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anti-Filamin Binding LIM Protein 1 (FBLIM1) Antibodies

FBLIM1 encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. Additionally we are shipping FBLIM1 Kits (7) and FBLIM1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FBLIM1 54751 Q8WUP2
FBLIM1 74202 Q71FD7
FBLIM1 362650  
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Top anti-FBLIM1 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB FBLIM1 Antibody (C-term)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the FBLIM1 antibody detected the FBLIM1 protein (arrow). FBLIM1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FBLIM1 Antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue reacted with FBLIM1 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of FBLIM1 Antibody (C-term) in A549 cell line lysates (35ug/lane). This demonstrates the FBLIM1 antibody detected the FBLIM1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated WB FBLIM1 monoclonal antibody (M03), clone 3F8. Western Blot analysis of FBLIM1 expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of FBLIM1 expression in transfected 293T cell line by FBLIM1 monoclonal antibody (M10), clone 5E11. Lane 1: FBLIM1 transfected lysate(41 KDa). Lane 2: Non-transfected lysate. FBLIM1 monoclonal antibody (M10), clone 5E11 Western Blot analysis of FBLIM1 expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB FBLIM1 monoclonal antibody (M10), clone 5E11 Western Blot analysis of FBLIM1 expression in HepG2 . Western Blot analysis of FBLIM1 expression in transfected 293T cell line by FBLIM1 monoclonal antibody (M10), clone 5E11.Lane 1: FBLIM1 transfected lysate(41 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.55 KDa) . 50 μL Log in to see 9 Days
$298.57
Details

FBLIM1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
,
,
, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-FBLIM1 Antibodies

  1. Human Monoclonal FBLIM1 Primary Antibody for WB - ABIN393973 : Zhao, Zhang, Ithychanda, Tu, Chen, Qin, Wu: Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling. in The Journal of biological chemistry 2009 (PubMed)
    Show all 5 references for ABIN393973

  2. Human Monoclonal FBLIM1 Primary Antibody for WB - ABIN394293 : Ithychanda, Das, Ma, Ding, Wang, Gupta, Wu, Plow, Qin: Migfilin, a molecular switch in regulation of integrin activation. in The Journal of biological chemistry 2009 (PubMed)
    Show all 5 references for ABIN394293

  3. Human Polyclonal FBLIM1 Primary Antibody for EIA, IHC (p) - ABIN952270 : Lad, Jiang, Ruskamo, Harburger, Ylänne, Campbell, Calderwood: Structural basis of the migfilin-filamin interaction and competition with integrin beta tails. in The Journal of biological chemistry 2008 (PubMed)
    Show all 3 references for ABIN952270

  4. Human Monoclonal FBLIM1 Primary Antibody for ELISA, WB - ABIN565770 : Has, Herz, Zimina, Qu, He, Zhang, Wen, Gache, Aumailley, Bruckner-Tuderman: Kindlin-1 Is required for RhoGTPase-mediated lamellipodia formation in keratinocytes. in The American journal of pathology 2009 (PubMed)

More Antibodies against FBLIM1 Interaction Partners

Human Filamin Binding LIM Protein 1 (FBLIM1) interaction partners

  1. the present study emphasizes for the first time to our knowledge the role of Migfilin in osteoarthritis(OA) and highlights the importance of cell-ECM (show MMRN1 Antibodies) adhesion proteins in OA pathogenesis.

  2. Migfilin expression is reduced in breast cancer.

  3. alpha-parvin (show PARVA Antibodies), beta-parvin (show PARVB Antibodies) and migfilin were expressed in tumor cells in 53%, 2%, 28% and 53% of effusions and 57%, 20%, 83% and 25% of solid lesions, respectively.

  4. Migfilin positively modulates the expression and activity of epidermal growth factor receptor (show EGFR Antibodies), and Migfilin-mediated migration and invasion depend on epidermal growth factor receptor (show EGFR Antibodies)-induced PLC (show HSPG2 Antibodies)-gamma and STAT3 (show STAT3 Antibodies)-signaling pathways.

