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G Protein-Coupled Receptor 132 Proteins (GPR132)

Receptor for an unknown ligand. Additionally we are shipping G Protein-Coupled Receptor 132 Antibodies (55) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GPR132 29933 Q9UNW8
GPR132 56696 Q9Z282
Rat GPR132 GPR132 314480  
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Top G Protein-Coupled Receptor 132 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
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HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details

GPR132 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for G Protein-Coupled Receptor 132 (GPR132) Interaction Partners

Human G Protein-Coupled Receptor 132 (GPR132) interaction partners

  1. we found an additional novel G2A variant (G2A-b) that is the major transcript with functional response to ligand stimulation as well as G2A-a, and succeeded in discriminating proton-sensing and oxidized fatty acid-sensing activities of G2A.

  2. G2A is a negative modifier of lymphoid leukemogenesis initiated by the BCR-ABL oncogene

  3. In atherosclerotic plaques of human coronary arterial specimens, G2A is expressed by macrophages within the lipid-r (show APOE Proteins)ich plaques, whereas no immunoreactivity of G2A is observed in fibrous plaques where macrophages do not exist.

  4. G2A can activate a specific combination of G proteins, and G2A/LPC (show PCSK7 Proteins)-induced apoptosis involves both G alpha(13 (show GNA13 Proteins))- and G alpha(s (show GNAS Proteins))-mediated pathways

  5. G2A was not detected in either brain or skin vascular endothelial cell type.

  6. G2A is a proton-sensing G-protein-coupled receptor (show ADRA1A Proteins) antagonized by lysophosphatidylcholine

  7. Activity of the human G2A receptor is less sensitive to pH fluctuations as measured by inositol phosphate and cAMP accumulation.

  8. results indicate that G protein-coupled receptor G2A is a receptor for 9-hydroxyoctadecadienoic acid (9-HODE) and other oxidized free fatty acids and is activated by oxidized free fatty acids

  9. G2A latent within neutrophil secretory vesicles may facilitate signaling through lysophospholipids for neutrophil activation and calcium flux.

  10. 9-HODE-G2A signaling plays proinflammatory roles in skin under oxidative conditions

Mouse (Murine) G Protein-Coupled Receptor 132 (GPR132) interaction partners

  1. Lyso-PS signaled to macrophages in a G2A-dependent manner for their enhanced production of prostaglandin E2 (PGE2) via a calcium-dependent cytosolic phospholipase A2 (show PLA2G4A Proteins)/cyclooxygenase-mediated mechanism.

  2. G2A is expressed predominantly by macrophages within atherosclerotic lesions at the aortic root of apolipoprotein E (show APOE Proteins)-deficient mice.

  3. role of G2A in lysophosphatidylcholine-mediated T-cell migration

  4. G2A signaling regulates macrophage chemotaxis to lysophosp[hatidylcholine.

  5. data indicate the ability of lysophosphatidylcholine to stimulate macrophage & T-cell chemotaxis via G2A is not manifested in vivo & G2A-mediated proapoptotic rather than chemotactic action is most penetrant during atherogenesis

  6. the neuritogenic effect of sPLA2 is mediated by generation of LPC and subsequent activation of G2A

  7. Examination of lipoprotein profiles revealed elevated levels of circulating high-density lipoprotein (HDL (show HSD11B1 Proteins)) cholesterol in G2A-/- LDLR (show LDLR Proteins)-/- mice compared with their G2A+/+ LDLR (show LDLR Proteins)-/- counterparts after extended periods of diet intervention.

  8. Endothelial G2A expression may aid in prevention of vascular inflammation and atherosclerosis.

  9. The G2A receptor is important for hepatobiliary bile salt, cholesterol, and phospholipid homeostasis and for the pathogenesis of cholesterol gallstone formation.

  10. NADPH oxidase-dependent generation of lysophosphatidylserine enhances clearance of activated and dying neutrophils via G2A.

G Protein-Coupled Receptor 132 (GPR132) Protein Profile

Protein Summary

Receptor for an unknown ligand. Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May serve as a mechanism for T- and B-cells, and other cell types, to slow their proliferation and repair damaged DNA to ensure proper replication.

Gene names and symbols associated with GPR132

  • G protein-coupled receptor 132 (GPR132)
  • G protein-coupled receptor 132 (gpr132)
  • G protein-coupled receptor 132 (Gpr132)
  • G2a protein

Protein level used designations for GPR132

G protein-coupled receptor 132 , probable G-protein coupled receptor 132-like , G2 accumulation protein , probable G-protein coupled receptor 132 , G protein-coupled receptor G2A , G protein-coupled receptor G2a

GENE ID SPECIES
539146 Bos taurus
612704 Canis lupus familiaris
708463 Macaca mulatta
100145370 Xenopus (Silurana) tropicalis
100446639 Pongo abelii
100588329 Nomascus leucogenys
100615537 Pan troglodytes
29933 Homo sapiens
56696 Mus musculus
314480 Rattus norvegicus
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