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anti-Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) Antibodies

FSCN1 encodes a member of the fascin family of actin-binding proteins. Additionally we are shipping Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) Kits (32) and Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) Proteins (18) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FSCN1 14086 Q61553
FSCN1 683788 P85845
FSCN1 6624 Q16658
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Top anti-Fascin Homolog 1, Actin Bundling Protein (Strongylocentrotus Purpuratus) Antibodies at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brainstem with Anti-Fascin1 Polyclonal Antibody, Unconjugated (ABIN728293) at 1:300, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human gastric carcinoma with Anti-Fascin1 Polyclonal Antibody, Unconjugated (ABIN728293) at 1:300, followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, PE conjugated used at 1:200 dilution for 40 minutes at 37°C. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$429.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 6 to 8 Days
$431.20
Details

FSCN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) Antibodies

  1. Mouse (Murine) Polyclonal FSCN1 Primary Antibody for WB - ABIN610551 : Attramadal, Arriza, Aoki, Dawson, Codina, Kwatra, Snyder, Caron, Lefkowitz: Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family. in The Journal of biological chemistry 1992 (PubMed)
    Show all 3 references for ABIN610551

  2. Human Polyclonal FSCN1 Primary Antibody for EIA, WB - ABIN452989 : Qualtrough, Singh, Banu, Paraskeva, Pignatelli: The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro. in British journal of cancer 2009 (PubMed)
    Show all 2 references for ABIN452989

  3. Dog (Canine) Polyclonal FSCN1 Primary Antibody for IF (p), IHC (p) - ABIN673011 : Majchrzak, Lo Re, Gajewska, Bulkowska, Homa, Paw?owski, Motyl, Murphy, Król: Migrastatin analogues inhibit canine mammary cancer cell migration and invasion. in PLoS ONE 2013 (PubMed)
    Show all 2 references for ABIN673011

  4. Human Polyclonal FSCN1 Primary Antibody for FACS, IHC (p) - ABIN390697 : Ono, Yamakita, Yamashiro, Matsudaira, Gnarra, Obinata, Matsumura: Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin. in The Journal of biological chemistry 1997 (PubMed)
    Show all 2 references for ABIN390697

More Antibodies against Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) Interaction Partners

Fruit Fly (Drosophila melanogaster) Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. Alterations in nuclear Fascin levels result in defects in nucleolar morphology in both Drosophila follicles and cultured mammalian cells, suggesting that nuclear Fascin plays an important role in nucleolar architecture.

  2. essential for actin bundle initiation and stiffening during embryonic tracheal system development

  3. Fascin and Ena cooperate to extend and maintain robust filopodia of uniform thickness with aligned barbed ends by a unique mechanistic cycle.

  4. Fascin links Btl/FGFR signalling to the actin cytoskeleton during Drosophila tracheal morphogenesis.

  5. These data lead to the conclusion that prostaglandins regulate Fascin to control actin remodeling

  6. The terminal branchlets of different classes of neurons have distinctive dynamics and are formed on the basis of molecularly separable mechanisms; in particular, class III neurons require fascin for terminal branching whereas class IV neurons do not.

  7. The regulatory role of FascinS52 appears to be tissuespecific, and its importance might depend on the dynamics and the turnover rate of actin bundles between various cell types.

  8. Fascin deficiency does not impair 20-hydroxyecdysone response, but neurites fail to maintain their normal, nearly straight trajectory, instead forming curls and hooks. This is accompanied by abnormally distributed filamentous actin.

  9. Fascin is required for plasmatocyte migration, both as these cells undergo developmental dispersal and during an inflammatory response to epithelial wounding.

  10. study found that Rab35 (show RAB35 Antibodies) regulates the assembly of actin (show ACTB Antibodies) filaments during bristle development; effect was mediated by the a (show ACTB Antibodies)ctin-bundling protein fascin, which directly associated with active R (show RAB35 Antibodies)ab35

Zebrafish Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. These data show that fscn1a-dependent filopodia are required in a subset of NC cells to promote cell migration and NC derivative formation

Mouse (Murine) Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. Fascin1 facilitates phagolysosomal fusion for killing of phagocytosed Listeria. It binds to LC3 (show MAP1LC3A Antibodies), an autophagosome marker, both in vivo & in vitro. It plays a critical role in dendritic cell survivalduring Listeria infection.

  2. A tightly regulated phospho/dephospho-fascin cycle modulated by extracellular signals is required for the polarized morphology and migration in neuroblasts, thus contributing to efficient neurogenesis.

  3. fascin 1 promotes cell migration and has a role in growth and cell cycle progression

  4. Suppression of fascin expression results in reduction of activation-induced migration and invasion in mouse monocytic leukemia (show KAT6B Antibodies) RAW264.7 macrophages.

  5. Both STAT3 (show STAT3 Antibodies) and NFkappaB are required for the cytokine-induced expression of fascin in cancer cells.

