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Fibrinogen alpha Chain Proteins (FGA)

The protein encoded by FGA is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Additionally we are shipping Fibrinogen alpha Chain Antibodies (111) and Fibrinogen alpha Chain Kits (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FGA 2243 P02671
FGA 14161  
FGA 361969  
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Top Fibrinogen alpha Chain Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Rat His tag   100 μg Log in to see 11 to 13 Days
$704.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,181.83
Details
HOST_Escherichia coli (E. coli) Human His tag,S tag   100 μg Log in to see 11 to 13 Days
$492.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$684.50
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
$889.07
Details

FGA Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)
,
Rat (Rattus) ,

More Proteins for Fibrinogen alpha Chain (FGA) Interaction Partners

Human Fibrinogen alpha Chain (FGA) interaction partners

  1. Neutrophilic asthma patients and eosinophilic asthma patients had increased fibrinogen compared to controls.

  2. To novel fibrinogen mutations have been identified (Aa17GlyalphaCys and Aa381SeralphaPhe) that cosegregate with dysfibrinogenemia in seven family members of a Chinese pedigree.

  3. The study reports two novel mutations detected in the FGA and FGB (show FGB Proteins) genes in two patients with inherited hypofibrinogenemia.

  4. Nutrient overload-induced up-regulation of all three fibrinogen component subunits of the coagulation cascade provides a possible mechanism to explain the excess cardiovascular disease mortality observed in non-alcoholic fatty liver disease patients.

  5. An analysis of the results obtained in this study and a critical review of previously published data indicate that gene polymorphisms in FGA and FGB (show FGB Proteins) are not related to ischemic stroke in children

  6. Results support the idea that fibrinogen alphaC regions are involved in the thickening of fibrin fibers.

  7. The study identified a 5.9 kDa C-terminal fragment of the fibrinogen alpha chain as an early serum biomarker of fibrogenic processes in patients with liver disease.

  8. The Aalpha-Val360 related cross-sectionally to physiologic, radiologic, and symptomatic markers of disease severity of PiZZ alpha1-antitrypsin deficiency.

  9. Case Report: hepatocytes homozygous for a large FGA deletion can be genetically modified to restore Aalpha-chain protein expression and secrete a functional fibrinogen hexamer.

  10. High plasma D-dimer, fibrinogen, and platelet levels are associated with epithelial ovarian cancer independently of venous thromboembolism.

Cow (Bovine) Fibrinogen alpha Chain (FGA) interaction partners

  1. NMR solution structure of the bovine fibrinogen alphaC-domain fragment, including residues Aalpha374-538, reveals a type-I' beta-hairpin, restricted at the base by a C423-C453 disulfide linkage and a short turn preceding C423.

Mouse (Murine) Fibrinogen alpha Chain (FGA) interaction partners

  1. cellular fibrin uptake was diminished by elimination of CCR2-expressing cells.

  2. Mice expressing a mutant form of fibrinogen cannot support fibrin formation exhibit compromised antimicrobial host defense.

  3. Data indicate RU-505 as an effective inhibitor of the beta-amyloid (Abeta)-fibrinogen interaction.

  4. Fbg deficiency was associated with enhanced hepatic expression of the transcription factor early growth response-1 (show EGR1 Proteins).

Pig (Porcine) Fibrinogen alpha Chain (FGA) interaction partners

  1. Data suggest the potential compensatory role of fibrinogen in restoring coagulation function in vivo after hemorrhagic shock.

Fibrinogen alpha Chain (FGA) Protein Profile

Protein Summary

The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus.

Gene names and symbols associated with Fibrinogen alpha Chain Proteins (FGA)

  • fibrinogen alpha chain (FGA)
  • fibrinogen alpha chain (Fga)
  • Ac1873 protein
  • ENSMUSG00000059807 protein
  • Fba5e protein
  • Fib protein
  • Fib2 protein

Protein level used designations for Fibrinogen alpha Chain Proteins (FGA)

fibrinogen alpha chain , fibrinogen alpha chain-like , fibrinogen, A alpha polypeptide , fibrinogen A-alpha chain , fibrinogen, alpha polypeptide , carboxy-terminal region , fibrinogen A-alpha-chain , fibrinogen alpha subunit , fibrinogen alpha-E subunit , pre-fibrinogen alpha subunit

GENE ID SPECIES
100461464 Pongo abelii
100469401 Ailuropoda melanoleuca
100607544 Nomascus leucogenys
2243 Homo sapiens
522039 Bos taurus
14161 Mus musculus
475473 Canis lupus familiaris
100514666 Sus scrofa
361969 Rattus norvegicus
396307 Gallus gallus
100720646 Cavia porcellus
100069763 Equus caballus
100353616 Oryctolagus cuniculus
698244 Macaca mulatta
101102090 Ovis aries
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