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anti-G Protein-Coupled Receptor 81 (GPR81) Antibodies

G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.. Additionally we are shipping G Protein-Coupled Receptor 81 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPR81 243270  
GPR81 689936  
GPR81 27198 Q9BXC0
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Top anti-G Protein-Coupled Receptor 81 Antibodies at antibodies-online.com

Showing 10 out of 94 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GPR81 Antibody (C-term) in 293 cell line lysates (35ug/lane). This demonstrates the GPR81 antibody detected the GPR81 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Goat Un-conjugated EIA, WB Anti-FKSG80 (0.5g/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p) Pituitary, Anterior 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p) Anti-GPR81 antibody  ABIN1048875 IHC staining of human pituitary, anterior. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB GPR81 Antibody (C-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GPR81 antibody detected the GPR81 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Pancreas (formalin-fixed, paraffin-embedded) stained with GPR81 antibody ABIN213368 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of GPR81 expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of Pituitary using antibody ABIN122033 50 μg Log in to see 6 to 8 Days
$500.50
Details

GPR81 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-G Protein-Coupled Receptor 81 Antibodies

  1. Human Polyclonal GPR81 Primary Antibody for EIA, WB - ABIN952614 : Jeninga, Bugge, Nielsen, Kersten, Hamers, Dani, Wabitsch, Berger, Stunnenberg, Mandrup, Kalkhoven: Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81). in The Journal of biological chemistry 2009 (PubMed)
    Show all 3 references for ABIN952614

  2. Dog (Canine) Polyclonal GPR81 Primary Antibody for EIA, WB - ABIN615901 : Cai, Ren, Jin, Cheng, Kash, Chen, Wright, Taggart, Waters: Role of GPR81 in lactate-mediated reduction of adipose lipolysis. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against G Protein-Coupled Receptor 81 Interaction Partners

Mouse (Murine) G Protein-Coupled Receptor 81 (GPR81) interaction partners

  1. Results indicate that lactate may aggravated ischemic brain injury by activating GPR81 and inhibition of GPR81 protects against ischemia-induced cell death via an antiapoptosis pathway

  2. Description of a GPR81 selective agonist with in vivo efficacy, inhibiting lipolysis without flushing.

  3. Lactate negatively regulates TLR induction of the NLRP3 (show NLRP3 Antibodies) inflammasome and production of IL1beta (show IL1B Antibodies), via ARRB2 (show ARRB2 Antibodies) and GPR81 in liver and pancreatic injury.

  4. chronic obesity reduces GPR109A and GPR81 expression in the adipose tissue, while acute in vitro LPS treatment increases expression of GPR109A in adipocytes and macrophages.

  5. Inflammation decreases the expression of GPR81 in adipose tissue

  6. An autocrine lactate loop mediates insulin (show INS Antibodies)-dependent inhibition of lipolysis through GPR81.

  7. GPR81 couples to the Gi signaling pathway

  8. Data show that siRNA-mediated knockdown (show PPARG Antibodies)of PPARgamma in differentiated 3T3-L1 adipocytes showed a significant decrease in Gpr81 protein expression.

Human G Protein-Coupled Receptor 81 (GPR81) interaction partners

  1. HCA1/3 are necessary for breast cancer cells to balance lipid/fatty acid metabolism.

  2. HCAR1 and monocarboxylate transporters activity is required for the L- and D-lactate-mediated enhancement of DNA repair and of HeLa cell survival.

  3. Description of a GPR81 selective agonist with in vivo efficacy, inhibiting lipolysis without flushing.

  4. Data support that GPR81 is important for cancer cell regulation of lactate transport mechanisms.

  5. Lactate negatively regulates TLR induction of the NLRP3 (show NLRP3 Antibodies) inflammasome and production of IL1beta (show IL1B Antibodies), via ARRB2 (show ARRB2 Antibodies) and GPR81 in liver and pancreatic injury.

  6. demonstrated that the C165-E166-S167-F168 motif at the second extracellular loop is critical for GPR81 function, and the conserved six Cys (show DNAJC5 Antibodies) residues at the extracellular regions are necessary for GPR81 function

  7. GPR81 with relatively restricted expression in the adipose tissues functions as a receptor for lactate and can mediate an anti-lipolytic effect of lactate.

  8. Data show that the coordinated PPARgamma (show PPARG Antibodies)-mediated regulation of the GPR81, GPR109A and GPR109B presents a novel mechanism by which TZDs may reduce circulating free fatty acid levels and perhaps ameliorate insulin (show INS Antibodies) resistance in obese patients.

G Protein-Coupled Receptor 81 (GPR81) Antigen Profile

Protein Summary

G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.

Gene names and symbols associated with GPR81

  • G protein-coupled receptor 81 (GPR81) antibody
  • hydroxycarboxylic acid receptor 1 (HCAR1) antibody
  • hydroxycarboxylic acid receptor 1-1 (hcar1-1) antibody
  • G protein-coupled receptor 81 (LOC100345808) antibody
  • G protein-coupled receptor 81 (Gpr81) antibody
  • hydroxycarboxylic acid receptor 1 (GPR81) antibody
  • GPR81 antibody
  • gpr81-1 antibody
  • GPR104 antibody
  • HCA1 antibody
  • Hcar1 antibody
  • LACR1 antibody
  • TA-GPCR antibody

Protein level used designations for GPR81

G protein-coupled receptor 81 , G-protein coupled receptor 81 , hydroxycarboxylic acid receptor 1 , G protein-coupled receptor 104 , G-protein coupled receptor 104 , T-cell activation G protein-coupled receptor , hydroxy-carboxylic acid receptor 1 , lactate receptor 1

GENE ID SPECIES
452331 Pan troglodytes
538759 Bos taurus
570755 Danio rerio
702825 Macaca mulatta
100345808 Oryctolagus cuniculus
243270 Mus musculus
689936 Rattus norvegicus
486252 Canis lupus familiaris
27198 Homo sapiens
100153287 Sus scrofa
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