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anti-GRB2-Related Adaptor Protein (GRAP) Antibodies

GRAP encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. Additionally we are shipping GRAP Proteins (5) and GRAP Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GRAP 10750 Q13588
GRAP 71520 Q9CX99
GRAP 363616  
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Top anti-GRAP Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN184595 (0.3µg/ml) staining of human thymus lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GRAP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: THP-1 cell lysate WB Suggested Anti-GRAP  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from 293/MCF-7/COLO cells, using GRAP Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of methanol-fixed A549, using GRAP, antibody at 1:500 dilution. IHC-P Image Immunohistochemical analysis of paraffin-embedded U373 xenograft, using GRAP, antibody at 1:100 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB Host: RabbitTarget Name: GrapAntibody Dilution: 1.0ug/mlSample Tissue: Rat Spleen 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details

GRAP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GRAP Antibodies

  1. Cow (Bovine) Polyclonal GRAP Primary Antibody for WB - ABIN374088 : Feng, Ouyang, Hu, Shi, Gentz, Ni: Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway. in The Journal of biological chemistry 1996 (PubMed)
    Show all 2 references for ABIN374088

More Antibodies against GRAP Interaction Partners

Human GRB2-Related Adaptor Protein (GRAP) interaction partners

  1. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from fibrotic kidneys from diabetic patients, and subsequently confirmed a (show TGFB1 Antibodies)s a novel component of TGF-beta signaling in cultured human renal tubule cells.

  2. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome.

  3. Our findings define a pathway involving CD28 (show CD28 Antibodies) binding to Grb-2 (show GRB2 Antibodies) and its co-operativity with Vav1 (show VAV1 Antibodies) in the regulation of T-cell co-stimulation.

Mouse (Murine) GRB2-Related Adaptor Protein (GRAP) interaction partners

  1. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from diabetic mice, indicating a potential novel role for GRAP in TGF-beta (show TGFB1 Antibodies)-induced tubule injury in diabetic kidney disease.

  2. Data suggest that Grap, unlike Grb2 (show GRB2 Antibodies), acts as a negative regulator of TCR-stimulated intracellular signaling by downregulating signal relay through the Ras/Erk (show EPHB2 Antibodies) pathway.

  3. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome.

  4. FcgammaRIIB docking site for the SH2 (show MYO15 Antibodies) domain-containing adapters Grb2 (show GRB2 Antibodies) and Grap

GRAP Antigen Profile

Protein Summary

This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

Gene names and symbols associated with GRAP

  • GRB2-related adaptor protein (GRAP) antibody
  • GRB2-related adaptor protein a (grapa) antibody
  • zgc:109892 (zgc:109892) antibody
  • GRB2-related adaptor protein (Grap) antibody
  • 8430435N19Rik antibody
  • BB233594 antibody
  • grap antibody
  • MGC109892 antibody
  • si:dkeyp-9d4.1 antibody
  • zgc:110202 antibody

Protein level used designations for GRAP

GRB2-related adaptor protein , GRB2-related adapter protein , growth factor receptor-bound protein 2-related adaptor protein

GENE ID SPECIES
416523 Gallus gallus
489534 Canis lupus familiaris
553596 Danio rerio
555184 Danio rerio
10750 Homo sapiens
71520 Mus musculus
363616 Rattus norvegicus
534491 Bos taurus
Selected quality suppliers for anti-GRAP (GRAP) Antibodies
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