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anti-Fascin Homolog 1, Actin Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) Antibodies

Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio.

list all antibodies Gene Name GeneID UniProt
FSCN1 14086 Q61553
FSCN1    
FSCN1    
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Top anti-Fascin Homolog 1, Actin Bundling Protein (Strongylocentrotus Purpuratus) Antibodies at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brainstem with Anti-Fascin1 Polyclonal Antibody, Unconjugated (ABIN728293) at 1:300, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human gastric carcinoma with Anti-Fascin1 Polyclonal Antibody, Unconjugated (ABIN728293) at 1:300, followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, PE conjugated used at 1:200 dilution for 40 minutes at 37°C. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$175.80
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Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$429.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 6 to 8 Days
$431.20
Details

FSCN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human


Rat (Rattus)


More Antibodies against Fascin Homolog 1, Actin Bundling Protein (Strongylocentrotus Purpuratus) Interaction Partners

Mouse (Murine) Fascin Homolog 1, Actin Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. Fascin1 facilitates phagolysosomal fusion for killing of phagocytosed Listeria. It binds to LC3 (show MAP1LC3A Antibodies), an autophagosome marker, both in vivo & in vitro. It plays a critical role in dendritic cell survivalduring Listeria infection.

  2. A tightly regulated phospho/dephospho-fascin cycle modulated by extracellular signals is required for the polarized morphology and migration in neuroblasts, thus contributing to efficient neurogenesis.

  3. fascin 1 promotes cell migration and has a role in growth and cell cycle progression

  4. Suppression of fascin expression results in reduction of activation-induced migration and invasion in mouse monocytic leukemia (show KAT6B Antibodies) RAW264.7 macrophages.

  5. Both STAT3 (show STAT3 Antibodies) and NFkappaB are required for the cytokine-induced expression of fascin in cancer cells.

  6. fascin-1 is principally expressed in neural and mesenchymal derivatives during embryonic development

  7. We propose that fascin is a key specific actin cross-linker, providing stiffness for filopodial bundles, and that its dynamic behavior allows for efficient coordination between elongation and bundling of filopodial actin filaments.

  8. Fascin is a novel target of beta-catenin (show CTNNB1 Antibodies)-TCF (show HNF4A Antibodies) signaling and is expressed at the invasive front of human colon cancer

  9. Fascin mRNA & protein levels were significantly lower in the cultured ANXA2 (show ANXA2 Antibodies)(-/-) cells than in cultured ANXA2 (show ANXA2 Antibodies)(+/+) cells. ANXA2 (show ANXA2 Antibodies) may be an inducer or enhancer of fascin expression at the transcription level.

  10. study found that Rab35 (show RAB35 Antibodies) regulates the assembly of actin filaments in filopodia formation; effect was mediated by the actin-bundling protein fascin, which directly associated with active Rab35 (show RAB35 Antibodies)

Fascin Homolog 1, Actin Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) Antigen Profile

Protein Summary

Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration (By similarity).

Gene names and symbols associated with FSCN1

  • fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) (Fscn1) antibody
  • AI663989 antibody
  • Fan1 antibody
  • fascin-1 antibody

Protein level used designations for FSCN1

fascin , fascin 1 , singed-like protein

GENE ID SPECIES
14086 Mus musculus
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