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anti-Glypican 3 (GPC3) Antibodies

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Additionally we are shipping Glypican 3 Kits (57) and Glypican 3 Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPC3 2719 P51654
GPC3 14734 Q8CFZ4
GPC3 25236 P13265
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Top anti-Glypican 3 Antibodies at antibodies-online.com

Showing 10 out of 171 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB GPC3 Antibody (C-term) western blot analysis in NCI-H292 cell line lys... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IF, WB Immunofluorecence staining of anti-GPC3 Pab (ABIN390319) on HepG2 cell... GPC3 Antibody C349 (ABIN390319) western blot analysis in HepG2 cell li... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Immunofluorecence staining of anti-GPC3 Pab (ABIN390317) on HepG2 cell... GPC3 Antibody C35 (ABIN390317) western blot analysis in HepG2 cell lin... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, WB Immunofluorecence staining of anti-GPC3 Pab (ABIN652202) on HepG2 cell... GPC3 Antibody P544 (ABIN652202) western blot analysis in mouse lung ti... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF Immunofluorecence staining of GPC3 Antibody on HepG2 cells. The cells ... Western blot analysis in HepG2 cell line lysates using GPC3 Antibody  ... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$423.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green... Figure 2: Flow cytometric analysis of Jurkat cells using GPC3 mouse mA... 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB 1 mL Log in to see 6 to 8 Days
$797.50
Details
Human Rabbit Un-conjugated IHC (p) Flow cytometric analysis of rabbit anti-Glypican-3 (SP86) antibody in ... 7 mL Log in to see 2 to 3 Days
$367.00
Details

GPC3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-Glypican 3 Antibodies

  1. Human Polyclonal Glypican 3 Primary Antibody for EIA, WB - ABIN952555 : Lai, Oseini, Moser, Yu, Elsawa, Hu, Nakamura, Han, Aderca, Isomoto, Garrity-Park, Shire, Li, Sanderson, Adjei, Fernandez-Zapico, Roberts: The oncogenic effect of sulfatase 2 in human hepatocellular carcinoma is mediated in part by glypican 3-dependent Wnt activation. in Hepatology (Baltimore, Md.) 2010 (PubMed)
    Show all 5 references for ABIN952555

  2. Human Polyclonal Glypican 3 Primary Antibody for EIA, IF - ABIN1449428 : Nakatsura, Kageshita, Ito, Wakamatsu, Monji, Ikuta, Senju, Ono, Nishimura: Identification of glypican-3 as a novel tumor marker for melanoma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2004 (PubMed)
    Show all 5 references for ABIN1449428

  3. Human Polyclonal Glypican 3 Primary Antibody for IF, WB - ABIN390319 : Boily, Saikali, Sinnett: Methylation analysis of the glypican 3 gene in embryonal tumours. in British journal of cancer 2004 (PubMed)
    Show all 3 references for ABIN390319

  4. Human Polyclonal Glypican 3 Primary Antibody for IF, WB - ABIN652202 : Wichert, Stege, Midorikawa, Holm, Lage: Glypican-3 is involved in cellular protection against mitoxantrone in gastric carcinoma cells. in Oncogene 2004 (PubMed)
    Show all 3 references for ABIN652202

  5. Human Monoclonal Glypican 3 Primary Antibody for ICC, FACS - ABIN969523 : Zittermann, Capurro, Shi, Filmus: Soluble glypican 3 inhibits the growth of hepatocellular carcinoma in vitro and in vivo. in International journal of cancer. Journal international du cancer 2010 (PubMed)
    Show all 2 references for ABIN969523

  6. Human Monoclonal Glypican 3 Primary Antibody for EIA, IF - ABIN1107403 : Takai, Ashihara, Ishiguro, Terashima, Watanabe, Kato, Suzuki: Involvement of glypican-3 in the recruitment of M2-polarized tumor-associated macrophages in hepatocellular carcinoma. in Cancer biology & therapy 2010 (PubMed)
    Show all 2 references for ABIN1107403

  7. Cow (Bovine) Polyclonal Glypican 3 Primary Antibody for WB - ABIN2780199 : Bhave, Mars, Donthamsetty, Zhang, Tan, Luo, Bowen, Michalopoulos: Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex. in The American journal of pathology 2013 (PubMed)
    Show all 2 references for ABIN2780199

More Antibodies against Glypican 3 Interaction Partners

Human Glypican 3 (GPC3) interaction partners

  1. GPC3 expression was measured in hepatocellular carcinoma at different stages and correlated with prognosis. CK19 (show KRT19 Antibodies)+/GPC3+ HCC (show FAM126A Antibodies) has the highest risk of intrahepatic metastasis, microvascular invasion, regional lymph node involvement, and distant metastasis.

