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anti-Granulysin (GNLY) Antibodies

The product of GNLY is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. Additionally we are shipping Granulysin Kits (13) and Granulysin Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GNLY 10578 P22749
GNLY    
GNLY    
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Top anti-Granulysin Antibodies at antibodies-online.com

Showing 10 out of 71 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in MDA-MB435 cell line lysates (35 ug/lane) using GNLY Antibody (C-term) Cat.-No. AP51884PU-N. This demonstrates the GNLY antibody detected the GNLY protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB GNLY Antibody (N-term) (ABIN656999) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the GNLY antibody detected the GNLY protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS 2 mL Log in to see 6 to 8 Days
$286.00
Details
Human Mouse Biotin Func, FACS 500 μg Log in to see 10 to 12 Days
$538.09
Details
Human Mouse PE FACS, IP 100 Tests Log in to see 10 to 12 Days
$250.03
Details
Human Mouse Alexa Fluor 647 FACS 100 Tests Log in to see 10 to 12 Days
$271.76
Details
Human Mouse FITC FACS   1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human larynx labeled with Rabbit Anti-GNLY/NKG5 Polyclonal Antibody, Unconjugated (ABIN742320) at 1:200 followed by conjugation to the secondary antibody and DAB staining paraformaldehyde-fixed, paraffin embedded human laryngocarcinoma tissue; Antigen retrieval with 0.01M citrate buffer(pH6) boiling for 15 minutes; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with Rabbit Anti-GNLY/NKG5 Polyclonal Antibody, Unconjugated  at 1:200 overnight at 4°C, followed by a conjugated secondary and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details

GNLY Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Granulysin Antibodies

  1. Human Monoclonal GNLY Primary Antibody for FACS - ABIN2657203 : Kaspar, Okada, Kumar, Poulain, Drouvalakis, Kelekar, Hanson, Kluck, Hitoshi, Johnson, Froelich, Thompson, Newmeyer, Anel, Clayberger, Krensky: A distinct pathway of cell-mediated apoptosis initiated by granulysin. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 7 references for ABIN2657203

  2. Human Monoclonal GNLY Primary Antibody for FACS, IP - ABIN2663711 : Krensky, Clayberger: Biology and clinical relevance of granulysin. in Tissue antigens 2009 (PubMed)
    Show all 6 references for ABIN2663711

  3. Human Monoclonal GNLY Primary Antibody for Func, FACS - ABIN2660773 : Kalb, Glaser, Stary, Koszik, Stingl: TRAIL(+) human plasmacytoid dendritic cells kill tumor cells in vitro: mechanisms of imiquimod- and IFN-?-mediated antitumor reactivity. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Show all 4 references for ABIN2660773

  4. Human Polyclonal GNLY Primary Antibody for EIA, WB - ABIN952622 : Xing, Wu, Wang, Krensky, Mody, Zheng: Granulysin production and anticryptococcal activity is dependent upon a far upstream enhancer that binds STAT5 in human peripheral blood CD4+ T cells. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 2 references for ABIN952622

More Antibodies against Granulysin Interaction Partners

Human Granulysin (GNLY) interaction partners

  1. serum GNLY is closely associated with the clinical characteristics of nasopharyngeal carcinoma and may be a potential biomarker for nasopharyngeal carcinoma

  2. GNLY delivers Gzms into three protozoan parasites (Trypanosoma cruzi, Toxoplasma gondii and Leishmania major), in which the Gzms generate superoxide and inactivate oxidative defense enzymes to kill the parasite.

  3. Studies indicate that cytotoxic mechanisms mediated by granulysin and TRAIL (TNF-related apoptosis inducing ligand (show TNFSF10 Antibodies)) seem to be less secondary effects on normal tissues.

  4. High Granulysin expression is associated with Cutaneous T Cell Lymphoma and Sezary Syndrome.

  5. A three-way interaction between SNPs in HLA-DQ and GNLY was identified in terms of HBV clearance.

  6. GNLY-expressing lymphocytes, probably attracted by IL-15 (show IL15 Antibodies), not only participate partially in myocardial cell apoptosis, but also hasten resolution of cardiac leukocyte infiltration in patients with myocardial infarction.

  7. Serum granulysin levels were significantly elevated in both acute and chronic alopecia areata patients.

  8. Human, but not rodent, cytotoxic granules also contain granulysin, an antimicrobial peptide (show cAMP Antibodies) in addition to granzymes; study shows that granulysin delivers granzymes into bacteria to kill diverse bacterial strains.

  9. It was concluded taht granulysin induces apoptosis on hematological tumor cells and on cells from B-cell lymphocytic leukemia patients, opening the door to research on its use as a new anti-tumoral treatment.

  10. suggested that the alteration of circulating granulysin has potential function in host immune response against TB and HIV/TB coinfection

Cow (Bovine) Granulysin (GNLY) interaction partners

  1. Intercaruncular epithelium granulysin may play important roles in the establishment and maintenance of gestation during normal pregnancy.

Granulysin (GNLY) Antigen Profile

Protein Summary

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with anti-Granulysin (GNLY) Antibodies

  • granulysin (GNLY) antibody
  • 519 antibody
  • D2S69E antibody
  • LAG-2 antibody
  • LAG2 antibody
  • NKG5 antibody
  • TLA519 antibody

Protein level used designations for anti-Granulysin (GNLY) Antibodies

granulysin , T-cell activation protein 519 , T-lymphocyte activation gene 519 , lymphocyte-activation gene 2 , lymphokine LAG-2

GENE ID SPECIES
459370 Pan troglodytes
100125622 Ovis aries
10578 Homo sapiens
404173 Bos taurus
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