosophila) (EYA2) antibody
  • eyes absent homolog 2 (Drosophila) (eya2) antibody
  • eyes absent homolog 2 (eya2) antibody
  • eyes absent homolog 2 (LOC100218165) antibody
  • eyes absent 2 homolog (Drosophila) (Eya2) antibody
  • eyes absent homolog 2 (Drosophila) (Eya2) antibody
  • EAB1 antibody
  • EYA2 antibody
  • zgc:92279 antibody

Protein level used designations for EYA2

eyes absent 2 , eyes absent homolog 2 , eyes absent homolog 2 (Drosophila) , Drosophila-type eyes absent 2-like protein , eyes absent 2 homolog

GENE ID SPECIES
395745 Gallus gallus
100071250 Equus caballus
458305 Pan troglodytes
447819 Danio rerio
100037919 Xenopus (Silurana) tropicalis
100218165 Taeniopygia guttata
14049 Mus musculus
2139 Homo sapiens
156826 Rattus norvegicus
615264 Bos taurus
609926 Canis lupus familiaris
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