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Fibronectin 1 Proteins (FN1)

FN1 encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Additionally we are shipping Fibronectin Antibodies (216) and Fibronectin Kits (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FN1 2335 P02751
FN1 14268 P11276
FN1 25661  
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Top Fibronectin Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$173.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 11 Days
$100.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Chicken His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,174.33
Details
HOST_Escherichia coli (E. coli) Rat His tag   100 μg Log in to see 11 to 13 Days
$316.80
Details
HOST_Human Human Un-conjugated   1 mg Log in to see 6 to 11 Days
$485.71
Details

FN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced Fibronectin Proteins

  1. Human Fibronectin Protein expressed in Human Cells - ABIN2002555 : Liu, Fedorov, Pollard, Lattman, Almo, Magnus: Crystal packing induces a conformational change in profilin-I from Acanthamoeba castellanii. in Journal of structural biology 1998 (PubMed)
    Show all 6 references for ABIN2002555

More Proteins for Fibronectin 1 (FN1) Interaction Partners

Zebrafish Fibronectin 1 (FN1) interaction partners

  1. Injection of alpha5beta1 protein rescued the Fibronectin layer and then the myocardial precursor migration in snai1b knockdown embryos.

  2. Fibronectin, a main component of the extracellular matrix, is induced and deposited after cardiac damage

  3. Fibronectin deficiency resulted in a dramatic reduction of mesoderm accompanied by endodermal expansion in zebrafish embryos.

  4. Data indicate that focal adhesion kinase (FAK) activity may be a mediator of the integrin alpha5/Fn1 interaction during zebrafish lens fiber morphogenesis.

  5. reduction of fn1 function enables rescue of cardiac fusion in hand2 (show HAND2 Proteins) mutants

  6. Fibronectin regulates epithelial organization during myocardial migration in zebrafish.

Human Fibronectin 1 (FN1) interaction partners

  1. FN and HtrA1 (show HTRA1 Proteins) are localized in the placental key growth zones suggesting a pivotal role in maintaining the balance among the molecules involved in the placental development and differentiation

  2. fibronectin as a potential indicator of an extracellular matrix remodeling related to the hypertrophic cardiomyopathy

  3. Overexpression of FN1 is associated with lung cancer.

  4. Missense variant in FN1 gene is associated with familial hematuria.

  5. HMGA2 promoted colorectal cancer metastasis and epithelial-mesenchymal transition via activation of the FN1 and IL11 (show IL11 Proteins)/STAT3 (show STAT3 Proteins) signaling pathways.

  6. Urolithin A incubation caused the up-regulation of CDKN1A and down-regulation of FN-1 in prostate cancer cells.

  7. Crosslinker-mediated immobilization showed significant fibronectin grafting on surfaces, which provided K562 cell adhesion and growth advantage. siRNA nanoparticle silencing was similarly effective on fibronectin -adhered and suspension-growing K562 cells

  8. Data suggest fetal fibronectin is up-regulated in vaginal secretions of women with signs of preterm labor (24-34 weeks) who deliver before term (that is, result in premature birth) compared to those who deliver at term; this finding holds for blind vaginal swabs collected without aid of speculum or routine cervicovaginal swabs; study was conducted at large maternity hospital in Egypt.

  9. Pharmacophore-based screening targeted at upregulated FN1, MMP-9 (show MMP9 Proteins), APP (show APP Proteins) reveals therapeutic compounds for nasopharyngeal carcinoma.

  10. An observed increase in PLD activity was mediated through boosting the binding of PLD with dynamin (show DNM1 Proteins) which in turn facilitated fibronectin-induced cell spreading.

Mouse (Murine) Fibronectin 1 (FN1) interaction partners

  1. The results very comprehensively demonstrate distinct signaling pathways that regulate microfilament organization, lamellipodial structures, spreading, and movement of cells plated on galectin-3 (show LGALS3 Proteins) as opposed to fibronectin.

  2. Thus, similarly to growth factor signaling, fibronectin matrix assembly during early development can be both autocrine and paracrine.

  3. These results suggest that the Rac1 regulation of the FN arrangement is involved in retinoic acid-induced cleft palate.

  4. Fibrillar cellular fibronectin supports platelet adhesion, activation, aggregation and procoagulant activity via the interplay of a series of receptors i.e. integrins alpha5beta1 and alphaIIbbeta3, the GPIb-V-IX complex, GPVI (show GP6 Proteins) and Toll-like receptor 4 (show TLR4 Proteins).

