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FCRL1 encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. Additionally we are shipping FCRL1 Proteins (7) and FCRL1 Kits (1) and many more products for this protein.
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FCRL1 (show FCRLA Antibodies) gene expression down-regulates in both Hashimoto and Graves disease patients compared to normal subjects.
Data show the Differences in high resolution melting analysis in promoters of tumor markers neuronal membrane glycoprotein M6-B (show GPM6B Antibodies), melanoma antigen family A12 (show MAGEA12 Antibodies) and immunoglobulin superfamily Fc receptor (show FCGRT Antibodies) indicated invasiveness of hepatocellular carcinoma.
Expression level of FCRL1 (show FCRLA Antibodies) gene in peripheral blood B-lymphocytes is significantly higher in patients with autoimmune diseases.
FcRH1 thus has the potential to serve as an activating coreceptor on B cells.
Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia.
Down-regulation of FCRL1 (show FCRLA Antibodies) is associated with acute lymphoblastic leukemia.
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants.
Fc receptor-like 1
, Fc receptor-like protein 1-like
, Fc receptor-like protein 1
, IFGP family protein 1
, fc receptor homolog 1
, fcR-like protein 1
, immune receptor translocation-associated protein 5
, immunoglobulin superfamily Fc receptor, gp42
, BXMAS1-like protein 1
, BXMAS1-like protein 1b