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FCGR3A encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. Additionally we are shipping FCGR3A Proteins (24) and FCGR3A Kits (22) and many more products for this protein.
Showing 10 out of 288 products:
Human Polyclonal FCGR3A Primary Antibody for WB - ABIN657457
Dornan, Spleiss, Yeh, Duchateau-Nguyen, Dufour, Zhi, Robak, Moiseev, Dmoszynska, Solal-Celigny, Warzocha, Loscertales, Catalano, Afanasiev, Larratt, Rossiev, Bence-Bruckler, Geisler, Montillo, Wenger, Weisser: Effect of FCGR2A and FCGR3A variants on CLL outcome. in Blood 2010
Show all 2 references for ABIN657457
Human Monoclonal FCGR3A Primary Antibody for FACS, IHC (p) - ABIN1688969
Romano, Kusio-Kobialka, Foukas, Baumgaertner, Meyer, Ballabeni, Michielin, Weide, Romero, Speiser: Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients. in Proceedings of the National Academy of Sciences of the United States of America 2015
our method allows determining the CNV status of the FCGR locus, we identified association of CNV in FCGR3B to RA and showed a functional relationship between CNV in the FCGR3A gene and CD16A expression.
KRAS wild chemorefractory metastatic colorectal cancer patients with genotype FF of V158F can benefit from cetuximab based therapy
FcgammaRIIIA/FcgammaRIIA gene polymorphisms and HER-2 (show ERBB2 Antibodies) may have a role in antibody-dependent cellular cytotoxicity and clinical response to trastuzumab in breast cancer
PAR-2 (show F2RL1 Antibodies) expression is increased on CD14 (show NDUFA2 Antibodies)++CD16 (show CD16 Antibodies)+ monocytes in the peripheral blood of subjects with severe asthma and may be a biomarker of asthma severity.
This study demonstrated the biological importance of human IgG1-Fc Tyr (show TYR Antibodies)-296 for interactions with Fc gamma receptor III-A by protein engineering and X-ray structural analysis.
Data suggest that immune complexes (ICs (show DNAI1 Antibodies)) of FCGR3A (show CD16 Antibodies)-SYK (show SYK Antibodies) play critical role in activation of CD4 (show CD4 Antibodies)+ T-cells and thus in modulation of adaptive immunity; such ICs (show DNAI1 Antibodies) are present in blood from patients with systemic lupus erythematosus.
therapy with rituximab, cyclophosphamide and fludarabine resulted in a significant reduction in the number of non-classical CD14 (show NDUFA2 Antibodies)+CD16 (show CD16 Antibodies)++ monocytes and soluble form of CD163 (show CD163 Antibodies) but upregulation of membrane-associated monocyte CD163 (show CD163 Antibodies)
Data show that gains or losses in copy numbers of Fc gamma receptors FCGR3A (show CD16 Antibodies) were less frequent than for FCGR3B (show CD16 Antibodies) and FCGR2C.
Specific pro-inflammatory monocyte subpopulations positive for CD16 (show CD16 Antibodies) and the co-expressed chemokine receptor (show CCR1 Antibodies), CX3CR1 (show CX3CR1 Antibodies), are discriminative for chronic kidney disease stage 5 on hemodialysis patients.
we address of monocytes functional status through assessment of the patterns of expression of Fcgamma receptors CD64 (show FCGR1A Antibodies), CD32 (show FCGR2B Antibodies), CD16 (show CD16 Antibodies) and CD180 (show CD180 Antibodies) receptor on monocytes from CLL patients and healthy individuals using specific mAbs and flow cytometry.
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, Fc fragment of IgG, low affinity III, receptor for (CD16)
, Fc gamma receptor III-A
, Fc-gamma RIII-alpha
, Fc-gamma RIIIa
, Fc-gamma receptor III-2 (CD 16)
, Fc-gamma receptor IIIb (CD16)
, fc-gamma RIII
, igG Fc receptor III-2
, immunoglobulin G Fc receptor III
, low affinity immunoglobulin gamma Fc region receptor III-A
, neutrophil-specific antigen NA