  5. Fn1 synthesized by the neural crest mediated morphogenesis of the aortic arch artery and differentiation of neural crest cells into vascular smooth muscle cells by regulating Notch (show NOTCH1 Proteins) signaling.

  6. A novel mechanism of transcriptional regulation of fibronectin through CREB (show CREB1 Proteins).

  7. Hypercholesterolemic mice deficient in extra domain A of fibronectin exhibit reduced cerebral thrombosis.

  8. the epithelial interaction between fibronectin and beta1 integrin is important for ameloblast differentiation and enamel formation.

  9. An (as yet unknown) integrin alpha5-dependent signal extrinsic to the pharyngeal endothelium mediates the formation of the 4th pharyngeal arch arteries through fibronectin.

  10. TLR4 (show TLR4 Proteins) signaling contributes to EDA (show EDA Proteins)(+)-FN-mediated exacerbation of atherosclerosis.

Cow (Bovine) Fibronectin 1 (FN1) interaction partners

  1. plasma FN assembly into bone matrix in vitro requires FXIIIA transglutaminase activity making pFN assembly an active, osteoblast-mediated process.

  2. Fetal and adult human skin fibroblasts retain their differential proliferative response to TGF-beta (show TGFB1 Proteins) when cultured in the presence of fibronectin and unpolymerized or polymerized collagen.

  3. Putative function of fibronectin and its receptor (integrin alpha(5 (show ITGA5 Proteins))beta(1)) in male and female gametes during bovine fertilization in vitro.

  4. These results highlight a crucial role for caveolin-1 (show CAV1 Proteins) in negative regulation of membrane microdomain mobility, thereby affecting endocytosis of bacteria-engaged integrins.

  5. P. multocida-Fn interaction may play a role in the bacterium adherence to host cells, and this may be mediated by bacterial surface proteins with preferential affinity for the Hep-1 binding domain of Fn

Horse (Equine) Fibronectin 1 (FN1) interaction partners

  1. The expression of extracellular matrix molecules fibronectin and osteopontin (show SPP1 Proteins) in vitreous and retina samples in autoimmune uveitis was investigated.

Pig (Porcine) Fibronectin 1 (FN1) interaction partners

  1. The obtained results suggest that propolis modifies fibronectin metabolism in the course of wound healing process.

  2. The relationship between hyaluronan synthesis and levels of versican (show Vcan Proteins), fibronectin and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.

  3. fibronectin has a cryptic binding site for tenascin (show TNC Proteins)

Fibronectin (FN1) Protein Profile

Protein Summary

This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.

Gene names and symbols associated with Fibronectin 1 Proteins (FN1)

  • fibronectin 1 (FN1)
  • fibronectin 1 (fn1)
  • fibronectin 1 (Fn1)
  • CIG protein
  • E330027I09 protein
  • ED-B protein
  • fb80d10 protein
  • FIBNEC protein
  • fibronectin protein
  • FINC protein
  • Fn protein
  • fn-1 protein
  • FN1 protein
  • fn2 protein
  • FNZ protein
  • GFND protein
  • GFND2 protein
  • LETS protein
  • MSF protein
  • wu:fb80d10 protein

Protein level used designations for Fibronectin 1 Proteins (FN1)

fibronectin 1 , gene C , fibronectin , fn1l , nat , natter , fibronectin-like , cold-insoluble globulin , migration-stimulating factor , FN , cumulus cell-specific fibronectin 1 transcript , embryo-specific fibronectin 1 transcript , fibronectin ED-A- region , fibronectin variable region

GENE ID SPECIES
459926 Pan troglodytes
595087 Xenopus (Silurana) tropicalis
613269 Macaca mulatta
100005469 Danio rerio
100405983 Callithrix jacchus
100464134 Ailuropoda melanoleuca
100601303 Nomascus leucogenys
2335 Homo sapiens
396133 Gallus gallus
14268 Mus musculus
25661 Rattus norvegicus
280794 Bos taurus
403845 Canis lupus familiaris
100034189 Equus caballus
397620 Sus scrofa
100732865 Cavia porcellus
100328589 Oryctolagus cuniculus
397744 Xenopus laevis
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