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Fibronectin 1 Proteins (FN1)

FN1 encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Additionally we are shipping Fibronectin Antibodies (519) and Fibronectin Kits (124) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FN1 2335 P02751
FN1 14268 P11276
FN1 25661  
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Top Fibronectin Proteins at

Showing 10 out of 58 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
HOST_Human Human Un-conjugated   5 mg Log in to see 5 to 6 Days
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 9 to 11 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
HOST_Human Human Un-conjugated   1 mg Log in to see 2 to 3 Days
Mouse Mouse Un-conjugated   1 mg Log in to see 2 to 3 Days
Yeast Notophthalmus viridescens His tag   1 mg Log in to see 56 to 66 Days

FN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
Mouse (Murine) ,

Rat (Rattus) ,

Top referenced Fibronectin Proteins

  1. Human Fibronectin Protein expressed in Human Cells - ABIN2002555 : Liu, Fedorov, Pollard, Lattman, Almo, Magnus: Crystal packing induces a conformational change in profilin-I from Acanthamoeba castellanii. in Journal of structural biology 1998 (PubMed)
    Show all 6 references for ABIN2002555

  2. Human Fibronectin Protein expressed in Human - ABIN377072 : Ferizi, Leonhardt, Meggle, Aneja, Rudolph, Plank, Rädler: Stability analysis of chemically modified mRNA using micropattern-based single-cell arrays. in Lab on a chip 2015 (PubMed)
    Show all 6 references for ABIN377072

  3. Human Fibronectin Protein expressed in Human - ABIN491241 : Zhu, Gladson, White, Ding, Stewart, Jin, Chapman, Olman: Urokinase receptor mediates lung fibroblast attachment and migration toward provisional matrix proteins through interaction with multiple integrins. in American journal of physiology. Lung cellular and molecular physiology 2009 (PubMed)

  4. Mouse (Murine) Fibronectin Protein expressed in Mouse - ABIN491242 : Reheman, Yang, Zhu, Jin, He, Spring, Bai, Gross, Freedman, Ni: Plasma fibronectin depletion enhances platelet aggregation and thrombus formation in mice lacking fibrinogen and von Willebrand factor. in Blood 2009 (PubMed)

More Proteins for Fibronectin 1 (FN1) Interaction Partners

Zebrafish Fibronectin 1 (FN1) interaction partners

  1. Injection of alpha5beta1 protein rescued the Fibronectin layer and then the myocardial precursor migration in snai1b knockdown embryos.

  2. Fibronectin, a main component of the extracellular matrix, is induced and deposited after cardiac damage

  3. Fibronectin deficiency resulted in a dramatic reduction of mesoderm accompanied by endodermal expansion in zebrafish embryos.

  4. Data indicate that focal adhesion kinase (FAK) activity may be a mediator of the integrin alpha5/Fn1 interaction during zebrafish lens fiber morphogenesis.

  5. reduction of fn1 function enables rescue of cardiac fusion in hand2 (show HAND2 Proteins) mutants

  6. Fibronectin regulates epithelial organization during myocardial migration in zebrafish.

Human Fibronectin 1 (FN1) interaction partners

  1. An observed increase in PLD activity was mediated through boosting the binding of PLD with dynamin (show DNM1 Proteins) which in turn facilitated fibronectin-induced cell spreading.

  2. The pathogenic H5N1 and H7N9 influenza virus variants cause more severe deregulation of NRF2 (show GABPA Proteins) and fibronectin in host epithelial cells than the less pathogenic H1N1 variant.

  3. Fibronectin binding to heparan sulfate mediates exosome-cell interactions in Myeloma.

  4. that strong FN1 promoter activity drives inappropriate expression of the biologically active portion of EGF (show EGF Proteins)

  5. Serum fibronectin was increased in T2DM patients compared to controls, and in patients with diabetic nephropathy, compared to diabetic patients without nephropathy. Fibronectin increased with nephropathy severity.

  6. These results suggest that MUC5B production can be regulated by ECM (show MMRN1 Proteins) components and that MUC5B is upregulated by fibronectin and laminin via the integrin, ERK (show EPHB2 Proteins), and NF-kappaB (show NFKB1 Proteins) dependent pathway.

  7. The results indicated that MMP-9 (show MMP9 Proteins)-degraded Fibronectin can adjust constituents of the avb6 heterodimers at the early phase and significantly elevate amounts of b6 integrin subunits at a later period

  8. Serum- and CSF (show CSF2 Proteins)-FN levels constitute a potential clinical diagnostic biomarker for epilepsy and could also be used for differential diagnosis.

  9. the correlation between placental DNAm of INHBA (show INHBA Proteins)/FN1 and maternal serum INHA (show INHA Proteins)/FN1 levels indicate that DNAm may be a useful tool to identify novel biomarkers for adverse pregnancy outcomes in some cases.

