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The protein encoded by GULP1 is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Additionally we are shipping GULP, Engulfment Adaptor PTB Domain Containing 1 Proteins (8) and GULP, Engulfment Adaptor PTB Domain Containing 1 Kits (4) and many more products for this protein.
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Dog (Canine) Polyclonal GULP1 Primary Antibody for IHC (p), WB - ABIN374220
Su, Nakada-Tsukui, Tosello-Trampont, Li, Bu, Henson, Ravichandran: Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP). in The Journal of biological chemistry 2002
GULP1 only mediates LRP1 (show LRP1 Antibodies) transactivation
The apoptotic engulfment protein Ced-6 participates in clathrin-mediated yolk uptake in Drosophila egg chambers.
GULP expression positively regulates TGF-beta (show TGFB1 Antibodies) signaling leading to growth inhibition, this may represent an attractive target to achieve TGF-beta (show TGFB1 Antibodies) responsiveness in ovarian cells.
This study identify GULP1 as a novel neuronal amyloid-beta precursor protein interacting protein that alters trafficking and processing of amyloid-beta precursor protein.
overexpression of GULP1 enhanced the generation of APP (show APP Antibodies) CTFs (C-terminal fragments) and Abeta (show APP Antibodies), whereas knockdown of GULP1 suppressed APP (show APP Antibodies) CTFs and Abeta (show APP Antibodies) production.
these results indicate that GULP functions as an adaptor protein for stabilin-1 (show STAB1 Antibodies)-mediated phagocytosis.
the GULP1 gene and the apoptotic engulfment pathway are involved in schizophrenia in subjects of European ancestry
Interaction of CED-6/GULP, an adapter protein (show TOLLIP Antibodies) involved in engulfment of apoptotic cells with CED-1 (show IFT122 Antibodies) and CD91 (show LRP1 Antibodies)/low density lipoprotein receptor (show LDLR Antibodies)-related protein (LRP (show LRP1 Antibodies)).
GULP is a likely downstream molecule in the stabilin-2 (show STAB2 Antibodies)-mediated signaling pathway and plays an important role in stabilin-2 (show STAB2 Antibodies)-mediated phagocytosis
Phosphatidylserine-recognizing SR-BI activates associated GULP; activated GULP induces MAPK phosphorylation; activated MAPK increases GTP-bound Rac1; and activated Rac1 induces a rearrangement of the actin cytoskeleton.
Jedi-1 (show PEAR1 Antibodies) signals through recruitment of GULP, which promotes phagocytosis through a noncanonical phosphoclathrin-dependent mechanism.
in this study we report the identification of a novel C. elegans CED-6-like orthologue in mouse, which has probable apoptotic like function
The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene.
GULP, engulfment adaptor PTB domain containing 1
, PTB domain adaptor protein CED-6
, ptb domain-containing engulfment adapter protein 1
, CED-6 protein
, ced-6 protein
, PTB domain adapter protein CED-6
, PTB domain-containing engulfment adapter protein 1
, cell death protein 6 homolog
, engulfment adapter protein
, CED 6