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Glypican 3 antibody (Middle Region)

GPC3 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit IHC, WB Host: Rabbit Polyclonal unconjugated
Pubmed (1 reference)
Catalog No. ABIN2780199
$418.92
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  • Target See all Glypican 3 (GPC3) Antibodies
    Glypican 3 (GPC3)
    Binding Specificity
    • 28
    • 16
    • 13
    • 10
    • 9
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 182
    • 60
    • 50
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
    Host
    • 113
    • 69
    • 2
    Rabbit
    Clonality
    • 94
    • 90
    Polyclonal
    Conjugate
    • 63
    • 14
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glypican 3 antibody is un-conjugated
    Application
    • 107
    • 101
    • 62
    • 58
    • 50
    • 38
    • 17
    • 17
    • 6
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Sequence
    FSTIHDSIQY VQKNAGKLTT TIGKLCAHSQ QRQYRSAYYP EDLFIDKKVL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against GPC3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human GPC3
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 580 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bhave, Mars, Donthamsetty, Zhang, Tan, Luo, Bowen, Michalopoulos: "Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex." in: The American journal of pathology, Vol. 183, Issue 1, pp. 153-9, (2013) (PubMed).

  • Target
    Glypican 3 (GPC3)
    Alternative Name
    GPC3 (GPC3 Products)
    Synonyms
    GPC3 antibody, sgb antibody, dgsx antibody, sdys antibody, sgbs antibody, oci-5 antibody, sgbs1 antibody, DGSX antibody, GTR2-2 antibody, MXR7 antibody, OCI-5 antibody, SDYS antibody, SGB antibody, SGBS antibody, SGBS1 antibody, Glypican-3 antibody, glypican 3 antibody, gpc3 antibody, GPC3 antibody, Gpc3 antibody
    Background
    Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome.
    Alias Symbols: SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2
    Protein Interaction Partner: UBC, WNT3A, WNT7B, IGF2, FGF2,
    Protein Size: 580
    Molecular Weight
    64 kDa
    Gene ID
    2719
    NCBI Accession
    NM_004484, NP_004475
    UniProt
    P51654
    Pathways
    Glycosaminoglycan Metabolic Process
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