  2. Review: Glypican-3 is a highly specific biomarker for the diagnosis of hepatocellular carcinoma and a promising therapeutic target.

  3. In South Korean hepatocellular carcinoma patients, GPC3 expression was more frequent in hepatocellular carcinoma with aggressive features, but it was not an independent prognostic biomarker.

  4. In this meta-analysis, GPC3 was found to be acceptable as a serum marker for the diagnosis of hepatocellular carcinoma.

  5. GPC3 may be a candidate marker for detecting lung squamous cell carcinoma.

  6. study suggests that GPC3 is involved in HCC (show FAM126A Antibodies) cell migration and motility through HS chain-mediated cooperation with the HGF (show HGF Antibodies)/Met pathway, showing how HS targeting has potential therapeutic implications for liver cancer

  7. potential role of GPC3 in urothelial carcinogenesis warrants further investigation, especially the potential use of Glypican-3 for therapeutic and diagnostic purposes

  8. Downregulation of glypican-3 expression increases migration, invasion, and tumorigenicity of ovarian cancer.

  9. GPC3 expression is an independent prognostic factor for postoperative hepatocellular carcinoma

  10. Identify a GPC3-specific T-cell receptor. Expression of this receptor by T cells allows them to recognize and kill GPC3-positive hepatoma cells.

Mouse (Murine) Glypican 3 (GPC3) interaction partners

  1. Coupling of pGPC3 to liposomes was essential for effective priming of GPC3-specific CTLs.

  2. The expression of GPC-3 was altered by DEN treatment.

  3. Data suggest that GPC3 down-regulates hepatocyte proliferation by binding to hedgehog (show SHH Antibodies) (HH) and down-regulating the HH signaling pathway and binding with CD81 (show CD81 Antibodies), thus making it unavailable to bind to Hhex (show HHEX Antibodies) and causing its nuclear translocation.

  4. Finding represents a rare four layer genomic overlap consisting of growth associated quantitative trait locus (QTL), body mass associated Gpc3 gene, highly conserved miRNA gene and mature miRNA seed SNP identified in the lean mouse.

  5. Hepatocyte overexpression of GPC3 suppresses hepatocyte proliferation and liver regeneration and alters gene expression profiles.

  6. glypican-3 is involved in the recruitment of M2-polarized tumor-associated macrophages in hepatocellular carcinoma

  7. GPC3 inhibits the PI3K/Akt (show AKT1 Antibodies) anti-apoptotic pathway while it stimulates the p38MAPK (show MAPK14 Antibodies) stress-activated one in murine mammary adenocarcinoma LM3 cells

  8. Gpc3 function in development of Simpson-Golabi-Behmel syndrome is IGF-independent

  9. GPC3 knockout mice exhibit alterations in the Wnt (show WNT2 Antibodies) signaling pathway, which is also associated with the regulation of cell proliferation

  10. Polymorphisms in the 3' untranslated region of Gpc3 are strong candidates for the causal sequence variation and loss-of-function mutations can cause overgrowth and developmental abnormalities.

Glypican 3 (GPC3) Antigen Profile

Protein Summary

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Glypican 3 (GPC3) Antibodies

  • glypican 3 (gpc3) antibody
  • glypican 3 (GPC3) antibody
  • glypican 3 (Gpc3) antibody
  • DGSX antibody
  • Glypican-3 antibody
  • GPC3 antibody
  • GTR2-2 antibody
  • MXR7 antibody
  • OCI-5 antibody
  • SDYS antibody
  • SGB antibody
  • SGBS antibody
  • SGBS1 antibody

Protein level used designations for anti-Glypican 3 (GPC3) Antibodies

glypican 3 , glypican-3-like , glypican proteoglycan 3 , glypican-3 , heparan sulphate proteoglycan , intestinal protein OCI-5 , secreted glypican-3 , defective in Simpson-Golabi-Behmel overgrowth syndrome , proteoglycan GPC3 , Intestinal protein OCI-5

GENE ID SPECIES
387365 Danio rerio
706773 Macaca mulatta
100023253 Monodelphis domestica
100135027 Xenopus (Silurana) tropicalis
100401118 Callithrix jacchus
100444952 Pongo abelii
100477314 Ailuropoda melanoleuca
100548246 Meleagris gallopavo
100591673 Nomascus leucogenys
2719 Homo sapiens
481056 Canis lupus familiaris
615239 Bos taurus
14734 Mus musculus
25236 Rattus norvegicus
100351858 Oryctolagus cuniculus
100726246 Cavia porcellus
100516171 Sus scrofa
770863 Gallus gallus
101119285 Ovis aries
465866 Pan troglodytes
Selected quality suppliers for anti-Glypican 3 (GPC3) Antibodies
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