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anti-Grainyhead-Like 2 (Drosophila) (GRHL2) Antibodies

The protein encoded by GRHL2 is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Additionally we are shipping GRHL2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GRHL2 79977 Q6ISB3
GRHL2 252973 Q8K5C0
GRHL2 299979  
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Top anti-GRHL2 Antibodies at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Grhl2 AntibodyTitration: 1.0 µg/mL  Positive Control: Rat Stomach 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Brain, cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of GRHL2 expression in transfected 293T cell line by GRHL2 MaxPab polyclonal antibody.Lane 1: GRHL2 transfected lysate(68.75 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to GRHL2 on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB GRHL2 Antibody (Center) (ABIN657072) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the GRHL2 antibody detected the GRHL2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Rat Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details

GRHL2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
,

, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-GRHL2 Antibodies

  1. Human Polyclonal GRHL2 Primary Antibody for ELISA, WB - ABIN566411 : Kang, Chen, Kim, Kang, Park: Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells. in Oncogene 2009 (PubMed)
    Show all 4 references for ABIN566411

  2. Human Polyclonal GRHL2 Primary Antibody for IF, WB - ABIN529152 : Dompe, Rivers, Li, Cordes, Schwickart, Punnoose, Amler, Seshagiri, Tang, Modrusan, Davis: A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis. in Proceedings of the National Academy of Sciences of the United States of America 2011 (PubMed)
    Show all 2 references for ABIN529152

  3. Chicken Polyclonal GRHL2 Primary Antibody for IHC, WB - ABIN2778358 : Van Laer, Van Eyken, Fransen, Huyghe, Topsakal, Hendrickx, Hannula, Mäki-Torkko, Jensen, Demeester, Baur, Bonaconsa, Mazzoli, Espeso, Verbruggen, Huyghe, Huygen, Kunst, Manninen, Konings, Diaz-Lacava, Steffens, Wienker, Pyykkö, Cremers, Kremer, Dhooge, St: The grainyhead like 2 gene (GRHL2), alias TFCP2L3, is associated with age-related hearing impairment. in Human molecular genetics 2008 (PubMed)

More Antibodies against GRHL2 Interaction Partners

Human Grainyhead-Like 2 (Drosophila) (GRHL2) interaction partners

  1. Taken together, our results demonstrate a role for miR (show MLXIP Antibodies)-217 in the regulation of keratinocyte differentiation, partially through the regulation of GRHL2.

  2. Genetic variations in the EYA4 (show EYA4 Antibodies), GRHL2 and DFNA5 (show DFNA5 Antibodies) genes and their interactions with occupational noise exposure may play an important role in the incidence of noise-induced hearing loss (NIHL).

  3. GRHL1 (show GRHL1 Antibodies), GRHL2, and GRHL3 (show GRHL3 Antibodies) have roles in cellular proliferation, differentiation, adhesion, and polarity and may promote cancer or be tumor suppressors [review]

  4. The p63 (show RPE65 Antibodies) gene is regulated by GRHL2 through reciprocal feedback and determines the epithelial phenotype in human keratinocytes.

  5. A Grhl2-dependent gene network controls trophoblast branching morphogenesis.

  6. has identified ZEB1 (show ZEB1 Antibodies) as a target of GRHL2 and suggested a reciprocal GRHL2-ZEB1 (show ZEB1 Antibodies) repressive relationship, providing a novel mechanism through which proliferation may be modulated in colorectal cancer cells.

  7. Mutations in GRHL2 result in an autosomal-recessive ectodermal Dysplasia syndrome.

  8. Over-expression of Grhl2 decreased c-Myc (show MYC Antibodies) and Bcl-2 (show BCL2 Antibodies) protein expression level.

  9. These findings indicate that GRHL2 may be a noise-induced hearing loss susceptibility gene and that polymorphisms of GRLH2 may contribute to the etiology of noise-induced hearing loss.