  6. fascin-1 is principally expressed in neural and mesenchymal derivatives during embryonic development

  7. We propose that fascin is a key specific actin cross-linker, providing stiffness for filopodial bundles, and that its dynamic behavior allows for efficient coordination between elongation and bundling of filopodial actin filaments.

  8. Fascin is a novel target of beta-catenin (show CTNNB1 Antibodies)-TCF (show HNF4A Antibodies) signaling and is expressed at the invasive front of human colon cancer

  9. Fascin mRNA & protein levels were significantly lower in the cultured ANXA2 (show ANXA2 Antibodies)(-/-) cells than in cultured ANXA2 (show ANXA2 Antibodies)(+/+) cells. ANXA2 (show ANXA2 Antibodies) may be an inducer or enhancer of fascin expression at the transcription level.

  10. study found that Rab35 (show RAB35 Antibodies) regulates the assembly of actin filaments in filopodia formation; effect was mediated by the actin-bundling protein fascin, which directly associated with active Rab35 (show RAB35 Antibodies)

Human Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. Study demonstrates that FSCN1 is associated with increased risk of recurrence in pituitary adenomas and invasion, partially through modifying the expression of Notch (show NOTCH1 Antibodies)/DLL pathway.

  2. The present study revealed an antioncogenic role of miR145 in gastric carcinoma via inhibition of FSCN1, and suggested that miR145 may be used for the treatment of gastric carcinoma.

  3. miR (show MLXIP Antibodies)-145 negatively regulates the protein expression of its target FSCN1 in the NSCLC cell line H129.

  4. MiR (show MLXIP Antibodies)-24 functions as a tumor suppressor in nasopharyngeal carcinoma through targeting FSCN1

  5. Strong fascin-1 expression was found in 14.3% of borderline epithelial tumors of the ovary and linked to features related to elevated risk of recurrence.

  6. FSCN1 plays an important role in non-small cell lung cancer progression and prognosis.

  7. Alterations in nuclear Fascin levels result in defects in nucleolar morphology in both Drosophila follicles and cultured mammalian cells, suggesting that nuclear Fascin plays an important role in nucleolar architecture.

  8. miR (show MLXIP Antibodies)-145 regulates cell migration and invasion in gastric cancer primarily by directly targeting FSCN1.

  9. regulates translation through miR (show MLXIP Antibodies)-155 and miR (show MLXIP Antibodies)-125b, which target 3' UTR (show UTS2R Antibodies) in TNF-alpha (show TNF Antibodies) mRNA

  10. the anti-oncogenic activity of miR (show MLXIP Antibodies)-133a may involve the inhibition of the target gene FSCN1. The present study suggested that miR (show MLXIP Antibodies)-133a may be a potential therapeutic target in the treatment of gastric cancer.

Pig (Porcine) Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. FSCN1 gene plays an in prenatal skeletal muscle development and was a candidate gene for meat production trait.

Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) Antigen Profile

Protein Summary

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Gene names and symbols associated with FSCN1

  • singed (sn) antibody
  • fascin homolog 1, actin-bundling protein (fscn1) antibody
  • fascin homolog 1, actin-bundling protein a (Strongylocentrotus purpuratus) (fscn1a) antibody
  • fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) (Fscn1) antibody
  • fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) (FSCN1) antibody
  • fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) (Fscn1) antibody
  • AI663989 antibody
  • CG1536 antibody
  • CG15331 antibody
  • CG32858 antibody
  • Dmel\\CG32858 antibody
  • FAN1 antibody
  • fascin antibody
  • fascin-1 antibody
  • fs(1)A1057 antibody
  • fs(1)K418 antibody
  • fs(1)K473 antibody
  • fs(1)K743 antibody
  • fs(1)K1421 antibody
  • fs(1)M45 antibody
  • fscn antibody
  • fscn1 antibody
  • HSN antibody
  • MGC75811 antibody
  • p55 antibody
  • sb:cb589 antibody
  • Sn antibody
  • SNL antibody
  • zgc:153632 antibody

Protein level used designations for FSCN1

CG32858-PA , CG32858-PB , CG32858-PD , CG32858-PE , CG32858-PF , CG32858-PG , fascin , sn-PA , sn-PB , sn-PD , sn-PE , sn-PF , sn-PG , fascin-1 , fascin 1 , singed-like protein , 55 kDa actin-bundling protein , singed-like (fascin homolog, sea urchin)

GENE ID SPECIES
31717 Drosophila melanogaster
394733 Xenopus (Silurana) tropicalis
558271 Danio rerio
14086 Mus musculus
683788 Rattus norvegicus
397934 Xenopus laevis
6624 Homo sapiens
489880 Canis lupus familiaris
100286741 Sus scrofa
100733694 Cavia porcellus
507342 Bos taurus
416485 Gallus gallus
101108186 Ovis aries
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