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anti-Gremlin 2 (GREM2) Antibodies

GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Additionally we are shipping Gremlin 2 Proteins (6) and Gremlin 2 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GREM2 289264  
GREM2 23893 O88273
GREM2 64388 Q9H772
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Top anti-Gremlin 2 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GREM2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate WB Suggested Anti-GREM2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control:.21_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of Gremlin 2 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IP Immunoprecipitation of GREM2 transfected lysate using anti-GREM2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with GREM2 purified MaxPab mouse polyclonal antibody (B01P) . 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged GREM2 is 3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB GREM2 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$375.83
Details
Human Mouse Un-conjugated WB Western Blot analysis of GREM2 expression in transfected 293T cell line by GREM2 MaxPab polyclonal antibody.Lane 1: GREM2 transfected lysate(18.48 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 9 Days
$430.00
Details

GREM2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against Gremlin 2 Interaction Partners

Zebrafish Gremlin 2 (GREM2) interaction partners

  1. Through regulation of bone morphogenetic protein signaling, GREM2 is required for cardiac laterality and atrial differentiation during embryonic development.

  2. Gremlin 2 regulates distinct roles of BMP and Endothelin 1 (show EDN1 Antibodies) signaling in dorsoventral patterning of the facial skeleton.

  3. Prdc is expressed in the developing eyes and the first two pharyngeal arches, in the outer layers of the optic cup, in the arch mesenchyme expands stepwise to the remaining posterior arches, and in the somites and the the swim bladder.

Mouse (Murine) Gremlin 2 (GREM2) interaction partners

  1. Grem2 expression is regulated during development and embryonic stem cell differentiation.

  2. PRDC binds heparin with high affinity and that heparin binding to PRDC interferes with BMP antagonism.

  3. We show that Tbx2 directly represses Grem1 in distal regions of the posterior limb mesenchyme allowing Bone morphogenetic protein (Bmp) signaling to abrogate Fgf4/9/17 expression in the overlying epithelium.

  4. Through a combination of biophysical and biochemical studies, the authors determined that PRDC forms biologically active dimers that potently inhibit BMP ligands.

  5. The differential regulation of Gremlin2 gene expressions by BMP2 (show BMP2 Antibodies) may explain the critical function of these genes during osteoblast differentiation.

  6. ovarian PRDC expressed in granulosa cells could be involved in follicular development by antagonizing the actions of theca cell-derived Bone morphogenetic proteins

  7. We propose that PRDC might serve as a mediator to antagonize BMP-4 (show BMP4 Antibodies) signaling by Wnt (show WNT2 Antibodies).

  8. PRDC expression in osteoblasts suppresses differentiation and that reduction of PRDC expression promotes osteogenesis in vitro. PRDC is accordingly identified as a potential novel therapeutic target for the regulation of bone formation.

Human Gremlin 2 (GREM2) interaction partners

  1. Gremlin 2 inhibits adipocyte differentiation through activation of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling

  2. GREM2 variants have been identified in atrial fibrillation cohort studies, demonstrating abnormalities in cardiac excitation - supra ventricular tachycardia and atrial fibrillation.

  3. The minor allele of rs4454537 is significantly associated with low bone density at the total hip of southern Chinese people. Our study further suggests GREM2 as a novel susceptibility gene for osteoporosis.

  4. Through regulation of bone morphogenetic protein signaling, GREM2 is required for cardiac laterality and atrial differentiation during embryonic development.

  5. and that a genetic variant in the FMN2 (show FMN2 Antibodies)/GREM2 locus influences GREM2 expression in osteoblasts and thereby trabecular number and thickness as well as fracture risk.

Gremlin 2 (GREM2) Antigen Profile

Protein Summary

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.

Gene names and symbols associated with anti-Gremlin 2 (GREM2) Antibodies

  • gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) (GREM2) antibody
  • gremlin 2 (GREM2) antibody
  • gremlin 2, cysteine knot superfamily (grem2) antibody
  • gremlin 2 (Grem2) antibody
  • gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis) (Grem2) antibody
  • gremlin 2, DAN family BMP antagonist (GREM2) antibody
  • CKTSF1B2 antibody
  • DAND3 antibody
  • Gremlin2 antibody
  • PRDC antibody
  • RGD1560008 antibody
  • zgc:112207 antibody

Protein level used designations for anti-Gremlin 2 (GREM2) Antibodies

gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) , gremlin 2, cysteine knot superfamily, homolog , gremlin-2 , protein related to DAN and cerberus homolog , gremlin 2, cysteine knot superfamily , gremlin 2 homolog, cysteine knot superfamily , Gremlin1 , cysteine knot superfamily 1, BMP antagonist 2 , protein related to DAN and cerberus , DAN domain family member 3

GENE ID SPECIES
421507 Gallus gallus
469727 Pan troglodytes
490367 Canis lupus familiaris
550399 Danio rerio
100194915 Salmo salar
100528649 Ictalurus punctatus
289264 Rattus norvegicus
23893 Mus musculus
64388 Homo sapiens
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