  10. expression of GRHL2 is directly suppressed by the ZEB1 (show ZEB1 Antibodies), which in turn is a direct target for repression by GRHL2, suggesting that the EMT (show ITK Antibodies) transcription factors GRHL2 and ZEB1 (show ZEB1 Antibodies) form a double negative regulatory feedback loop

Mouse (Murine) Grainyhead-Like 2 (Drosophila) (GRHL2) interaction partners

  1. GRHL2 promotes the epithelial nature of non-neural ectoderm during dynamic events of neural tube formation by both activating key epithelial genes and actively suppressing epithelial-mesenchymal (EMT (show ITK Antibodies)) transition through novel downstream EMT (show ITK Antibodies) suppressors.

  2. a Grhl2/Ovol2 (show OVOL2 Antibodies) network controls Cldn4 (show CLDN4 Antibodies) and Rab25 (show RAB25 Antibodies) expression that facilitates lumen expansion and barrier formation in subtypes of renal epithelia

  3. Our findings reveal important pathophysiological differences between human pulmonary fibrosis and specific mouse models of fibrosis and support a crucial role of GRHL2 in epithelial activation in lung fibrosis and perhaps also in epithelial plasticity.

  4. expression of GRHL2 is directly suppressed by the ZEB1 (show ZEB1 Antibodies), which in turn is a direct target for repression by GRHL2, suggesting that the EMT (show ITK Antibodies) transcription factors GRHL2 and ZEB1 (show ZEB1 Antibodies) form a double negative regulatory feedback loop

  5. Grhl2 plays an essential role in the determination of epithelial phenotype of breast cancers, EMT (show ITK Antibodies) and tumor progression

  6. the results indicate that Grhl2 regulates epithelial morphogenesis through transcriptional up-regulation of Cldn3 (show CLDN3 Antibodies) and Cldn4 (show CLDN4 Antibodies), as well as of Rab25 (show RAB25 Antibodies), which increases the Cldn4 (show CLDN4 Antibodies) protein and its localization at TJs

  7. Grhl2 and Nkx2-1 (show NKX2-1 Antibodies) bind to each other's promoter in vivo, forming a positive feedback regulatory loop.

  8. Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse

  9. tissue closure defects in Grhl2 mutants are similar to that of AP-2alpha (show TFAP2A Antibodies) null mutants and AP-2alpha (show TFAP2A Antibodies) has been shown to bind to the promoter of E-cadherin (show CDH1 Antibodies)

  10. Both GRHL2 and GRHL3 (show GRHL3 Antibodies) bind to and regulate expression of the wound repair gene Rho GEF (show ARHGEF2 Antibodies) 19, but regulation of the barrier forming gene, Transglutaminase 1 (TGase1 (show TGM1 Antibodies)), is unique to GRHL3 (show GRHL3 Antibodies).

Zebrafish Grainyhead-Like 2 (Drosophila) (GRHL2) interaction partners

  1. The data showed that midbrain-hindbrain boundary maintenance and morphogenesis are dissociable events regulated by grhl2b through diverse transcriptional targets.

  2. This work reveals an evolutionarily conserved function of Grhl2 in otic development and provides a fish model for further studying mechanisms of Grhl2-related hearing loss.

GRHL2 Antigen Profile

Protein Summary

The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28).

Gene names and symbols associated with GRHL2

  • grainyhead-like 2 (Drosophila) (GRHL2) antibody
  • grainyhead-like 2 (Drosophila) (Grhl2) antibody
  • grainyhead-like 2b (Drosophila) (grhl2b) antibody
  • 0610015A08Rik antibody
  • BOM antibody
  • DFNA28 antibody
  • grhl2 antibody
  • RGD1561191 antibody
  • si:dkey-21k18.2 antibody
  • Tcfcp2l3 antibody
  • TFCP2L3 antibody

Protein level used designations for GRHL2

grainyhead-like 2 (Drosophila) , transcription factor CP2-like 3 , brother of mammalian grainyhead , grainyhead-like protein 2 homolog , grainyhead like 2 , grainyhead-like 2 , grainyhead-like 2b protein

GENE ID SPECIES
464320 Pan troglodytes
706549 Macaca mulatta
100056140 Equus caballus
429506 Gallus gallus
79977 Homo sapiens
481985 Canis lupus familiaris
519918 Bos taurus
252973 Mus musculus
299979 Rattus norvegicus
100034503 Danio rerio
Selected quality suppliers for anti-GRHL2 (GRHL2) Antibodies
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