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FYCO1 encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. Additionally we are shipping FYCO1 Proteins (4) and FYCO1 Kits (2) and many more products for this protein.
Showing 10 out of 29 products:
Human Polyclonal FYCO1 Primary Antibody for ELISA, WB - ABIN566354
Pankiv, Alemu, Brech, Bruun, Lamark, Overvatn, Bjørkøy, Johansen: FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport. in The Journal of cell biology 2010
FYCO1 requires a functional LC3A (show MAP1LC3A Antibodies)/B-preferring LC3 (show MAP1LC3A Antibodies)-interacting Region (LIR (show CD300C Antibodies)) motif to facilitate efficient maturation of autophagosomes under basal conditions, whereas starvation-induced autophagy was unaffected
FYCO1 is involved in lens development and transparency in humans, and mutations in this gene are one of the most common causes of autosomal-recessive congenital cataracts in the Pakistani population.
We have characterized the LC3 (show MAP1LC3A Antibodies)-, Rab7 (show RAB7B Antibodies)-, and phosphatidylinositol-3-phosphate-binding domains in FYCO1 and mapped part of the CC region essential for MT plus end-directed transport.
FYVE and coiled-coil domain containing 1 (FYCO1), a protein previously implicated in autophagosome trafficking, is recruited directly by LC3 (show MAP1LC3A Antibodies) to Dectin-1 (show CLEC7A Antibodies) phagosomes.
This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2).
FYVE and coiled-coil domain-containing protein 1
, FYVE and coiled-coil domain containing 1
, FYVE and coiled-coil domain-containing protein 1-like
, RUN and FYVE domain containing 3
, zinc finger FYVE domain-containing protein 7
, maternal embryonic message 2