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anti-Formin 2 (FMN2) Antibodies

Formin homology (FH) domain proteins (see FMN1\; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity.[supplied by OMIM, Apr 2010].. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FMN2 56776 Q9NZ56
FMN2 54418 Q9JL04
FMN2 289262  
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Top anti-Formin 2 Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using FMN2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, WB FMN2 polyclonal antibody (A01), Lot # 060726QCS1 Western Blot analysis of FMN2 expression in K-562 . Western Blot detection against Immunogen (37 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IHC (p), ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IHC (p) 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged FMN2 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Log in to see 14 Days
$201.19
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged FMN2 is 0.3 ng/ml as a capture antibody. Western Blot analysis of FMN2 expression in transfected 293T cell line by FMN2 monoclonal antibody (M06), clone 1C2.Lane 1: FMN2 transfected lysate (Predicted MW: 11.11 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details

FMN2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,
,
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Mouse (Murine) , ,


Rat (Rattus)


Top referenced anti-Formin 2 Antibodies

  1. Human Polyclonal Formin 2 Primary Antibody for ELISA, WB - ABIN566042 : Belin, Lee, Mullins: DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-½ that promotes efficient DNA repair. in eLife 2015 (PubMed)

More Antibodies against Formin 2 Interaction Partners

Human Formin 2 (FMN2) interaction partners

  1. Disease causing mutations in inverted formin 2 (show INF2 Antibodies) regulate its binding to G-actin (show ACTB Antibodies), F-actin capping protein (CapZ (show CAPZB Antibodies) alpha-1 (show CAPZA1 Antibodies)) and profilin 2 (show PFN2 Antibodies).

  2. This DNA damage-induced nuclear actin assembly requires two biologically and physically linked nucleation factors: Formin-2 and Spire-1 (show SPIRE1 Antibodies)/Spire-2.

  3. We therefore characterized co-expressed Spir-2 (show SPIRE1 Antibodies) and Fmn-2 fluorescent protein fusions . The data corroborate a model according to which Spir-2 (show SPIRE1 Antibodies) exists in two different states, a cytosolic monomeric conformation and a membrane-bound state

  4. FMN2 mutations link intellectual disability either directly or indirectly to the regulation of actin-mediated synaptic spine density.

  5. miR-335 regulates the expression of at least five formin family members, three of which are validated, FMNL3, FMN2 and DAAM2.

  6. FMN2 is a crucial protein involved in the control of p21 (show CDKN1A Antibodies).

  7. results identify FMN2 as a crucial component in the regulation of p21 (show CDKN1A Antibodies) and consequent oncogene (show RAB1A Antibodies)/stress-induced cell-cycle arrest in human cells.

  8. analysis of the molecular basis of the Spir1/formin-2 interaction

  9. FMN2 was characterized at human chromosome 1q43.

  10. It is likely that FMN2 has the same function as Fmn2 in the mouse, i.e., maintenance of the meiotic spindle. Identification of patients with meiosis I arrest is necessary to determine whether FMN2 mutations are a cause of unexplained infertility.

Mouse (Murine) Formin 2 (FMN2) interaction partners

  1. Fmn2 as a mediator of actin bundle integrity, enabling efficient force transmission to the adhesion sites.

  2. Data suggest formin homology domain (FH2) of Fmn2 binds actin at filament barbed end as weak capper and plays a role in displacing WASP homology domain 2 (WH2) domains of Spire-1 from actin; competitive binding of Fmn2 vs Spire-1 aids actin assembly.

  3. Spire recruits Fmn2 and facilitates its association with actin filaments barbed ends.

  4. Results suggest that the regulation of microtubule acetylation is likely a general formin (show FMN1 Antibodies) activity.

  5. analysis of the molecular basis of the Spir1/formin-2 interaction

  6. Spire1 (show SPIRE1 Antibodies) and Spire2 (show SPIRE2 Antibodies) cooperate with Formin-2 (Fmn2) to nucleate actin filaments in mouse oocytes.

  7. High formin 2 levels at meiosis I entry induce meshwork maintenance, leading to equal forces being exerted on the chromosomes, preventing spindle migration.

  8. Gene profiling of Fmn2 in Graffi murine leukemia virus-induced lymphoid leukemias suggest its important role in leukemogenesis.

  9. Fmn2 is a candidate in a QTL hotspot associated with neurobehavioral traits and gene expression in the mouse brain. Hippocampal pyramidal neurons exhibit distinct and fine granular immunoreactivity for FMN2.

  10. formin-2 is a maternal-effect (show NLRP5 Antibodies) gene that is expressed in oocytes and is required for progression through metaphase of meiosis I

Formin 2 (FMN2) Antigen Profile

Protein Summary

Formin homology (FH) domain proteins (see FMN1\; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity.

Gene names and symbols associated with anti-Formin 2 (FMN2) Antibodies

  • formin 2 (PVX_123615) antibody
  • formin 2 (PKH_143610) antibody
  • formin 2 (FMN2) antibody
  • formin 2 (Fmn2) antibody
  • AU024104 antibody

Protein level used designations for anti-Formin 2 (FMN2) Antibodies

formin 2 , formin-2

GENE ID SPECIES
5476594 Plasmodium vivax Sal-1
7323284 Plasmodium knowlesi strain H
56776 Homo sapiens
54418 Mus musculus
775973 Gallus gallus
490366 Canis lupus familiaris
289262 Rattus norvegicus
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