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The protein encoded by FGB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Additionally we are shipping Fibrinogen beta Chain Kits (51) and Fibrinogen beta Chain Proteins (19) and many more products for this protein.
Showing 10 out of 116 products:
Human Monoclonal FGB Primary Antibody for ELISA, WB - ABIN969136
Vu, Bolton-Maggs, Parr, Morris, de Moerloose, Neerman-Arbez: Congenital afibrinogenemia: identification and expression of a missense mutation in FGB impairing fibrinogen secretion. in Blood 2003
Show all 2 Pubmed References
Human Polyclonal FGB Primary Antibody for IF (p), IHC (p) - ABIN1387626
Honda, Asada, Kageyama, Fukuda, Terada, Yasui, Sumi, Koyama, Ishiko, Sugawa: Protein Complex of Fibrinogen Gamma Chain and Complement Factor H in Ovarian Cancer Patient Plasma. in Anticancer research 2017
elevated levels of plasma homocysteine /homocysteine thiolactone contribute to AD pathology via the Abeta (show APP Antibodies)-fibrin(ogen) interaction
Heterozygous FV Leiden, homozygous PAI-1 4G/4G, heterozygous MTHFR C677T, homozygous MTHFR A1298C, as much as the combined thrombophilic genotypes MTHFR 677T + ACE Iota/D, MTHFR 677T/1298C + ACE D/D, ACE I/D + b-fibrinogen -455 G/A, FV HR2 + b-fibrinogen -455 G/A showed a correlation as risk factors for Recurrent pregnancy loss.
procoagulant changes in fibrin metastructure appear to result from excessive carbonylation of fibrinogen, which may compensate for a decrease in fibrinogen level in patients with cirrhosis
Prognostic impact of plasma fibrinogen levels in patients with esophageal squamous cell carcinoma
Data indicate that repeated measurement after five hours showed a statistical significant difference for the fractional synthesis rate of fibrinogen but not for albumin (show ALB Antibodies).
a tight cluster of alternating multiple splicing regulatory elements and U1 snRNA binding sites controls cryptic splice donor usage throughout the human fibrinogen Bbeta-chain gene (FGB) exon 7
The high preoperative peripheral serum fibrinogen level was related to poor survival in penile cancer patients, suggeting fibrinogen may serve as a powerful predictor of cancer specific survival (CSS (show CMAS Antibodies)) in penile cancer patients.
The plasma fibrinogen level was found to be a possible biomarker for clinical response to chemotherapy and postoperative metastasis or death in advanced breast cancer patients who received neoadjuvant chemotherapy
Data suggest that, in the binding of fibrin beta N-domains and the (1-8) peptide fragment of VLDLR (very low density lipoprotein receptor (show VLDLR Antibodies)), the second and third Lys (show LYZ Antibodies)/Arg clusters in fibrin make major contributions to this interaction while the contribution of the first cluster is moderate.
The novel missense mutation in the FGB gene causes afibrinogenemia most probably by affecting the secretion of the fibrinogen beta-chain.
Data suggest that the interaction between Abeta and fibrinogen may be an important contributor to the vascular abnormalities found in Alzheimer's disease.
beta(3) integrin, thrombin (show F2 Antibodies), and Ca(2 (show CA2 Antibodies)+) play critical roles in platelet aggregation without fibrinogen or VWF (show VWF Antibodies)
Data suggest the potential compensatory role of fibrinogen in restoring coagulation function in vivo after hemorrhagic shock.
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
fibrinogen, B beta polypeptide
, fibrinogen beta chain
, B fibrinopeptide
, fibrinogen, beta chain
, B beta polypeptide
, fibrinogen, beta polypeptide
, liver regeneration-related protein LRRG036/LRRG043/LRRG189
, fibrinogen beta chain-like
, fibrinogen B-beta subunit