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Glypican 3 antibody (AA 21-50)

GPC3 Reactivity: Human, Mouse IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031098
$578.58
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  • Target See all Glypican 3 (GPC3) Antibodies
    Glypican 3 (GPC3)
    Binding Specificity
    • 28
    • 16
    • 13
    • 10
    • 9
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-50
    Reactivity
    • 182
    • 61
    • 50
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 113
    • 69
    • 2
    Rabbit
    Clonality
    • 94
    • 90
    Polyclonal
    Conjugate
    • 63
    • 14
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glypican 3 antibody is un-conjugated
    Application
    • 107
    • 101
    • 61
    • 58
    • 50
    • 38
    • 17
    • 17
    • 6
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Purification
    Purified
    Immunogen
    A portion of amino acids 21-50 from the human protein was used as the immunogen for this Glypican 3 antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the Glypican 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the Glypican 3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Glypican 3 (GPC3)
    Alternative Name
    Glypican 3 (GPC3 Products)
    Synonyms
    GPC3 antibody, sgb antibody, dgsx antibody, sdys antibody, sgbs antibody, oci-5 antibody, sgbs1 antibody, DGSX antibody, GTR2-2 antibody, MXR7 antibody, OCI-5 antibody, SDYS antibody, SGB antibody, SGBS antibody, SGBS1 antibody, Glypican-3 antibody, glypican 3 antibody, gpc3 antibody, GPC3 antibody, Gpc3 antibody
    Background
    GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
    UniProt
    P51654
    Pathways
    Glycosaminoglycan Metabolic Process
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