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Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression.. Additionally we are shipping FGF15 Antibodies (9) and FGF15 Proteins (7) and many more products for this protein.
Showing 2 out of 9 products:
Mouse (Murine) FGF15 ELISA Kit for Competition ELISA - ABIN481717
Assini, Mulvihill, Burke, Sutherland, Telford, Chhoker, Sawyez, Drangova, Adams, Kharitonenkov, Pin, Huff: Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21. in Endocrinology 2015
This study reveals SHP (show LAMC1 ELISA Kits) as a global transcriptional partner of SREBP-2 (show SREBF2 ELISA Kits) in regulation of sterol biosynthetic gene networks and provides a potential mechanism for cholesterol-lowering action of FGF19 (show FGF19 ELISA Kits).
Protective effects of farnesoid X receptor on hepatic lipid accumulation are mediated by hepatic FXR (show NR1H4 ELISA Kits) and are independent of intestinal FGF15 signaling.
Intestinal PPARalpha (show PPARA ELISA Kits)-UDP- Glucuronyltransferases and downstream FXR (show NR1H4 ELISA Kits)-FGF15 signalling play vital roles in control of bile acid homeostasis and the pathological development of colitis.
a direct role of intestinal FGF15/19 in the regulation of SI P450 (show POR ELISA Kits) expression and may have profound implications for the prediction of drug exposure in patients with compromised hepatic P450 (show POR ELISA Kits) function
findings implicate the brain in the antidiabetic action of systemic FGF19 (show FGF19 ELISA Kits) and establish the brain's capacity to rapidly, potently, and selectively increase insulin (show INS ELISA Kits)-independent glucose disposal
Ileal Fibroblast Growth Factor-15 (FGF15) expression was significantly reduced in Asbt (show SLC10A2 ELISA Kits)(-/-)apoE (show APOE ELISA Kits)(-/-) mice and was inversely correlated with expression of hepatic cholesterol 7-hydroxylase (Cyp7a1 (show CYP7A1 ELISA Kits)).
HNF4alpha (show HNF4A ELISA Kits) and LRH-1 (show NR5A2 ELISA Kits) promote active transcription histone marks on the Cyp7a1 (show CYP7A1 ELISA Kits) promoter that are reversed by FGF19 (show FGF19 ELISA Kits) in a SHP (show LAMC1 ELISA Kits)-dependent manner
Total ileal FGF15 expression was elevated almost 20-fold in Ostalpha (show OSTALPHA ELISA Kits)(-/-) mice as a result of increased villus epithelial cell number and ileocyte FGF15 protein expression
generated a variant of FGF19 (show FGF19 ELISA Kits), FGF19 (show FGF19 ELISA Kits)-7, that has altered receptor specificity with a strong bias toward FGFR1c
Differential specificity of endocrine FGF19 (show FGF19 ELISA Kits) and FGF21 (show FGF21 ELISA Kits) to FGFR1 (show FGFR1 ELISA Kits) and FGFR4 (show FGFR4 ELISA Kits) in complex with KLB (show KLB ELISA Kits).
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression.
, fibroblast growth factor 15