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Stimulates the proliferation of early hematopoietic cells by activating FLT3. Additionally we are shipping FMS-Like tyrosine Kinase 3 Ligand Kits (28) and FMS-Like tyrosine Kinase 3 Ligand Proteins (3) and many more products for this protein.
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Bone marrow-derived CD117+ hematopoietic progenitor cells differentiate into thymic dendritic cells in the fetal thymus organ culture system in the presence of Flt3L (show FLT3LG Antibodies).
Flt3L (show FLT3LG Antibodies) significantly contributes to innate lymphoid cells and Peyer's patches development by targeting lymphoid progenitor cells during fetal and adult life.
unlike G-CSF (show CSF3 Antibodies), Flt3 (show FLT3 Antibodies)-L had an indirect effect on EI macrophages, as it was not detected at the surface of EI macrophages or erythroid progenitors.
Study showed shown Flt3L (show FLT3LG Antibodies)-dependent accumulation of a population of DNGR-1(CLEC9A (show CLEC9A Antibodies))-EGFP+ CD45h CD11blow MHCII+ myeloid cells in the brain
Data indicate that Flt3 ligand (show FLT3LG Antibodies) knockout (Flt3L (show FLT3LG Antibodies)-/-) mice are unable to control infection with Toxoplasma gondii.
inhibition of the calcineurin (show PPP3CA Antibodies)-nuclear factor of activated T cells pathway enhances the proliferation of granulocyte-monocyte progenitors both in vitro and in vivo
The Cx3cr1 (show CX3CR1 Antibodies)(gfp/+)Flt3L (show FLT3LG Antibodies)(-/-) reporter mouse model represents a powerful tool to visualize monocyte activities in bone marrow.
Flt3L (show FLT3LG Antibodies)(-/-) mice showed a marked decrease in clinical arthritis scores and incidence of arthritis in both acute and chronic phases of CIA (show NCOA5 Antibodies) compared with WT mice. Moreover, decreased synovial inflammation and joint destruction was observed.
Flt3L (show FLT3LG Antibodies) enhances global T cell and humoral immunity as well as both the numbers and antigen capture capacity of migratory dendritic cells and classical lymphoid-resident dendritic cells
Here, we build on the observation that Langerin (show CD207 Antibodies)-CD11b (show ITGAM Antibodies)- migrating dendritic cells are Flt3L (show FLT3LG Antibodies) dependent and strongly Flt3L (show FLT3LG Antibodies) responsive, which may relate them to classical dendritic cells.
Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
, fms-related tyrosine kinase 3 ligand
, fms-like tyrosine kinase 3 ligand