Glycoprotein Galactosyltransferase alpha 1, 3 Proteins (GGTA1)

Transfer of galactose from UDP-galactose to an acceptor molecule (R).

list all proteins Gene Name GeneID UniProt
Rat GGTA1 GGTA1 652927  
GGTA1 14594 P23336
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Top GGTA1 Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details

GGTA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,

More Proteins for Glycoprotein Galactosyltransferase alpha 1, 3 (GGTA1) Interaction Partners

Cow (Bovine) Glycoprotein Galactosyltransferase alpha 1, 3 (GGTA1) interaction partners

  1. The results suggest that in alpha1,3-GalT (show GALT Proteins) the substrate-assisted catalysis would be necessary in both mechanisms, because the nucleophilic strength of Glu317 is reduced by the interactions it makes to ensure proper acceptor binding.

Pig (Porcine) Glycoprotein Galactosyltransferase alpha 1, 3 (GGTA1) interaction partners

  1. Many waitlisted renal transplant patients have minimal xenoreactive antibody binding to the GGTA1/CMAH/B4GalNT2 (show B4GALNT2 Proteins) knockout pig, but some HLA antibodies in sensitized patients cross-react with class I SLA (show SLA Proteins).

  2. Silencing the porcine CMAH/GGTA1 genes necessary to avoid antibody-mediated rejection in a pig-to-human model also reduces the xenogeneic consumption of human platelets by the porcine liver.

  3. alpha 1-3-N-acetylgalactosaminyltransferase (show B4GALNT2 Proteins)-knockout pig did not appear to have an advantage over the GalT (show GALT Proteins)-KO pig with respect to reactivity with human antibodies from a xenotransplantation perspective

  4. GGTA1/CMAH knockout pig samples had increased relative amounts of high-mannose, incomplete, and xylosylated N-linked glycans

  5. study demonstrated that ZFN is an efficient tool in creating gene-modified pigs. GGTA1 null pigs and GGTA1 null fetal fibroblasts would benefit research and pig-to-human transplantation

  6. Anti-gal (show GAL Proteins) antibodies in alpha1,3-galactosyltransferase gene-knockout pigs.

  7. Human CD55 (show CD55 Proteins) expression blocks hyperacute rejection and restricts complement activation in Gal (show GAL Proteins) knockout cardiac xenografts.

  8. These multidisciplinary results suggest that genetic modification to eliminate the alphaGal epitopes in the extracellular matrix (ECM (show MMRN1 Proteins)) bioscaffolds had not altered the properties of these ECM (show MMRN1 Proteins) bioscaffolds.

  9. transgenic male pigs were produced that possess an alpha alpha-1,3-galactosyltransferase knockout allele and express a randomly inserted human alpha 1,2-fucosylosyltransferase transgene

  10. Higher antibody binding and cytotoxicity to wild type cells compared with alpha1,3-galactosyltransferase gene-knockout cells show greater cytotoxicity to antibodies.

GGTA1 Protein Profile

Protein Summary

Transfer of galactose from UDP-galactose to an acceptor molecule (R).

Gene names and symbols associated with GGTA1

  • ABO-family member 5 (Ggta1)
  • alpha-1,3-galactosyltransferase (GGTA1)
  • alpha-galactosyltransferase 1 (glycoprotein) (GGTA1)
  • glycoprotein galactosyltransferase alpha 1, 3 (Ggta1)
  • glycoprotein, alpha-galactosyltransferase 1 (GGTA1)
  • N-acetyllactosaminide alpha-1,3-galactosyltransferase-like (GGTA1)
  • alpha1,3GT protein
  • alpha3GalT protein
  • AW108479 protein
  • Gal protein
  • GALT protein
  • Ggta protein
  • Ggta-1 protein
  • Glt6d1 protein

Protein level used designations for GGTA1

ABO-family member protein 5 , N-acetyllactosaminide alpha-1,3-galactosyltransferase , UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase , galactosyltransferase , glycosyltransferase 6 domain-containing protein 1 , alpha1,3-galactosyltransferase , alpha Gal , glycoprotein alpha galactosyl transferase 1 , alpha-1,3-galactosyltransferase , Galactosyltransferase

GENE ID SPECIES
652927 Rattus norvegicus
493877 Felis catus
281780 Bos taurus
14594 Mus musculus
396733 Sus scrofa
100390928 Callithrix jacchus
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