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GPR87 encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. Additionally we are shipping GPR87 Proteins (3) and many more products for this protein.
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Human Polyclonal GPR87 Primary Antibody for EIA, WB - ABIN952617
Tabata, Baba, Shiraishi, Ito, Fujita: The orphan GPCR GPR87 was deorphanized and shown to be a lysophosphatidic acid receptor. in Biochemical and biophysical research communications 2007
Show all 2 references for ABIN952617
Human Polyclonal GPR87 Primary Antibody for IF, ELISA - ABIN1535752
Okazoe, Zhang, Liu, Shibuya, Ueda, Sugimoto, Kakehi: Expression and Role of GPR87 in Urothelial Carcinoma of the Bladder. in International journal of molecular sciences 2013
Show all 2 references for ABIN1535752
knockdown of GPR87 led to a p53 (show TP53 Antibodies)-dependent signal transduction and caused apoptosis in the bladder cancer cells.
This study aimed to clarify the role of GPR87 in urothelial carcinoma of the bladder.
GPR87 promotes the growth and metastasis of CD133(+) cancer stem-like cells, and our findings may reveal new targets for HCC (show FAM126A Antibodies) prevention or therapy
Results suggest that the GPR87 is a LPA (show APOA Antibodies) receptor which evolved from a common ancestor of P2Y (show P2RY1 Antibodies) receptors.
G-protein coupled receptor (show ADRA1A Antibodies)(GPR87) stands out as a candidate for further target validation due to its marked overexpression and correlation on a mutation-based level to squamous cell carcinoma
Human GPR87 mRNA transcript was preferentially overexpressed in squamous cell carcinomas. Up-regulation of both, transcript and protein, was detected in samples of SCC (show CYP11A1 Antibodies) of the lung, cervix, skin and head and neck (pharynx, larynx and epiglottis).
GPR87 knockdown sensitized cancer cells to DNA damage-induced growth suppression via enhanced p53 (show TP53 Antibodies) stabilization and activation.
Results suggest that the GPR87 is a LPA receptor which evolved from a common ancestor of P2Y (show P2RY1 Antibodies) receptors.
This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589).
G protein-coupled receptor 87
, G-protein coupled receptor 87
, G-protein coupled receptor 87-like
, G protein-coupled receptor 95
, G-protein coupled receptor 95
, orphan GPCR 87