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Grancalcin, EF-Hand Calcium Binding Protein Proteins (GCA)

GCA product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. Additionally we are shipping Grancalcin Antibodies (20) and Grancalcin Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GCA 227960 Q8VC88
Rat GCA GCA 295647  
GCA 25801 P28676
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Top Grancalcin Proteins at antibodies-online.com

Showing 9 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human GST tag   50 μg Log in to see 5 Days
$385.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$467.86
Details
HOST_Human Cells Human His tag 20 μg Log in to see 16 Days
$393.75
Details
Human Un-conjugated   2 μg Log in to see 6 Days
$168.54
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GCA Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
,

Top referenced Grancalcin Proteins

  1. Human Grancalcin Protein expressed in Escherichia coli (E. coli) - ABIN667865 : Boyhan, Casimir, French, Teahan, Segal: Molecular cloning and characterization of grancalcin, a novel EF-hand calcium-binding protein abundant in neutrophils and monocytes. in The Journal of biological chemistry 1992 (PubMed)
    Show all 2 references for ABIN667865

More Proteins for Grancalcin, EF-Hand Calcium Binding Protein (GCA) Interaction Partners

Mouse (Murine) Grancalcin, EF-Hand Calcium Binding Protein (GCA) interaction partners

  1. Homozygous Gca (show GUCA1A Proteins) mutants appeared healthy and reproduced normally. Leukocyte recruitment into the peritoneal cavity upon induction of inflammation was not significantly affected by the absence of grancalcin.

  2. findings suggest that grancalcin plays a key role in leukocyte-specific functions that are responsible for host defense

  3. Adhesion to fibronectin (show FN1 Proteins) of grancalcin-deficient neutrophils was decreased by 60% compared to control cells.

Human Grancalcin, EF-Hand Calcium Binding Protein (GCA) interaction partners

  1. Results indicate that heterodimerization of GCA (show NPR1 Proteins) and TLR9 (show TLR9 Proteins) is important for TLR9 (show TLR9 Proteins)-mediated downstream signaling and might serve to fine tune processes against viral infection.

  2. GCA (show NPR1 Proteins) interacts with SRI (show SRI Proteins) in vivo and in vitro.

  3. The reported type 1 diabetes association is from a linkage disequilibrium region including three candidate genes, FAP, IFIH1 (show IFIH1 Proteins) and GCA (show NPR1 Proteins).

  4. IFIH1 (show IFIH1 Proteins) interferon (show IFNA Proteins) induced helicase, GCA grancalcin or the potassium channel (show KCNAB2 Proteins) KCNH7 (show KCNH7 Proteins) - are potential candidates implicated in the pathogenesis of multiple sclerosis.

  5. IFIH1 (show IFIH1 Proteins)-GCA (show NPR1 Proteins)-KCNH7 (show KCNH7 Proteins) locus is not associated with genetic susceptibility to multiple sclerosis in French patients

Grancalcin (GCA) Protein Profile

Protein Summary

This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction\; with magnesium alone, it partitions with the granule fraction\; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.

Gene names and symbols associated with GCA

  • zgc:92027 (zgc:92027)
  • grancalcin, EF-hand calcium binding protein (GCA)
  • Grancalcin (gran)
  • grancalcin (LOC100280890)
  • grancalcin (Gca)
  • 5133401E04Rik protein
  • AI573844 protein
  • GCL protein
  • Grancalcin protein

Protein level used designations for GCA

grancalcin , Grancalcin , grancalcin, EF-hand calcium-binding protein , grancalcin, penta-EF-hand protein

GENE ID SPECIES
449543 Danio rerio
100174456 Pongo abelii
100195546 Salmo salar
100280890 Zea mays
227960 Mus musculus
295647 Rattus norvegicus
25801 Homo sapiens
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