  10. Fn Msp (show MSMB Proteins) iv polymorphism appeared to be associated with diabetic nephropathy susceptibility.

Mouse (Murine) Fibronectin 1 (FN1) interaction partners

  1. Fibrillar cellular fibronectin supports platelet adhesion, activation, aggregation and procoagulant activity via the interplay of a series of receptors i.e. integrins alpha5beta1 and alphaIIbbeta3, the GPIb-V-IX complex, GPVI (show GP6 Proteins) and Toll-like receptor 4 (show TLR4 Proteins).

  2. Fn1 synthesized by the neural crest mediated morphogenesis of the aortic arch artery and differentiation of neural crest cells into vascular smooth muscle cells by regulating Notch (show NOTCH1 Proteins) signaling.

  3. A novel mechanism of transcriptional regulation of fibronectin through CREB (show CREB1 Proteins).

  4. Hypercholesterolemic mice deficient in extra domain A of fibronectin exhibit reduced cerebral thrombosis.

  5. the epithelial interaction between fibronectin and beta1 integrin is important for ameloblast differentiation and enamel formation.

  6. An (as yet unknown) integrin alpha5-dependent signal extrinsic to the pharyngeal endothelium mediates the formation of the 4th pharyngeal arch arteries through fibronectin.

  7. TLR4 (show TLR4 Proteins) signaling contributes to EDA (show EDA Proteins)(+)-FN-mediated exacerbation of atherosclerosis.

  8. 5-HT (show DDC Proteins)) inhibits Factor XIII (show UGDH Proteins)-A-mediated plasma fibronectin matrix assembly and crosslinking in osteoblast cultures via direct competition with transamidation

  9. The DP-4 (show TFDP3 Proteins) peptide activated Fn and enhanced cell adhesion activity

  10. fibronectin secretion has a role in mesothelial cells promotion of early ovarian cancer metastasis

Cow (Bovine) Fibronectin 1 (FN1) interaction partners

  1. plasma FN assembly into bone matrix in vitro requires FXIIIA transglutaminase activity making pFN assembly an active, osteoblast-mediated process.

  2. Fetal and adult human skin fibroblasts retain their differential proliferative response to TGF-beta (show TGFB1 Proteins) when cultured in the presence of fibronectin and unpolymerized or polymerized collagen.

  3. Putative function of fibronectin and its receptor (integrin alpha(5 (show ITGA5 Proteins))beta(1)) in male and female gametes during bovine fertilization in vitro.

  4. These results highlight a crucial role for caveolin-1 (show CAV1 Proteins) in negative regulation of membrane microdomain mobility, thereby affecting endocytosis of bacteria-engaged integrins.

  5. P. multocida-Fn interaction may play a role in the bacterium adherence to host cells, and this may be mediated by bacterial surface proteins with preferential affinity for the Hep-1 binding domain of Fn

Horse (Equine) Fibronectin 1 (FN1) interaction partners

  1. The expression of extracellular matrix molecules fibronectin and osteopontin (show SPP1 Proteins) in vitreous and retina samples in autoimmune uveitis was investigated.

Pig (Porcine) Fibronectin 1 (FN1) interaction partners

  1. The obtained results suggest that propolis modifies fibronectin metabolism in the course of wound healing process.

  2. The relationship between hyaluronan synthesis and levels of versican (show Vcan Proteins), fibronectin and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.

  3. fibronectin has a cryptic binding site for tenascin (show TNC Proteins)

Fibronectin (FN1) Protein Profile

Protein Summary

This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.

Gene names and symbols associated with Fibronectin 1 Proteins (FN1)

  • fibronectin 1 (FN1)
  • fibronectin 1 (fn1)
  • fibronectin 1 (Fn1)
  • CIG protein
  • E330027I09 protein
  • ED-B protein
  • fb80d10 protein
  • FIBNEC protein
  • fibronectin protein
  • FINC protein
  • Fn protein
  • fn-1 protein
  • FN1 protein
  • fn2 protein
  • FNZ protein
  • GFND protein
  • GFND2 protein
  • LETS protein
  • MSF protein
  • wu:fb80d10 protein

Protein level used designations for Fibronectin 1 Proteins (FN1)

fibronectin 1 , gene C , fibronectin , fn1l , nat , natter , fibronectin-like , cold-insoluble globulin , migration-stimulating factor , FN , cumulus cell-specific fibronectin 1 transcript , embryo-specific fibronectin 1 transcript , fibronectin ED-A- region , fibronectin variable region

459926 Pan troglodytes
595087 Xenopus (Silurana) tropicalis
613269 Macaca mulatta
100005469 Danio rerio
100405983 Callithrix jacchus
100464134 Ailuropoda melanoleuca
100601303 Nomascus leucogenys
2335 Homo sapiens
396133 Gallus gallus
14268 Mus musculus
25661 Rattus norvegicus
280794 Bos taurus
403845 Canis lupus familiaris
100034189 Equus caballus
397620 Sus scrofa
100732865 Cavia porcellus
100328589 Oryctolagus cuniculus
397744 Xenopus laevis
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