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GJC1 is a member of the connexin gene family. Additionally we are shipping GJC1 Proteins (5) and many more products for this protein.
Showing 10 out of 84 products:
Cow (Bovine) Polyclonal GJC1 Primary Antibody for WB - ABIN2774871
Terrier-Lacombe, Guillou, Maire, Terrier, Vince, de Saint Aubain Somerhausen, Collin, Pedeutour, Coindre: Dermatofibrosarcoma protuberans, giant cell fibroblastoma, and hybrid lesions in children: clinicopathologic comparative analysis of 28 cases with molecular data--a study from the French Federation of Cancer Centers Sarcoma Group. in The American journal of surgical pathology 2002
Show all 2 references for ABIN2774871
Human Polyclonal GJC1 Primary Antibody for ELISA, WB - ABIN1451265
Zody, Garber, Adams, Sharpe, Harrow, Lupski, Nicholson, Searle, Wilming, Young, Abouelleil, Allen, Bi, Bloom, Borowsky, Bugalter, Butler, Chang, Chen, Cook, Corum, Cuomo, de Jong, DeCaprio, Dewar et al.: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. ... in Nature 2006
Chicken Polyclonal GJC1 Primary Antibody for WB - ABIN2774861
Rackauskas, Kreuzberg, Pranevicius, Willecke, Verselis, Bukauskas: Gating properties of heterotypic gap junction channels formed of connexins 40, 43, and 45. in Biophysical journal 2007
The ablation of Cx45 reduced neuronal loss by approximately 50% under ischemic insult.
This study demonstrated using Cx45-eGFP transgenic mice that Cx45-eGFP cells are distributed along the rostrocaudal extent of the spinal cord with expression mainly restricted to the grey matter of dorsal laminae I-III
Prostaglandin E stimulates Connexin isoforms via GSK-3beta (show GSK3b Antibodies)/beta-catenin (show CTNNB1 Antibodies) via EP2-receptor-dependent cAMP/PKA and PI3K/Akt (show AKT1 Antibodies) in mouse embryonic stem cells.
Suggest critical role for Cx45 in the regulation of endothelial-induced mesenchymal cell differentiation towards a mural cell phenotype.
Cx45 is required for optimal impulse propagation in the atrioventricular node; cardiomyocyte-directed deficiencies of Cx45 in mice lead to embryonic lethality attributable to morphological and functional cardiovascular defects.
Cx45 is physiologically expressed in vascular smooth muscle
Residual Cx45 and its relationship to Cx43 (show GJA1 Antibodies) in murine ventricular myocardium.
The cx45 strongly modulate the firing pattern of individual RGCs, ensuring strongly correlated firing between nearby RGCs and normal patterning of retinogeniculate projections.
Data suggest that Cx45 is expressed on OFF bipolar cell dendrites, presumably forming gap junctions with cells of the same type, and on OFF bipolar cell axon terminals, presumably forming heterologous gap junctions with other retinal neurons.
Data suggest that Cx45 and Cx36 (show GJD2 Antibodies) have similar functions in the retina, whereas Cx45 fulfills special functions in the developing heart that cannot be compensated by Cx36 (show GJD2 Antibodies).
Connexin45 has much more rapid gating kinetics than connexin43 (show GJA1 Antibodies)
Results found that the expression of Cx26 (show GJB2 Antibodies) and Cx45 had no prognostic value but Cx43 (show GJA1 Antibodies) was upregulated in tumour epithelia and membrane Cx43 (show GJA1 Antibodies) expression was associated with short overall survival time.
Gap junctional intercellular communication in human bladder smooth muscle cells and suburothelial myofibroblastsdepend of Cx43 (show GJA1 Antibodies) rather than on Cx45.
Our data suggest that GJA7 alterations have no or low genetic relevance in nonsyndromic hearing loss in populatins from Turkey, South Africa, United Kingdom, United States, and China.
DNA hypermethylation of the promoter region of GJC1, encoding connexin45, is an important mechanism in silencing gene expression in colorectal cancer.
Study shows that fusion of a V5/6-His tag (hexa (show HEXA Antibodies) moiety M r = 0.93 kDa) to the CT segment of Cx40 (show GJA5 Antibodies), Cx43 (show GJA1 Antibodies) and Cx45 does not prevent the cells from forming channels.
connexin genes Gjd2 (show GJD2 Antibodies) coding for mCx36, Gjc1 coding for mCx45 and Gja10 (show GJA9 Antibodies) coding for mCx57 in the mouse, a subset of 4 connexin genes, including the unique GJA9 (Cx59 (show GJA9 Antibodies)) and GJA10 (Cx62 (show GJa10 Antibodies)), could be detected at least as transcript isoforms in the human retina.
Results show that Cx40 (show GJA5 Antibodies), Cx37 (show GJA4 Antibodies), Cx43 (show GJA1 Antibodies) and Cx45 were expressed within the glomeruli.
Studies indicate that 21 different Cxs have been detected and they are generally named according to their approximate molecular mass in Kda, e.g. Cx32 (show GJB1 Antibodies), Cx43 (show GJA1 Antibodies) and Cx45.
abnormal expression of connexin43 (show GJA1 Antibodies) and connexin45 in nasopharynx tissues may be associated with cancerization and squamatization of human nasopharynx tissue
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described.
gap junction protein, gamma 1, 45kDa
, connexin 45
, gap junction protein, alpha 7, 45kDa
, gap junction protein, delta 3, 31.9kDa
, gap junction membrane channel protein alpha 7
, gap junction gamma-1 protein-like
, Gap junction alpha-7 protein
, gap junction gamma-1 protein
, gap junction delta-3 protein
, gap junction membrane channel protein chi 1
, gap junction alpha-7 protein
, gap junction channel protein connexin 45
, gap junction protein, alpha 7, 45kDa (connexin 45)