  5. Migfilin promoted beta-catenin (show CTNNB1 Antibodies) degradation by reinforcing the association between beta-catenin (show CTNNB1 Antibodies) and GSK-3beta (show GSK3b Antibodies).

  6. Migfilin can activate beta1, beta2 and beta3 integrins and promote integrin mediated responses while migfilin depletion impairs the spreading and migration of endothelial cells

  7. The association between filamin B (show FLNB Antibodies) and FBLP-1 may play a hitherto unknown role in cytoskeletal function, cell adhesion, and cell motility.

  8. Migfilin has a role in interacting with vasodilator-stimulated phosphoprotein (VASP (show VASP Antibodies)) and regulates VASP (show VASP Antibodies) localization to cell-matrix adhesions and migration

  9. Results suggest a role for cytoplasmic migfilin in the progression of leiomyosarcomas (LMS) and identify cytoplasmic migfilin as a potentially important biological marker for human LMS progression.

  10. Loss-of-function mutations in KIND1 (show FERMT1 Antibodies) result in marked variability in kindlin-1 (show FERMT1 Antibodies) immunolabeling in Kindler syndrome skin, which is mirrored by similar changes in kindlin-2 (show FERMT2 Antibodies) and migfilin immunoreactivity.

Mouse (Murine) Filamin Binding LIM Protein 1 (FBLIM1) interaction partners

  1. Suggest migfilin regulates cardiac hypertrophy in transverse aortic constriction.

  2. C-terminal LIM (show PDLIM5 Antibodies) domains of migfilin dictate its focal adhesion localization, and these domains mediate an interaction with kindlin in vitro and in cells, demonstrating that kindlin is important for normal migfilin dynamics.

  3. results identify FBLP-1 as a key regulator of bone homeostasis and suggest that FBLP-1 functions in this process through modulating both the intrinsic properties of OB/BMSCs (i.e., BMSC-extracellular matrix adhesion and migration

  4. This study demonistrated that a molecular mechanism whereby FlnA (show FLNA Antibodies) loss impaired G2 to M phase entry, leading to cell cycle prolongation, compromised neural progenitor proliferation, and reduced brain size.

  5. The findings indicate that the roles of migfilin are functionally redundant during mouse development and tissue homeostasis.

  6. results suggest that a novel LIM protein (show PDLIM1 Antibodies) Cal (show S100A11 Antibodies) induces cardiomyocyte differentiation through its dynamic intracellular shuttling and association with CSX/NKX2-5 (show NKX2-5 Antibodies)

  7. analysis of the migfilin-filamin (show FLNA Antibodies) interaction and competition with integrin beta 7 (show ITGB7 Antibodies) tails

FBLIM1 Antigen Profile

Protein Summary

This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with FBLIM1

  • filamin binding LIM protein 1 (FBLIM1) antibody
  • filamin binding LIM protein 1 (fblim1) antibody
  • filamin binding LIM protein 1 (Fblim1) antibody
  • 2410043F08Rik antibody
  • Cal antibody
  • FBLIM1 antibody
  • FBLP-1 antibody
  • Fblp1 antibody
  • Gt10 antibody
  • migfilin antibody
  • migfilin(s) antibody

Protein level used designations for FBLIM1

filamin binding LIM protein 1 , filamin-binding LIM protein-1 , FBLP-1 , filamin-binding LIM protein 1 , CSX-associated LIM , MIG2-interacting protein , migfilin , mitogen-inducible 2 interacting protein , mitogen-inducible 2-interacting protein

GENE ID SPECIES
419458 Gallus gallus
608618 Canis lupus familiaris
740207 Pan troglodytes
100137707 Xenopus laevis
100174248 Pongo abelii
54751 Homo sapiens
74202 Mus musculus
767833 Bos taurus
362650 Rattus norvegicus
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